PLVAP antibody

Principal name

PLVAP antibody

Alternative names for PLVAP antibody

Plasmalemma vesicle protein 1, PV1, PV-1, MECA-32 antigen, FELS, Endothelial cell marker, Endothelial cell surface marker, Endothelial Cell Antigen, Plasmalemma vesicle-associated protein, Fenestrated endothelial-linked structure protein

SwissProt ID

Q91VC4 (Mouse), Q9BX97 (Human), Q9WV78 (Rat)

Gene ID

83483 (PLVAP), 84094 (Plvap), 834839 (ERF1-1)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P)

Background of PLVAP antibody

PLVAP is a 60kD protein which is otherwise known as MECA-32 and PV-1. PLVAP is a transmembrane homodimer which is associated with endothelial cell caveolae and fenestrae. In adult and embryonic mice, PLVAP is primarily expressed on endothelial tissues but shows restricted distribution in the skeletal, cardiac and brain tissues. In embryonic mice, PLVAP expression, on the vasculature associated with blood brain barrier has been reported to be developmentally regulated. In humans, PLVAP is selectively up-regulated in a variety of high-grade brain tumors, including glioblastoma and metastatic carcinoma, as well as other cerebral disorders associated with blood-brain barrier disruption, such as acute ischemia. PLVAP represents a novel marker of brain tumour angiogenesis and integrity of the blood-brain barrier and is a potential therapeutic target.

General readings

Keuschnigg, J., et al. Blood 114(2):478-484(2009)
Carson-Walter, E.B., et al. Clin. Cancer Res. 11(21):7643-7650(2005)
Strickland, L.A., et al. J. Pathol. 206(4):466-475(2005)
Stan, R.V., et al. Mol. Biol. Cell 15(8):3615-3630(2004)
Hnasko, R., et al. J. Endocrinol. 175(3):649-661(2002)
Stan, R.V., et al. Genomics 72(3):304-313(2001)
Stan, R.V., et al. J. Cell Biol. 145(6):1189-1198(1999)

16 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PLVAP antibody

PLVAP Rat IgG2a MECA-32 Biotin Ms C, F
0.1 mg / €250.00
  Acris Antibodies GmbH

PLVAP antibody

PLVAP Rat IgG2a MECA-32 FITC Ms F
0.1 mg / €280.00
  Acris Antibodies GmbH

PLVAP antibody

PLVAP Rat IgG2a MECA-32 Purified Ms C, F
0.25 mg / €400.00
  Acris Antibodies GmbH

PLVAP antibody

PLVAP Rat IgG2a MECA-32 Purified Ms C, F
0.1 mg / €240.00
  Acris Antibodies GmbH

PLVAP antibody

PLVAP Rat IgG2a MECA-32 Purified Ms C, F
25 µg / €170.00
  Acris Antibodies GmbH

PLVAP antibody

PLVAP Mouse IgG1 174/2 FITC Hu C, ICC/IF, WB
0.1 mg / €560.00
  Acris Antibodies GmbH

PLVAP antibody

PLVAP Mouse IgG1 174/2 Purified Hu C, ICC/IF, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

PLVAP (Center) antibody

Western blot analysis of PLVAP Antibody (Center) Cat.-No AP53357PU-N in HL-60 cell line lysates (35ug/lane). PLVAP (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PLVAP antibody

PLVAP Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

PLVAP antibody

pan Endothelial Cell Ag Antibody (MECA-32) [NB100-77668] - bEND.3 cells stained with MECA-32 Alexa Fluor® 488. Rat IgG2a MECA-32 Aff - Purified Ms C, F, ICC/IF, IP, P, WB
0.5 mg / €400.00
  Novus Biologicals Inc.

PLVAP antibody

pan Endothelial Cell Ag Antibody (MECA-32) [Biotin] [NB100-77669] - bEND.3 cells stained with MECA-32 biotin, followed by Sav-PE. Rat IgG2a MECA-32 Biotin Ms F
0.5 mg / €780.00
  Novus Biologicals Inc.

PLVAP antibody

Immunohistochemistry-Paraffin: PLVAP Antibody [NBP1-83911] - Immunohistochemical staining of human vulva/anal skin shows distinct positivity in endothelial cells. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PLVAP

PLVAP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PLVAP

PLVAP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PLVAP

PLVAP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PLVAP overexpression lysate

PLVAP overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

16 Item(s)

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