PLXDC1 / TEM7 antibody

Principal name

PLXDC1 / TEM7 antibody

Alternative names for PLXDC1 / TEM7 antibody

TEM3, Plexin domain-containing protein 1, Tumor endothelial marker 7, Tumor endothelial marker 3

SwissProt ID

Q8IUK5 (Human), Q91ZV7 (Mouse)

Gene ID

57125 (PLXDC1), 72324 (Plxdc1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Frozen Sections (C), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PLXDC1 / TEM7 antibody

Recently, using SAGE (Serial Alysis of Gene Expression) technology, St. Croix et al, have identified 46 genes, whose expression is specifically elevated in tumor-associated endothelium. Nine of these genes were prominently expressed only in tumor endothelial cells (EC), but were absent or barely detectable in normal ECs, and med as Tumor Endothelial Markers (TEMs, TEM 1-9). TEM7 (Tumor endothelial marker 7) transcripts are specifically expressed in the endothelium of colorectal cancer, primary cancers of lung, pancreas, breast, and brain. TEM7 is expressed specifically in endothelium of these cancers, whether primary or metastasis. The other six members of this family (TEM1, 3, 4, 5, 8, and 9) also show similar expression pattern in lung and brain tumors, and liver metastasis. Since most of the genes expressed differentially in tumor endothelium are also expressed during angiogenesis, these newly discovered genes might provide important resources for basic and clinical studies of human angiogenesis.

General readings

Fuchs,B., (2007) Gene 399 (2), 137-143

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PLXDC1 / TEM7 antibody

  Mouse Monoclonal TEM7/PLXDC1 Antibody (197C193 (IM193))  
Western Blot: TEM7 Antibody (197C193 (IM193)) [TA336403] - detection of TEM7 with TEM7 antibody. Human HCT-116 cell lysate probed with TEM7 antibody at 1 ug/ml. Mouse IgG1 197C193 (IM193) Purified Hu, Ms, Rt C, ICC/IF, IP, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PLXDC1 / TEM7 (C-term) antibody

  Rabbit Polyclonal TEM7 Antibody  
Western blot analysis of TEM7 in human liver tissue lysate with TEM7 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PLXDC1 / TEM7 (Center) antibody

  Rabbit Polyclonal TEM7 Antibody  
Western blot analysis of TEM7 in rat liver tissue lysate with TEM7 antibody at (A) 0.5 and (B) 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PLXDC1 / TEM7 antibody

  Rabbit polyclonal anti-PLXDC1 antibody  
Immunohistochemical analysis of paraffin-embedded human brain tissue using PLXDC1 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

PLXDC1 / TEM7 antibody

  Rabbit Polyclonal Anti-PLXDC1 Antibody  
WB Suggested Anti-PLXDC1 Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

PLXDC1 / TEM7 antibody

Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt C, E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PLXDC1 / TEM7 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using PLXDC1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P
50 µg / €230.00
  Assay Biotech

PLXDC1 / TEM7 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using PLXDC1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

PLXDC1 - human gene knockout kit via CRISPR

PLXDC1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PLXDC1 - human gene knockout kit via CRISPR

PLXDC1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PLXDC1 - human gene knockout kit via CRISPR

PLXDC1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PLXDC1 - human gene knockout kit via CRISPR

PLXDC1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Plxdc1 - mouse gene knockout kit via CRISPR

Plxdc1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Plxdc1 - mouse gene knockout kit via CRISPR

Plxdc1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Plxdc1 - mouse gene knockout kit via CRISPR

Plxdc1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Plxdc1 - mouse gene knockout kit via CRISPR

Plxdc1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PLXDC1 / TEM7

  Recombinant protein of human plexin domain containing 1 (PLXDC1)  
PLXDC1 / TEM7 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

PLXDC1 overexpression lysate

PLXDC1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PLXDC1 (mGFP-tagged) - Human plexin domain containing 1 (PLXDC1), 200 uL, >10^7 TU/mL

Lenti ORF particles, PLXDC1 (mGFP-tagged) - Human plexin domain containing 1 (PLXDC1), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, PLXDC1 (Myc-DDK tagged) - Human plexin domain containing 1 (PLXDC1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, PLXDC1 (Myc-DDK tagged) - Human plexin domain containing 1 (PLXDC1) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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