PMVK antibody

Principal name

PMVK antibody

Alternative names for PMVK antibody

Phosphomevalonate kinase, PMKase, PMKI, HUMPMKI

SwissProt ID

Q15126 (Human), Q29081 (Pig), Q2KIU2 (Bovin), Q9D1G2 (Mouse), Q9VIT2 (Drome)

Gene ID

10654 (PMVK)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F)

Background of PMVK antibody

PMVK (phosphomevalonate kinase) is a cytosolic enzyme that catalyzes the conversion of mevalonate-5-phosphate to mevalonate-5-diphosphate. It is mapped to chromosome 1p13-1q22-23 and spans more than 8.4 kb in the human genome. PMVK is a peroxisomal protein which requires the C-terminal peroxisomal targeting signal, Ser-Arg-Leu, for localization to the organelle. It was expressed highly in heart, liver, skeletal muscle, kidney and pancreas and slightly lower in brain, placenta, and lung. And PMKase gene expression is subject to regulation by sterol at the level of transcription. It is a single copy gene covering less than 15 kb in the human genome. The human PMKase amino acid sequence contains a consensus peroxisomal targeting sequence (PTS-1), Ser-Arg-Leu, at the C terminus of the protein.

General readings

Cho Y K., et al. (2001) J Biol chem. 278:4510-4515.
Hogenboom S., et al. (2004) J Lipid Res. 45:697-705.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PMVK antibody

Anti-PMVK mouse monoclonal antibody (TA503447) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PMVK(RC202867). Mouse IgG2a OTI1C12 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PMVK antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PMVK (RC202867, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PMVK. Mouse IgG2b OTI2D1 Purified Hu, Ms WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

PMVK antibody

Anti-PMVK mouse monoclonal antibody (TA503449) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PMVK(RC202867). Mouse IgG2a OTI2F9 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PMVK antibody

The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PMVK antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Lane 1. : HeLa cell lysate 
Lane 2. : HepG2 cell lysate 
Lane 3. : Jukat cell lysate 
Lane 4. : MCF7 cell lysate 
Lane 5. : A549 cell lysate Mouse AT21C10 Purified Hu E, F, ICC/IF, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

PMVK antibody

The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PMVK antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Lane 1. : HeLa cell lysate 
Lane 2. : HepG2 cell lysate 
Lane 3. : Jukat cell lysate 
Lane 4. : MCF7 cell lysate 
Lane 5. : A549 cell lysate Mouse AT21C10 Purified Hu E, F, ICC/IF, WB
50 µl / €220.00
  Acris Antibodies GmbH

PMVK antibody

Immunohistochemical analysis of paraffin embedded rat skeletal muscle sections, staining PMVK in cytoplasm, DAB chromeric reaction Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

PMVK antibody

PMVK MaxPab polyclonal antibody. Western Blot analysis of PMVK expression in human kidney. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

PMVK antibody

PMVK MaxPab polyclonal antibody. Western Blot analysis of PMVK expression in human kidney. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

PMVK antibody

PMVK Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

PMVK antibody

PMVK Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PMVK antibody

PMVK Mouse IgG2a 2B8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PMVK antibody

PMVK Mouse IgG2a 2B8 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

PMVK antibody

Immunohistochemical analysis of paraffin-embedded rat skeletal muscle sections, stain PMVK in cytoplasm DAB chromogenic reaction. Rabbit Hu, Ms, Rt P
0.1 mg / €390.00
  Abnova Taiwan Corp.

PMVK antibody

PMVK Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

PMVK antibody

PMVK Rabbit IgG Hu WB
0.1 ml / €340.00
  Novus Biologicals Inc.

PMVK antibody

Immunohistochemistry-Paraffin: PMVK Antibody [NBP1-83142] - Immunohistochemical staining of human placenta shows strong positivity in decidual cells and trophoblastic cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PMVK

PMVK Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

PMVK

PMVK Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €399.00
  OriGene Technologies, Inc.

PMVK (1-192, His-tag)

PMVK Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

PMVK (1-192, His-tag)

PMVK Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

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