POLA1 antibody

Principal name

POLA1 antibody

Alternative names for POLA1 antibody

DNA polymerase alpha catalytic subunit, DNA polymerase alpha catalytic subunit p180

SwissProt ID

O89042 (Rat), P09884 (Human), P33609 (Mouse), Q9DE46 (Xenla)

Gene ID

5422 (POLA1), 18968 (Pola1)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Frozen Sections (C), Immunoprecipitation (IP)

Background of POLA1 antibody

DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases. DNA pol α, β, δ and ε are involved in DNA replication and repair. DNA pol δ and DNA pol ε are multisubunit enzymes, with DNA pol δ consisting of two subunits: p125, which interacts with the sliding DNA clamp protein PCNA; and p50. The nuclear-encoded DNA pol γ is the only DNA polymerase required for the replication of the mitochondrial DNA. DNA pol ζ is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis. DNA pol θ is a DNA polymerase-helicase that binds ATP and is involved in the repair of interstrand crosslinks.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

POLA1 antibody

Immunocytochemical detection of DNA polymerase alpha on aceton fixed HEp-II with AM26670PU-S Mouse IgG1 CL22-2-42B Purified Hu C, F, ICC/IF
50 µg / €360.00
  Acris Antibodies GmbH

POLA1 antibody

Western blot analysis of extracts from Jurkat cells, 293 cells and HepG2 cells, using DNA Polymerase a antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

POLA1 antibody

Western blot analysis of DNA Polymerase a expression in 293 cells Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

POLA1 antibody

Western blot (WB) analysis of DNA pol α antibody (Cat.-No.: AP06662PU-N) in extracts from A549 cells. Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

POLA1 antibody

POLA1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

POLA1 antibody

POLA monoclonal antibody (M01), clone 3C11 Western Blot analysis of POLA expression in HeLa NE ( Cat # L013V3 ). Mouse IgG2a 3C11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

POLA1 antibody

Western blot analysis of extracts from HepG2/293/Jurkat cells, using DNA Polymerase alpha Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

POLA1 antibody

Western blot analysis of extracts from HepG2/293/Jurkat cells, using DNA Polymerase alpha Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

POLA1 antibody

Western blot analysis of DNA Polymerase alpha 1 expression in A549 (A); A431 (B); HeLa (C) whole cell lysates. Rabbit Aff - Purified Hu IP, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

POLA1 antibody

Western blot analysis of DNA Polymerase alpha 1 expression in A549 (A); A431 (B); HeLa (C) whole cell lysates. Rabbit Aff - Purified Hu IP, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

POLA1 antibody

Western blot analysis of DNA Polymerase alpha 1 expression in A549 (A); A431 (B); HeLa (C) whole cell lysates. Rabbit Aff - Purified Hu IP, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CRISPR

Catalog No. Species Donor Vector  

POLA1 - human gene knockout kit via CRISPR

POLA1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

POLA1 - human gene knockout kit via CRISPR

POLA1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

POLA1 - human gene knockout kit via CRISPR

POLA1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

POLA1 - human gene knockout kit via CRISPR

POLA1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

POLA1

POLA1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

POLA1

POLA1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, POLA1 (mGFP-tagged)-Human polymerase (DNA directed), alpha 1, catalytic subunit (POLA1), 200 uL, >10^7 TU/mL

Lenti ORF particles, POLA1 (mGFP-tagged)-Human polymerase (DNA directed), alpha 1, catalytic subunit (POLA1), 200 uL, >10^7 TU/mL  
200 µl / €2,530.00
  OriGene Technologies, Inc.

Lenti ORF particles, POLA1 (Myc-DDK-tagged)-Human polymerase (DNA directed), alpha 1, catalytic subunit (POLA1), 200 uL, >10^7 TU/mL

Lenti ORF particles, POLA1 (Myc-DDK-tagged)-Human polymerase (DNA directed), alpha 1, catalytic subunit (POLA1), 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Pola1 (GFP-tagged) - Mouse polymerase (DNA directed), alpha 1 (Pola1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Pola1 (GFP-tagged) - Mouse polymerase (DNA directed), alpha 1 (Pola1), 200 uL, >10^7 TU/mL  
200 µl / €2,390.00
  OriGene Technologies, Inc.

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