POLD2 antibody

Principal name

POLD2 antibody

Alternative names for POLD2 antibody

DNA polymerase delta subunit 2, DNA polymerase delta subunit p50

SwissProt ID

O35654 (Mouse), O93610 (Xenla), P49004 (Bovin), P49005 (Human), Q6AXY4 (Rat)

Gene ID

5425 (POLD2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine)

Available hosts

Rabbit, Mouse, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of POLD2 antibody

DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases (1). In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches (2). These exonucleases include the family of DNA polymerases (3). DNA pol α, β, ∂, and e are involved in DNA replication and repair (4). DNA pol ∂ and DNA pol e are multisubunit enzymes, with DNA pol ∂ consisting of two subunits p125, which interacts with the sliding DNA clamp protein PCNA, and p50 (5). The nuclear-encoded DNA pol © is the only DNA polymerase required for the replication of the mitochondrial DNA (6). DNA pol Ω is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis (7). DNA pol œ is a DNA polymerase-helicase that binds ATP and is involved in the repair of interstrand crosslinks (8).

General readings

1. Liu L., et al. J. Biol. Chem., 278, 10041-10047 (2003).
2. Bermudez V.P., et al. J. Biol. Chem., 277, 36853-36862 (2003).
3. Goldsby R.E., et al. Proc. Natl. Acad. Sci. USA., 99,
15560-15565 (2002).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

POLD2 antibody

POLD2 Antibody (Center) (Cat. #TA325187) western blot analysis in Hela,HepG2 cell line and rat liver tissue lysates (35ug/lane).This demonstrates the POLD2 antibody detected the POLD2 protein (arrow). Rabbit IgG Purified Bov, Hu, Ms, Rt WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

POLD2 antibody

Western blot analysis of DNA polymerase delta p50 small subunit expression in Jurkat cells (Lane 1), Raji cells (Lane 2), HeLa cells (Lane 3), WR19L cells (Lane 4), and PC12 cells (Lane 5) using AM20280AF-N DNA polymerase delta antibody Rat IgG2a 7B4 Azide Free Hu, Ms, Rt WB
0.1 mg / €360.00
  Acris Antibodies GmbH

POLD2 antibody

Immunofluorescence of purified MaxPab antibody to POLD2 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

POLD2 antibody

Western Blot analysis of POLD2 expression in transfected 293T cell line (H00005425-T02) by POLD2 MaxPab polyclonal antibody.

Lane 1: POLD2 transfected lysate(51.30 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

POLD2 antibody

Human Heart; WB Suggested Anti-POLD2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human heart; POLD2 antibody - N-terminal region (ARP48694_P050) in Human Heart cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

POLD2 antibody

Western Blot: DNA polymerase delta p50 Antibody [NBP1-58097] - This Anti-POLD2 antibody was used in Western Blot of Fetal Heart tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

POLD2 antibody

Immunohistochemistry-Paraffin: DNA polymerase delta p50 Antibody [NBP1-90925] - Immunohistochemical staining of human colon shows strong nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

POLD2 (transcript variant 2)

POLD2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

POLD2 (transcript variant 1)

POLD2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

POLD2

POLD2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

POLD2

POLD2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

POLD2 (Human) Matched Antibody Pair

POLD2 (Human) Matched Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

POLD2 293T Cell Transient Overexpression Lysate(Denatured)

POLD2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

POLD2 overexpression lysate

POLD2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

14 Item(s)

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