POLE1 antibody

Principal name

POLE1 antibody

Alternative names for POLE1 antibody

DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A, POLE

SwissProt ID

Q07864  (Human), Q9WVF7 (Mouse)

Gene ID

5426 (POLE)

Available reactivities

Hu (Human), Mky (Monkey), Ms (Mouse), Md (Mustelid), Bov (Bovine), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of POLE1 antibody

DNA polymerase epsilon from HeLa cells differs from yeast pol epsilon in that HeLa pol epsilon contains two subunits of 220 and 55 kDa, whereas yeast pol epsilon has one large subunit and three smaller subunits. Previous studies of template specificity of HeLa pol epsilon, which appears to be required for long patch DNA repair in permeabilized cells, indicate pol epsilon prefers long stretches of single-stranded regions in poly(dA)-oligo(dT) as template. HeLa pol alpha and pol delta prefer activated DNA and alternating poly(dA-dT) as templates, respectively. Pol epsilon retains its processivity in the absence of proliferating cell nuclear antigen (PCNA), unlike pol delta. PCNA can also interact with Pol epsilon on linear DNA templates, even in the absence of other auxiliary factors (replication factor C, replication factor A), and thereby stimulate its primer recognition and DNA synthesis.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

POLE1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using POLE1 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms P
0.1 ml / €325.00
  OriGene Technologies, Inc.

POLE1 antibody

Immunofluorescence of purified MaxPab antibody to POLE on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

POLE1 antibody

Immunofluorescence of purified MaxPab antibody to POLE on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

POLE1 antibody

POLE1 Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

POLE1 antibody

Immunoprecipitation/Western blot analysis of POLE expression in 293 cells. Immunoprecipitation ( denatured verified ) using 2 µl/mg protein lysate. Use Protein G. Mouse IgG1 93H3A Bov, Hu, Mky, Ms IP
0.1 mg / €820.00
  Abnova Taiwan Corp.

POLE1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using POLE1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P
50 µg / €205.00
  Assay Biotech

POLE1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using POLE1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P
0.1 mg / €310.00
  Assay Biotech

POLE1 antibody

POLE1 Mouse IgG2a 3C5.1 Biotin Hu, Mky, Ms WB
50 µl / €260.00
  Novus Biologicals Inc.

POLE1 antibody

POLE1 Mouse IgG2a 3C5.1 DyLight488 Hu, Mky, Ms WB
50 µl / €270.00
  Novus Biologicals Inc.

POLE1 antibody

POLE1 Mouse IgG2a 3C5.1 HRP Hu, Mky, Ms WB
50 µl / €270.00
  Novus Biologicals Inc.

POLE1 antibody

POLE1 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €360.00
  Novus Biologicals Inc.

POLE1 antibody

POLE1 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

POLE1

POLE1 Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

POLE 293T Cell Transient Overexpression Lysate(Denatured)

POLE 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

14 Item(s)

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