POLR3C / RPC3 antibody

Principal name

POLR3C / RPC3 antibody

Alternative names for POLR3C / RPC3 antibody

RPC62, DNA-directed RNA polymerase III subunit RPC3, RNA polymerase III subunit C3, RNA polymerase III 62 kDa subunit

SwissProt ID

P32349 (Yeast), Q2TBL4 (Bovin), Q5XIL3 (Rat), Q7ZUX1 (Danre), Q9BUI4 (Human), Q9C106 (Schpo), Q9D483 (Mouse)

Gene ID

10623 (POLR3C), 74414 (Polr3c), 310685

Available reactivities

Hu (Human), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Ms (Mouse), Rb (Rabbit), Ye (Yeast)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P)

Background of POLR3C / RPC3 antibody

D-dependent R polymerase catalyzes the transcription of D into R using the four ribonucleoside triphosphates as substrates. POLR3C is a specific core component of R polymerase III which synthesizes small Rs, such as 5S rR and tRs. POLR3C may direct with other members of the subcomplex R Pol III binding to the TFIIIB-D complex via the interactions between TFIIIB and POLR3F. POLR3C may be involved either in the recruitment and stabilization of the subcomplex within R polymerase III, or in stimulating catalytic functions of other subunits during initiation. POLR3C plays a key role in sensing and limiting infection by intracellular bacteria and D viruses.POLR3C acts as nuclear and cytosolic D sensor involved in inte immune response. POLR3C can sense non-self dsD that serves as template for transcription into dsR. The non-self R polymerase III transcripts, such as Epstein-Barr virus-encoded Rs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

POLR3C / RPC3 antibody

  POLR3C (RPC62) mouse monoclonal antibody, clone OTI2H1 (formerly 2H1)  
Immunohistochemical staining of paraffin-embedded Human bladder tissue within the normal limits using anti-POLR3C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA505106) Mouse IgG1 OTI2H1 Purified Hu ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

POLR3C / RPC3 antibody

  Rabbit polyclonal RPC3 antibody  
Western blot analysis of extracts from K562 cells, CoLo205 cells and HuvEc cells, using RPC3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

POLR3C / RPC3 antibody

  Rabbit Polyclonal Anti-POLR3C Antibody  
WB Suggested Anti-POLR3C Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 12500; Positive Control: 293T cell lysatePOLR3C is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ye WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

POLR3C - human gene knockout kit via CRISPR

POLR3C - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

POLR3C - human gene knockout kit via CRISPR

POLR3C - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

POLR3C - human gene knockout kit via CRISPR

POLR3C - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

POLR3C - human gene knockout kit via CRISPR

POLR3C - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Polr3c - mouse gene knockout kit via CRISPR

Polr3c - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Polr3c - mouse gene knockout kit via CRISPR

Polr3c - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Polr3c - mouse gene knockout kit via CRISPR

Polr3c - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Polr3c - mouse gene knockout kit via CRISPR

Polr3c - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

POLR3C / RPC3

  Recombinant protein of human polymerase (RNA) III (DNA directed) polypeptide C (62kD) (POLR3C)  
POLR3C / RPC3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, POLR3C (mGFP-tagged) - Human polymerase (RNA) III (DNA directed) polypeptide C (62kD) (POLR3C), 200 uL, >10^7 TU/mL

Lenti ORF particles, POLR3C (mGFP-tagged) - Human polymerase (RNA) III (DNA directed) polypeptide C (62kD) (POLR3C), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, POLR3C (Myc-DDK tagged) - Human polymerase (RNA) III (DNA directed) polypeptide C (62kD) (POLR3C) , 200 uL, >10^7 TU/mL

Lenti ORF particles, POLR3C (Myc-DDK tagged) - Human polymerase (RNA) III (DNA directed) polypeptide C (62kD) (POLR3C) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Polr3c (GFP-tagged) - Mouse polymerase (RNA) III (DNA directed) polypeptide C (Polr3c), 200 uL, >10^7 TU/mL

Lenti ORF particles, Polr3c (GFP-tagged) - Mouse polymerase (RNA) III (DNA directed) polypeptide C (Polr3c), 200 uL, >10^7 TU/mL  
200 µl / €1,160.00
  OriGene Technologies, Inc.

Lenti ORF particles, Polr3c (Myc-DDK-tagged) - Mouse polymerase (RNA) III (DNA directed) polypeptide C (Polr3c), 200 uL, >10^7 TU/mL

Lenti ORF particles, Polr3c (Myc-DDK-tagged) - Mouse polymerase (RNA) III (DNA directed) polypeptide C (Polr3c), 200 uL, >10^7 TU/mL  
200 µl / €1,040.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Polr3c (GFP-tagged ORF) - Rat polymerase (RNA) III (DNA directed) polypeptide C (62kD) (Polr3c), 200 uL, >10^7 TU/mL

Lenti ORF particles, Polr3c (GFP-tagged ORF) - Rat polymerase (RNA) III (DNA directed) polypeptide C (62kD) (Polr3c), 200 uL, >10^7 TU/mL  
200 µl / €1,160.00
  OriGene Technologies, Inc.

Lenti ORF particles, Polr3c (Myc-DDK-tagged ORF) - Rat polymerase (RNA) III (DNA directed) polypeptide C (62kD) (Polr3c), 200 uL, >10^7 TU/mL

Lenti ORF particles, Polr3c (Myc-DDK-tagged ORF) - Rat polymerase (RNA) III (DNA directed) polypeptide C (62kD) (Polr3c), 200 uL, >10^7 TU/mL  
200 µl / €1,041.00
  OriGene Technologies, Inc.

18 Item(s)

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