POLR3C / RPC3 antibody

Principal name

POLR3C / RPC3 antibody

Alternative names for POLR3C / RPC3 antibody

RPC62, DNA-directed RNA polymerase III subunit RPC3, RNA polymerase III subunit C3, RNA polymerase III 62 kDa subunit

SwissProt ID

P32349 (Yeast), Q2TBL4 (Bovin), Q5XIL3 (Rat), Q7ZUX1 (Danre), Q9BUI4 (Human), Q9C106 (Schpo), Q9D483 (Mouse)

Gene ID

10623 (POLR3C)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ye (Yeast)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP)

Background of POLR3C / RPC3 antibody

D-dependent R polymerase catalyzes the transcription of D into R using the four ribonucleoside triphosphates as substrates. POLR3C is a specific core component of R polymerase III which synthesizes small Rs, such as 5S rR and tRs. POLR3C may direct with other members of the subcomplex R Pol III binding to the TFIIIB-D complex via the interactions between TFIIIB and POLR3F. POLR3C may be involved either in the recruitment and stabilization of the subcomplex within R polymerase III, or in stimulating catalytic functions of other subunits during initiation. POLR3C plays a key role in sensing and limiting infection by intracellular bacteria and D viruses.POLR3C acts as nuclear and cytosolic D sensor involved in inte immune response. POLR3C can sense non-self dsD that serves as template for transcription into dsR. The non-self R polymerase III transcripts, such as Epstein-Barr virus-encoded Rs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

POLR3C / RPC3 antibody

Immunohistochemical staining of paraffin-embedded Human bladder tissue within the normal limits using anti-POLR3C mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA505106) Mouse IgG1 OTI2H1 Purified Hu ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

POLR3C / RPC3 antibody

Immunofluorescence of purified MaxPab antibody to POLR3C on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu, Rt E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

POLR3C / RPC3 antibody

Western blot analysis of extracts from K562 cells, CoLo205 cells and HuvEc cells, using RPC3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

POLR3C / RPC3 antibody

WB Suggested Anti-POLR3C Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 12500; Positive Control: 293T cell lysatePOLR3C is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ye WB
50 µg / €325.00
  OriGene Technologies, Inc.

POLR3C / RPC3 antibody

Immunofluorescence of purified MaxPab antibody to POLR3C on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

POLR3C / RPC3 antibody

Immunofluorescence of purified MaxPab antibody to POLR3C on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

POLR3C / RPC3 antibody

POLR3C / RPC3 Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

POLR3C / RPC3 antibody

POLR3C / RPC3 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

POLR3C / RPC3 antibody

Western blot analysis of POLR3C expression in HeLa (A) whole cell lysates. Rabbit Aff - Purified Hu IP, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

POLR3C / RPC3 antibody

Western blot analysis of POLR3C expression in HeLa (A) whole cell lysates. Rabbit Aff - Purified Hu IP, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

POLR3C / RPC3 antibody

Western blot analysis of POLR3C expression in HeLa (A) whole cell lysates. Rabbit Aff - Purified Hu IP, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

POLR3C / RPC3 antibody

Western Blot: RPC62 Antibody [NBP1-71821]-Whole cell lysate from HeLa (H; 50 mcg for WB; 1 mg for IP, 20% of IP loaded), 293T (5, 15, and 50 mcg for WB) and mouse NIH3T3 (M; 50 mcg) cells.   Affinity purified rabbit anti-RPC3 antibody used for WB at 0.4 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate.  RPC3 was also immunoprecipitated by rabbit anti-RPC3 antibody NBP1-71820, which recognizes an upstream epitope. Rabbit Aff - Purified Hu, Ms WB
0.1 mg / €440.00
  Novus Biologicals Inc.

POLR3C / RPC3 antibody

Immunohistochemistry-Paraffin: RPC62 Antibody [NBP1-87110] - Immunohistochemical staining of human adrenal gland shows moderate cytoplasmic and nuclear positivity in cortical cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

POLR3C / RPC3 antibody

Immunohistochemistry-Paraffin: RPC62 Antibody [NBP1-87111] - Immunohistochemical staining of human colon shows strong cytoplasmic positivity in goblet cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

POLR3C / RPC3

POLR3C / RPC3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

POLR3C / RPC3

POLR3C / RPC3 Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

POLR3C / RPC3

POLR3C / RPC3 Human Purified
10 µg / €380.00
  Abnova Taiwan Corp.

POLR3C / RPC3

POLR3C / RPC3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

POLR3C / RPC3

POLR3C / RPC3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

POLR3C / RPC3

POLR3C / RPC3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

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