POLR3G antibody

Principal name

POLR3G antibody

Alternative names for POLR3G antibody

RNA polymerase III subunit C7, RPC7, RPC32, DNA-directed RNA polymerase III subunit RPC7, DNA-directed RNA polymerase III subunit G, RNA polymerase III 32 kDa subunit

SwissProt ID

O15318 (Human), P17890 (Yeast), Q6NXY9 (Mouse), Q8WZJ8 (Schpo)

Gene ID

10622 (POLR3G)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB)

Background of POLR3G antibody

D-dependent R polymerase catalyzes the transcription of D into R using the four ribonucleoside triphosphates as substrates. POLR3G is a specific peripheric component of R polymerase III which synthesizes small Rs, such as 5S rR and tRs. It may direct with other members of the RPC3/POLR3C-RPC6/POLR3F-RPC7/POLR3G subcomplex R Pol III binding to the TFIIIB-D complex via the interactions between TFIIIB and POLR3F. It may be involved either in the recruitment and stabilization of the subcomplex within R polymerase III, or in stimulating catalytic functions of other subunits during initiation. POLR3G plays a key role in sensing and limiting infection by intracellular bacteria and D viruses. POLR3G acts as nuclear and cytosolic D sensor involved in inte immune response. POLR3G can sense non-self dsD that serves as template for transcription into dsR. The non-self R polymerase III transcripts, such as Epstein-Barr virus-encoded Rs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

POLR3G antibody

  Rabbit Polyclonal Anti-POLR3G Antibody  
Host: Rabbit; Target Name: POLR3G; Sample Tissue: COLO205 Whole Cell lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

POLR3G - human gene knockout kit via CRISPR

POLR3G - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

POLR3G - human gene knockout kit via CRISPR

POLR3G - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

POLR3G - human gene knockout kit via CRISPR

POLR3G - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

POLR3G - human gene knockout kit via CRISPR

POLR3G - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

5 Item(s)

per page
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