PPAPDC1A antibody

Principal name

PPAPDC1A antibody

Alternative names for PPAPDC1A antibody

DPPL2, PPAPDC1, Phosphatidate phosphatase PPAPDC1A, Phosphatidic acid phosphatase type 2 domain-containing protein 1A

SwissProt ID

Q0VBU9 (Mouse), Q5VZY2 (Human)

Gene ID

196051 (PPAPDC1A)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of PPAPDC1A antibody

Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide(NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. PPAPDC1A is preferentially expressed in endothelial cells. Studies of PPAPDC1A and PAP activity suggest that they may play a role in angiogenesis.

General readings

Rose, J. Phd, et al. Mol. Med. (2010) In press.
Takeuchi, M., et al. Gene 399(2):174-180 (2007).

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PPAPDC1A antibody

Western blot analysis of PPAPDC1A in human brain tissue lysate with PPAPDC1A antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PPAPDC1A Control Peptide

PPAPDC1A
50 µg / €160.00
  Acris Antibodies GmbH

PPAPDC1A (N-term) antibody

Formalin fixed and paraffin embedded human brain tissue reacted with PPAPDC1A Antibody (N-term) Cat.-No AP53406PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PPAPDC1A antibody

PPAPDC1A Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PPAPDC1A overexpression lysate

PPAPDC1A overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

5 Item(s)

per page
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