PPAPDC2 antibody

Principal name

PPAPDC2 antibody

Alternative names for PPAPDC2 antibody

Presqualene diphosphate phosphatase, Phosphatidic acid phosphatase type 2 domain-containing protein 2, PPAP2 domain-containing protein 2

SwissProt ID

P82891 (Drome), Q58DI5 (Bovin), Q5TZ07 (Danre), Q66H88 (Rat), Q8IY26 (Human), Q9D4F2 (Mouse)

Gene ID

403313 (PPAPDC2), 74411 (Ppapdc2), 619549

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of PPAPDC2 antibody

Upon cell activation Presqualene diphosphate (PSDP)2, a bioactive lipid, rapidly remodels to presqualene monophosphate (PSMP). A newly identified and characterized phosphatase (phosphatidic acid phosphatase domain containing 2 (PPAPDC2)) has recent;y been shown to convert PSDP to PSMP. Unlike the related polyisoprenyl phosphate farnesyl diphosphate (FDP), PSDP has been shown not to be a substrate for type 2 lipid phosphate phosphohydrolases. PSDP phosphatase activity has been identified in activated human neutrophil (PMN) extracts. Recombinant PPAPDC2 displays diphosphate phosphatase activity with substrate preference for PSDP > FDP phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and optimal at pH 7.0 - 8.0. PPAPDC2 mRNA has been detected in human PMN, and is widely expressed in human tissues. PPAPDC2 expressed in human PMN is first lipid phosphate phosphohydrolase identified for PSDP. The regulation of this enzymes activity has important implications for PMN activation in innate immunity.

19 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PPAPDC2 antibody

  Rabbit Polyclonal PPAPDC2 Antibody  
Western blot analysis of PPAPDC2 in Raji cell lysate with PPAPDC2 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PPAPDC2 antibody

  Rabbit Polyclonal Anti-PPAPDC2 Antibody  
WB Suggested Anti-PPAPDC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human heart Rabbit IgG Purified Hu, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

PPAPDC2 antibody

  Rabbit Polyclonal Anti-PPAPDC2 Antibody  
WB Suggested Anti-PPAPDC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Hela cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

PPAPDC2 antibody

PPAPDC2 Rabbit Aff - Purified Hu WB
10 Blots / €490.00
  Acris Antibodies GmbH

PPAPDC2 (C-term) antibody

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

PPAPDC2 - human gene knockout kit via CRISPR

PPAPDC2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PPAPDC2 - human gene knockout kit via CRISPR

PPAPDC2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PPAPDC2 - human gene knockout kit via CRISPR

PPAPDC2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PPAPDC2 - human gene knockout kit via CRISPR

PPAPDC2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ppapdc2 - mouse gene knockout kit via CRISPR

Ppapdc2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Ppapdc2 - mouse gene knockout kit via CRISPR

Ppapdc2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ppapdc2 - mouse gene knockout kit via CRISPR

Ppapdc2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ppapdc2 - mouse gene knockout kit via CRISPR

Ppapdc2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PPAPDC2 overexpression lysate

PPAPDC2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PPAPDC2 (mGFP-tagged) - Human phosphatidic acid phosphatase type 2 domain containing 2 (PPAPDC2), 200 uL, >10^7 TU/mL

Lenti ORF particles, PPAPDC2 (mGFP-tagged) - Human phosphatidic acid phosphatase type 2 domain containing 2 (PPAPDC2), 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, PPAPDC2 (Myc-DDK tagged) - Human phosphatidic acid phosphatase type 2 domain containing 2 (PPAPDC2) , 200 uL, >10^7 TU/mL

Lenti ORF particles, PPAPDC2 (Myc-DDK tagged) - Human phosphatidic acid phosphatase type 2 domain containing 2 (PPAPDC2) , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ppapdc2 (GFP-tagged) - Mouse phosphatidic acid phosphatase type 2 domain containing 2 (Ppapdc2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ppapdc2 (GFP-tagged) - Mouse phosphatidic acid phosphatase type 2 domain containing 2 (Ppapdc2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ppapdc2 (GFP-tagged ORF) - Rat phosphatidic acid phosphatase type 2 domain containing 2 (Ppapdc2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ppapdc2 (GFP-tagged ORF) - Rat phosphatidic acid phosphatase type 2 domain containing 2 (Ppapdc2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ppapdc2 (Myc-DDK-tagged ORF) - Rat phosphatidic acid phosphatase type 2 domain containing 2 (Ppapdc2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ppapdc2 (Myc-DDK-tagged ORF) - Rat phosphatidic acid phosphatase type 2 domain containing 2 (Ppapdc2), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

19 Item(s)

per page
  • LinkedIn