PPAPDC2 antibody

Principal name

PPAPDC2 antibody

Alternative names for PPAPDC2 antibody

Presqualene diphosphate phosphatase, Phosphatidic acid phosphatase type 2 domain-containing protein 2, PPAP2 domain-containing protein 2

SwissProt ID

P82891 (Drome), Q58DI5 (Bovin), Q5TZ07 (Danre), Q66H88 (Rat), Q8IY26 (Human), Q9D4F2 (Mouse)

Gene ID

403313 (PPAPDC2)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of PPAPDC2 antibody

Upon cell activation Presqualene diphosphate (PSDP)2, a bioactive lipid, rapidly remodels to presqualene monophosphate (PSMP). A newly identified and characterized phosphatase (phosphatidic acid phosphatase domain containing 2 (PPAPDC2)) has recent;y been shown to convert PSDP to PSMP. Unlike the related polyisoprenyl phosphate farnesyl diphosphate (FDP), PSDP has been shown not to be a substrate for type 2 lipid phosphate phosphohydrolases. PSDP phosphatase activity has been identified in activated human neutrophil (PMN) extracts. Recombinant PPAPDC2 displays diphosphate phosphatase activity with substrate preference for PSDP > FDP phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and optimal at pH 7.0 - 8.0. PPAPDC2 mRNA has been detected in human PMN, and is widely expressed in human tissues. PPAPDC2 expressed in human PMN is first lipid phosphate phosphohydrolase identified for PSDP. The regulation of this enzymes activity has important implications for PMN activation in innate immunity.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PPAPDC2 antibody

Western blot analysis of PPAPDC2 in Raji cell lysate with PPAPDC2 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PPAPDC2 antibody

WB Suggested Anti-PPAPDC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human heart Rabbit IgG Purified Hu, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

PPAPDC2 antibody

WB Suggested Anti-PPAPDC2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Hela cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

PPAPDC2 antibody

PPAPDC2 Rabbit Aff - Purified Hu WB
10 Blots / €480.00
  Acris Antibodies GmbH

PPAPDC2 (C-term) antibody

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PPAPDC2 Control Peptide

PPAPDC2
50 µg / €160.00
  Acris Antibodies GmbH

PPAPDC2 antibody

Human Heart; WB Suggested Anti-PPAPDC2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human heart; PPAPDC2 antibody - N-terminal region (ARP55973_P050) in Human Heart cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

PPAPDC2 antibody

Human HeLa; WB Suggested Anti-PPAPDC2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Hela cell lysate; PPAPDC2 antibody - N-terminal region (ARP55974_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

PPAPDC2 antibody

Western Blot: PPAPDC2 Antibody [NBP1-60021] - This Anti-PPAPDC2 antibody was used in Western Blot of Fetal Heart tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

PPAPDC2 antibody

Western Blot: PPAPDC2 Antibody [NBP1-60022] - This Anti-PPAPDC2 antibody was used in Western Blot of Hela     tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

PPAPDC2 antibody

Western Blot: PDP1/PPAPDC2   Antibody [NBP1-76245] - Analysis of PDP1/PPAPDC2  in Raji cell lysate with PDP1/PPAPDC2  antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

PPAPDC2 antibody

Immunohistochemistry-Paraffin: PPAPDC2 Antibody [NBP1-83443] - Immunohistochemical staining of human urinary bladder shows strong cytoplasmic positivity in urothelial cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

PPAPDC2 overexpression lysate

PPAPDC2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

13 Item(s)

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