PPP1R1A antibody

Principal name

PPP1R1A antibody

Alternative names for PPP1R1A antibody

IPP1, IPP-1, Protein phosphatase 1 regulatory subunit 1A, Protein phosphatase inhibitor 1

SwissProt ID

P01099 (Rabit), P19103 (Rat), Q13522 (Human), Q8WMS3 (Canfa), Q9ERT9 (Mouse)

Gene ID

5502 (PPP1R1A)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chimp (Chimpanzee), Eq (Equine), Mky (Monkey), Xen (Xenopus)

Available hosts

Rabbit

Available applications

Flow Cytometry (F), Paraffin Sections (P), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of PPP1R1A antibody

The inhibitor of protein phosphatase 1 (IPP-1, I-1) is an endogenous inhibitor of protein phophastase 1 (PP-1), a signal transducer in many cellular pathways. IPP-1 is a member of heat-stable PP1 inhibitory subunits, which includes DARPP-32, (a homologue of IPP-1) and IPP-2. First discovered in rabbit skeletal muscle, IPP-1 is expressed in various mammalian tissues. IPP-1 inhibition of PP-1 is controlled through phosphorylation at Thr35 by cAMP-dependent protein kinase and a tetra-peptide consensus motif in various PP-1 binding proteins (1). IPP-1 is a hormonal control in muscle contraction, pituitary cell growth, synaptic plasticity by neurotransmitters, and glycogen metabolism (2). In vivo, IPP-1 is phosphorylated at Ser-67 by NCLK, which also initiates inhibition of PP-1 by IPP-1 (3). Triggered by increase in calcium level, IPP-1 is inactivated by PP2B through de-phosphorylation (4).

General readings

Weiser DC., et al. (2004), J. Biol. Chem. Nov 19;279(47):48904-14.
Rodriguez P., et al. (2006), J. Biol. Chem. Dec 15;281(50):38599-608.

11 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PPP1R1A (50-100) antibody

Formalin-Fixed Paraffin-Embedded Human Kidney stained with PPP1R1A Antibody Cat.-No AP08281PU-N at 10 µg/ml after heat-induced antigen retrieval. Rabbit IgG Aff - Purified Bov, Can, Eq, Hu, Mky, Ms, Rt, Xen P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PPP1R1A antibody

Western blot analysis of IPP1 expression in MCF7 (A); SP2/0 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Can, Hu, Mky, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

PPP1R1A antibody

Western blot analysis of IPP1 expression in MCF7 (A); SP2/0 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Can, Hu, Mky, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

PPP1R1A antibody

Western blot analysis of IPP1 expression in MCF7 (A); SP2/0 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Can, Hu, Mky, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

PPP1R1A (N-term) antibody

Immunohistochemistry: IPP-1 Antibody (EP902Y) [NB110-57125] - Immunohistochemical analysis of paraffin-embedded human normal brain tissue using anti_IPP1. (cat. # 110-57125). Rabbit IgG EP902Y Supernatant Hu, Ms, Rt F, IP, P, WB
0.1 ml / €480.00
  Novus Biologicals Inc.

PPP1R1A antibody

PPP1R1A Rabbit Bov, Can, Eq, Hu, Mky, Ms, Rt, Xen C, WB
50 µg / €480.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PPP1R1A

PPP1R1A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PPP1R1A

PPP1R1A Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €299.00
  OriGene Technologies, Inc.

PPP1R1A (1-171, His-tag)

PPP1R1A Human Purified ≥ 90 E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

PPP1R1A (1-171, His-tag)

PPP1R1A Human Purified ≥ 90 E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

PPP1R1A

PPP1R1A Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

11 Item(s)

per page
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