PPP1R2 / IPP2 antibody

Principal name

PPP1R2 / IPP2 antibody

Alternative names for PPP1R2 / IPP2 antibody

Protein phosphatase inhibitor 2, IPP-2

SwissProt ID

P11845 (Rabit), P41236 (Human), P50411 (Rat), Q3SZX2 (Bovin), Q9DCL8 (Mouse)

Gene ID

5504 (PPP1R2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), EPair for Elisa (EPair)

Background of PPP1R2 / IPP2 antibody

Inhibitor-2 (I-2) exists as a heterodimer with protein phosphatase type-1 (PP1), termed MgATP-dependent phosphatase. I-2 binds and forms an inactive complex with PP1 in its unphosphorylated state. This complex is activated through a series of phosphorylations on serine and threonine residues in I-2 that increases phosphatase activity. Multiple kinases have been implicated in phosphorylation of I-2 at threonine 72, namely GSK-3, cdc2 and ERK1. Casein kinase II phosphorylates I-2 at serine residues, which in turn enhances threonine phosphorylation by GSK-3. Recent evidence has shown that phosphorylation at threonine 72 peaks during prophase of the cell cycle and is localized in the centrosomes. The I-2/PP1 complex also binds neurabin and the kinases Nek2, KPI-2, and Aurora-A. Regulation of I-2/PP1 has been shown to be important in cell cycle, gene expression, ion gating, and neuromodulation.

General readings

Wang, W., et al. Mol. Biol. Cell 19(11):4852-4862 (2008).
Wang, W., et al. BMC Cell Biol. 9, 62 (2008).
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109 (2007).
Lamesch, P., et al. Genomics 89(3):307-315 (2007).
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PPP1R2 / IPP2 antibody

Western blot analysis of extracts from COLO cells, HepG2 cells and HUVEC cells, using PPP1R2 (Ab-44) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PPP1R2 / IPP2 antibody

Western blot analysis of extracts from Jurkat cells, using PPP1R2 (Ab-120/121) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt
0.1 ml / €325.00
  OriGene Technologies, Inc.

PPP1R2 / IPP2 antibody

Western blot analysis on Jurkat cell lysate using PPP1R2 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PPP1R2 / IPP2 antibody

Western blot analysis of PPP1R2 expression in Jurkat cells Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PPP1R2 / IPP2 antibody

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 2E9 Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

PPP1R2 / IPP2 (Center) antibody

Western blot analysis of PPP1R2 Antibody (Center) Cat.-No AP53416PU-N in Hela cell line lysates (35ug/lane). This demonstrates the PPP1R2 antibody detected the PPP1R2 protein (arrow) Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PPP1R2 / IPP2 antibody

PPP1R2 polyclonal antibody (A01), Lot # 060524JCS1 Western Blot analysis of PPP1R2 expression in MES-SA/Dx5 ( Cat # L021V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

PPP1R2 / IPP2 antibody

Western Blot analysis of PPP1R2 expression in transfected 293T cell line (H00005504-T02) by PPP1R2 MaxPab polyclonal antibody.

Lane 1: PPP1R2 transfected lysate(23.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PPP1R2 / IPP2 antibody

Immunoperoxidase of monoclonal antibody to PPP1R2 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml] Mouse IgG2a 2E9 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PPP1R2 / IPP2 pSer120/121 antibody

Immunohistochemistry analysis of paraffin-embedded human heart, using PPP1R2 (Phospho-Ser120+Ser121) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
50 µg / €205.00
  Assay Biotech

PPP1R2 / IPP2 pSer120/121 antibody

Immunohistochemistry analysis of paraffin-embedded human heart, using PPP1R2 (Phospho-Ser120+Ser121) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €310.00
  Assay Biotech

PPP1R2 / IPP2 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PPP1R2 (Ab-120/121) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €205.00
  Assay Biotech

PPP1R2 / IPP2 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PPP1R2 (Ab-120/121) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €310.00
  Assay Biotech

PPP1R2 / IPP2 antibody

Western blot analysis of extracts from HuvEc/HepG2/COLO cells, using PPP1R2 (Ab-44) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

PPP1R2 / IPP2 antibody

Western blot analysis of extracts from HuvEc/HepG2/COLO cells, using PPP1R2 (Ab-44) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

PPP1R2 / IPP2 (N-term) antibody

Human THP-1; WB Suggested Anti-PPP1R2 Antibody. . Titration: 1.0 ug/ml. . Positive Control: THP-1 Whole Cell; PPP1R2 antibody - N-terminal region (ARP61382_P050) in Human THP-1 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

PPP1R2 / IPP2 antibody

PPP1R2 / IPP2 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

PPP1R2 / IPP2 antibody

PPP1R2 / IPP2 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €290.00
  Novus Biologicals Inc.

PPP1R2 / IPP2 antibody

PPP1R2 / IPP2 Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PPP1R2 / IPP2

PPP1R2 / IPP2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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