Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)
Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB)
Background of PPP2R3A / PPP2R3 antibody
This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly med type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Altertive splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Jun 2010].
Immunohistochemistry: AP08886PU-N PPP2R3A antibody staining of Formalin-Fixed, Paraffin-Embedded Human Brain, cerebellum at 5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
PPP2R3A antibody [C2C3], C-term detects PPP2R3A protein at cytoplasm by immunofluorescent analysis.Sample: U87-MG cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: PPP2R3A protein stained by PPP2R3A antibody [C2C3], C-term (GTX114655) diluted at 1:500.Blue: Hoechst 33342 staining.