PPP4C antibody

Principal name

PPP4C antibody

Alternative names for PPP4C antibody

PPP4, PP4C, PPX, PP-X, Protein phosphatase X, Serine/threonine-protein phosphatase 4 catalytic subunit

SwissProt ID

A6H772 (Bovin), O76932 (Drome), P11084 (Rabit), P32345 (Yeast), P60510 (Human), P97470 (Mouse), Q5BJ92 (Rat), Q6IP91 (Xenla)

Gene ID

5531 (PPP4C)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Rb (Rabbit), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig)

Available hosts

Mouse, Rabbit, Sheep, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Frozen Sections (C), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Dot blot (Dot)

Background of PPP4C antibody

Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.

General readings

Cohen P T., et al. (1993) Biochem Soc Trans. 21:884-888.Mumby M C., et al. (1993) Phys Rev. 73:673-699.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PPP4C antibody

Western blot analysis of extracts of various cell lines, using PPP4C antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

PPP4C (C-term) antibody

TA305920 (0.3 ug/ml) staining of Rat Spleen (A) and Lung (B) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Rb, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PPP4C antibody

WB Suggested Anti-PPP4C Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Muscle Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PPP4C antibody

Western blot detection of Protein Phosphatase 4C in Hela and Jurkat cell lysates using Protein Phosphatase 4C mouse mAb (1:200 diluted).Predicted band size: 34KDa.Observed band size: 34KDa. Mouse IgG2a 2F11-D10-G4 Purified ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PPP4C antibody

PP X/C antibody western blot of total bovine testes homogenate. (+) indicates presence of specific blocking peptide of control peptide (-). Rabbit IgG Purified Bov, Hu, Ms, Rt C, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

PPP4C antibody

PP X/C interior antibody western blot of total bovine testes homogenate. (+) indicates presence of specific blocking peptide of control peptide (-). Sheep IgG Purified Bov, Hu, Ms, Rt C, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

PPP4C antibody

Figure 2. Staining PPP4C in Prostate by Immunohistochemistry using Formalin-Fixed Paraffin-Embedded (FFPE) tissue. Rabbit Purified Bov, Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PPP4C (290-301) antibody

Human Small Intestine (formalin-fixed, paraffin-embedded) stained with PPP4C antibody AP22586PU-N followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Fi, Hu, Insect, Mky, Ms, Op, Pl, Platypus, Prim, Rb, Rt, Xen E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PPP4C antibody

PPP4C Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

PPP4C antibody

PPP4C Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

PPP4C antibody

PPP4C Mouse IgG2a 1E8 Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PPP4C antibody

PPP4C Rabbit IgG Bov, Hu, Ms, Rb, Rt ICC/IF, WB
0.1 mg / €560.00
  Abnova Taiwan Corp.

PPP4C antibody

PPP4C polyclonal antibody ( Cat # PAB14146 ) ( 0.3µg/ml ) staining of HEK293 lysate ( 35µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

PPP4C antibody

Human Muscle; WB Suggested Anti-PPP4C Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Muscle; PPP4C antibody - middle region (ARP58516_P050) in Human Muscle cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rb, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

PPP4C antibody

Western Blot: PPP4C Antibody [NBP1-31117] - Western blot analysis of PPP4C Antibody on: A:A431 B:HeLa S3 12% SDS PAGE diluted at 1:500 Rabbit IgG Hu Dot, ICC/IF, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

PPP4C antibody

Immunohistochemistry-Paraffin: PPP4C Antibody [NBP1-50579] - Human Small Intestine (formalin-fixed, paraffin-embedded) stained with PPP4C antibody followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Can, Hu, Rt E, P, WB
50 µg / €480.00
  Novus Biologicals Inc.

PPP4C antibody

PPP4C Goat Aff - Purified Can, Hu, Rb, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PPP4C (full length, N-term HIS tag)

PPP4C Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

PPP4C (1-307, His-tag)

PPP4C Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

PPP4C (1-307, His-tag)

PPP4C Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

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