PRC1 antibody

Principal name

PRC1 antibody

Alternative names for PRC1 antibody

ASE1, Protein regulator of cytokinesis 1

SwissProt ID

O43663 (Human), Q99K43 (Mouse)

Gene ID

9055 (PRC1), 233406 (Prc1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PRC1 antibody

PRC1 (also known as protein regulator of cytokinesis 1 and mitotic spindle-associated CDK substrate) is a member of the MAP65/ASE1 family with a molecular weight of approximately 72 kD. PRC1 localization changes with cell-cycle position and can be found in the nucleus, the mitotic spindle, and the cell mid-body. PRC1 is a mitotic spindle-associated CDK substrate protein required for cytokinesis and maintenance of the spindle midzone. PRC1 can be modified by phosphorylation and has been shown to interact with Cdc2 and Cdk2.
Structure: MAP65/ASE1; approximately 72 kD.
Distribution: Cell cycle-dependent; nuclear, mitotic spindle, cell mid-body.
Function: Mitotic spindle-associated CDK substrate protein required for cytokinesis, maintains the spindle midzone.
Modification: Phosphorylation.
nteraction: Cdc2, Cdk2

General readings

Jiang W, Jimenez G, Wells NJ, et al. PRC1: a human mitotic spindle-associated Cdk substrate protein required for cytokinesis. Mol. Cell 1998; 2:877-85.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PRC1 (Center) antibody

  Rabbit Polyclonal PRC1 Antibody  
Western blot analysis of PRC1 in human skeletal muscle tissue lysate with Prc1 antibody at (A) 0.5 ug/ml and (B) 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PRC1 (1-150) antibody

  Mouse Monoclonal anti-PRC1 Antibody  
Hela cell extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal antibody reactive against PRC1 (clone 6G2). Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system. Mouse IgG2b 6G2 Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

Prc1 - mouse gene knockout kit via CRISPR

Prc1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Prc1 - mouse gene knockout kit via CRISPR

Prc1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Prc1 - mouse gene knockout kit via CRISPR

Prc1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Prc1 - mouse gene knockout kit via CRISPR

Prc1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PRC1 (transcript variant 1)

  Recombinant protein of human protein regulator of cytokinesis 1 (PRC1), transcript variant 1  
PRC1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

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