PRC1 antibody

Principal name

PRC1 antibody

Alternative names for PRC1 antibody

ASE1, Protein regulator of cytokinesis 1

SwissProt ID

O43663 (Human), Q99K43 (Mouse)

Gene ID

9055 (PRC1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP)

Background of PRC1 antibody

Novel human protein Protein regulator of cytokinesis 1 (PRC1) is involved in cytokinesis. PRC1 is a good substrate for several CDKs in vitro and is phosphorylated in vivo at sites that are phosphorylated by CDK in vitro, strongly suggesting that PRC1 is an in vivo CDK substrate. PRC1 protein levels are high during S and G2/M and drop dramatically after cells exit mitosis and enter G1. PRC1 is a nuclear protein in interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis (1). PRC1, a mitotic spindle-associated Cdk substrate that is essential to cell cleavage, is a microtubule binding and bundling protein both in vivo and in vitro. Over expression of PRC1 extensively bundles interphase microtubules, but does not affect early mitotic spindle organization (2). PRC1 has been shown to down-regulate the GAP activity of MgcRac-GAP during the metaphase and thereby contributes to the correct formation of the spindle (3).

General readings

Jiang W, Jimenez G, Wells NJ, et al. PRC1: a human mitotic spindle-associated Cdk substrate protein required for cytokinesis. Mol. Cell 1998; 2:877-85.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PRC1 (Center) antibody

Western blot analysis of PRC1 in human skeletal muscle tissue lysate with Prc1 antibody at (A) 0.5 ug/ml and (B) 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PRC1 (1-150) antibody

Hela cell extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal antibody reactive against PRC1 (clone 6G2). Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system. Mouse IgG2b 6G2 Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PRC1 (1-150) antibody

Hela cell extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal antibody reactive against PRC1 (clone 6G2). Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system. Mouse IgG2b 6G2 Purified Hu WB
25 µg / €210.00
  Acris Antibodies GmbH

PRC1 (Center) Control Peptide

PRC1
50 µg / €160.00
  Acris Antibodies GmbH

PRC1 antibody

PRC1 Mouse IgG1 3E3-1G1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PRC1 antibody

PRC1 Mouse IgG1 3B10-1F9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PRC1 antibody

PRC1 Mouse IgG2b 16F2 Purified Hu, Ms, Rt ICC/IF, IP, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

PRC1 antibody

Hela cell extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal antibody reactive against PRC1 (clone 6G2). Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system Mouse IgG2b 6G2 Aff - Purified Hu WB
0.1 mg / €400.00
  Novus Biologicals Inc.

PRC1 antibody

Immunohistochemistry: PRC1 Antibody (EP1513Y) [NB110-57434] - Immunohistochemical staining of paraffin-embedded human cervical carcinoma using anti-PRC1 (cat. #110-57434). Rabbit IgG EP1513Y Hu, Ms, Rt F, ICC/IF, IP, P, WB
0.1 ml / €490.00
  Novus Biologicals Inc.

PRC1 antibody

Immunohistochemistry-Paraffin: PRC1 Antibody [NBP1-88856] - Immunohistochemical staining of human testis shows strong nuclear positivity in cells of seminiferus ducts. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PRC1 (transcript variant 1)

PRC1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

PRC1

PRC1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PRC1

PRC1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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