PRDM10 antibody

Principal name

PRDM10 antibody

Alternative names for PRDM10 antibody

Tristanin, TRIS, KIAA1231, PFM7, PR domain zinc finger protein 10, PR domain-containing protein 10

SwissProt ID

A2BID7 (Danre), Q3UTQ7 (Mouse), Q9NQV6 (Human)

Gene ID

56980 (PRDM10)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Rt (Rat)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP)

Background of PRDM10 antibody

Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger gene RIZ 1 is a tumor suppressor gene and a FOUNDING member of the PR domain family. RIZ 1 inactivation is commonly found in many types of human cancers and occurs through loss of mRNA expression, frame shift mutation, chromosomal deletion, and missense mutation. RIZ 1 is also a tumor susceptibility gene in mice. The loss of RIZ 1 mRNA in human cancers was shown to associate with DNA methylation of its promoter CpG island. Methylation of the RIZ 1 promoter strongly correlated with lost or decreased RIZ 1 mRNA expression in breast, liver, colon, and lung cancer cell lines as well as in liver cancer tissues.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PRDM10 antibody

WB Suggested Anti-PRDM10 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

PRDM10 (N-term) antibody

Figure 1. Western analysis of extracts from 293 cells using PRDM10 antibody. Mouse IgG1 48AT1224.90.46 Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PRDM10 antibody

Western analysis of extracts from 293 cells using PRDM10 monoclonal antibody, clone 48AT1224.90.46 ( Cat # MAB1150 ) . Mouse IgG1 48AT1224.90.46 Purified Hu, Ms E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

PRDM10 antibody

PRDM10 Goat Hu E
0.1 mg / €390.00
  Abnova Taiwan Corp.

PRDM10 antibody

PRDM10 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

PRDM10 antibody

Immunohistochemistry-Paraffin: PRDM10 Antibody [NBP1-81427] - Immunohistochemical staining of human duodenum shows strong nuclear positivity in glandular cells while paneth cells displayed additional strong cytoplasmic positivity. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

PRDM10 overexpression lysate

PRDM10 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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