PRDM11 / PFM8 antibody

Principal name

PRDM11 / PFM8 antibody

Alternative names for PRDM11 / PFM8 antibody

PR domain-containing protein 11

SwissProt ID

Q9NQV5 (Human)

Gene ID

56981 (PRDM11)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Goat, Chicken, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of PRDM11 / PFM8 antibody

The newly discovered family of PR domain genes is involved in tumorigenesis. Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein interacting zinc finger gene RIZ1 is a tumor suppressor gene and a FOUNDING member of the PR domain family. RIZ1 inactivation is commonly found in many types of human cancers and occurs through loss of mRNA expression, frame shift mutation, chromosomal deletion, and missense mutation.

General readings

1. Yang,X.-h. and Huang,S., et al.
A family of novel PR-domain (PRDM) genes as candidate tumor suppressors
2. , Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., et al.
Complete sequencing and characterization of 21,243 full-length human cDNAs.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PRDM11 / PFM8 (C-term) antibody

TA302841 (2µg/ml) staining of A549 lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PRDM11 / PFM8 antibody

WB Suggested Anti-PRDM11 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Spleen Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

PRDM11 / PFM8 antibody

PRDM11 / PFM8 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

PRDM11 / PFM8 antibody

PRDM11 polyclonal antibody ( Cat # PAB6287 ) staining ( 2 µg/ml ) of A-549 lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

PRDM11 / PFM8 antibody

Human Spleen; WB Suggested Anti-PRDM11 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Spleen; PRDM11 antibody - middle region (ARP34598_P050) in Human Spleen cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

PRDM11 / PFM8 antibody

Western Blot: PRDM11 Antibody [NB100-1525] - NB100-1525 (2ug/ml) staining of A549 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

PRDM11 / PFM8 antibody

Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-PFM8 ) Chicken Aff - Purified Hu WB
50 µg / €520.00
  Novus Biologicals Inc.

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