PRDM16 antibody

Principal name

PRDM16 antibody

Alternative names for PRDM16 antibody

KIAA1675, MEL1, PFM13, PR domain zinc finger protein 16, PR domain-containing protein 16, Transcription factor MEL1, MDS1/EVI1-like gene 1

SwissProt ID

Q9HAZ2 (Human)

Gene ID

63976 (PRDM16)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of PRDM16 antibody

PRDM16 is a zinc finger transcription factor and contains an N-terminal PR domain. The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Recent studies have shown that PRDM16 normally acts as a Smad3 binding protein that may be important for the development of orofacial structures through modulation of the TGF-beta signaling pathway. Other experiments have indicated that PRDM16 controls a bidirectional cell fate switch between skeletal myoblasts and brown fat cells.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PRDM16 (C-term) antibody

Formalin-Fixed, Paraffin-Embedded Human Skin stained with PRDM16 Antibody Cat.-No AP23499PU-N at 5 µg/ml after heat-induced antigen retrieval. Rabbit Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PRDM16 (C-term) antibody

Western blot analysis of PRDM16 in rat brain tissue lysate with PRDM16 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PRDM16 antibody

WB Suggested Anti-PRDM16 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

PRDM16 Control Peptide

PRDM16
50 µg / €160.00
  Acris Antibodies GmbH

PRDM16 antibody

PRDM16 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

PRDM16 antibody

PRDM16 Goat Hu E
0.1 mg / €390.00
  Abnova Taiwan Corp.

PRDM16 (Center) antibody

Human HepG2; WB Suggested Anti-PRDM16 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: HepG2 cell lysate; PRDM16 antibody - middle region (ARP33260_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PRDM16 (transcript variant 1)

PRDM16 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PRDM16 overexpression lysate

PRDM16 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PRDM16 (mGFP-tagged) - Human PR domain containing 16 (PRDM16), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PRDM16 (mGFP-tagged) - Human PR domain containing 16 (PRDM16), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, PRDM16 (Myc-DDK tagged) - Human PR domain containing 16 (PRDM16), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, PRDM16 (Myc-DDK tagged) - Human PR domain containing 16 (PRDM16), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

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