PRDM16 antibody

Principal name

PRDM16 antibody

Alternative names for PRDM16 antibody

KIAA1675, MEL1, PFM13, PR domain zinc finger protein 16, PR domain-containing protein 16, Transcription factor MEL1, MDS1/EVI1-like gene 1

SwissProt ID

Q9HAZ2 (Human)

Gene ID

63976 (PRDM16)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of PRDM16 antibody

Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger gene RIZ 1 is a tumor suppressor gene and a FOUNDING member of the PR domain family. RIZ 1 inactivation is commonly found in many types of human cancers and occurs through loss of mRNA expression, frame shift mutation, chromosomal deletion, and missense mutation. RIZ 1 is also a tumor susceptibility gene in mice. The loss of RIZ 1 mRNA in human cancers was shown to associate with DNA methylation of its promoter CpG island. Methylation of the RIZ 1 promoter strongly correlated with lost or decreased RIZ 1 mRNA expression in breast, liver, colon, and lung cancer cell lines as well as in liver cancer tissues.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PRDM16 (C-term) antibody

Formalin-Fixed, Paraffin-Embedded Human Skin stained with PRDM16 Antibody Cat.-No AP23499PU-N at 5 µg/ml after heat-induced antigen retrieval. Rabbit Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PRDM16 (C-term) antibody

Western blot analysis of PRDM16 in rat brain tissue lysate with PRDM16 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PRDM16 antibody

WB Suggested Anti-PRDM16 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

PRDM16 Control Peptide

PRDM16
50 µg / €160.00
  Acris Antibodies GmbH

PRDM16 antibody

PRDM16 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

PRDM16 antibody

PRDM16 Goat Hu E
0.1 mg / €390.00
  Abnova Taiwan Corp.

PRDM16 (Center) antibody

Human HepG2; WB Suggested Anti-PRDM16 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: HepG2 cell lysate; PRDM16 antibody - middle region (ARP33260_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

PRDM16 antibody

PRDM16 Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €480.00
  Novus Biologicals Inc.

PRDM16 antibody

Immunohistochemistry-Paraffin: PRDM16 Antibody [NBP1-77096] - Rat brain tissue with PRDM16 antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PRDM16 (transcript variant 1)

PRDM16 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PRDM16 overexpression lysate

PRDM16 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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