PRDM2 antibody

Principal name

PRDM2 antibody

Alternative names for PRDM2 antibody

PR domain zinc finger protein 2, KMT8, RIZ1, RIZ2, MTB-ZF, HUMHOXY1, Retinoblastoma protein-interacting zinc finger protein, MTE-binding protein, GATA-3-binding protein G3B, Lysine N-methyltransferase 8

SwissProt ID

Q13029 (Human), Q63755 (Rat)

Gene ID

7799 (PRDM2), 313678 (Prdm2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), ChIP assay (ChIP), Paraffin Sections (P)

Background of PRDM2 antibody

Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger gene RIZ 1 is a tumor suppressor gene and a founding member of the PR domain family. RIZ 1 inactivation is commonly found in many types of human cancers and occurs through loss of mRNA expression, frame shift mutation, chromosomal deletion, and missense mutation. RIZ 1 is also a tumor susceptibility gene in mice. The loss of RIZ 1 mRNA in human cancers was shown to associate with DNA methylation of its promoter CpG island. Methylation of the RIZ 1 promoter strongly correlated with lost or decreased RIZ 1 mRNA expression in breast, liver, colon, and lung cancer cell lines as well as in liver cancer tissues.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PRDM2 (1-347) antibody

Figure 1. Western blot analysis of anti-PRDM2 Mab (Cat. #AM11041P) in lysate from transformed cells. Lane A: mock plasmid, Lane B: PRDM2[1-347]-encoding plasmid. PRDM2[1-347] (arrow) was detected using purified Mab. Secondary HRP-anti-mouse was used for signal visualization with chemiluminescence. Mouse IgG1 33AT1045 Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PRDM2 antibody

Immunohistochemical analysis of RIZ1 in adenovirus-transduced tumor cells. Established HCT116 xenograft tumors at day 2 after infection of AdRIZ1, Adnull, or buffer alone were processed for RIZ1 in situ detection (TUNEL) analysis. Rabbit Ig Purified Hu, Ms, Rt IP, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PRDM2 antibody

PRDM2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

PRDM2 antibody

Western blot analysis of PRDM2 monoclonal antibody, clone 33AT1045 ( Cat # MAB1151 ) in lysate from transformed cells. Lane A : mock plasmid, Lane B : PRDM2 [1-347]-encoding plasmid. PRDM2 [1-347] ( arrow ) was detected using purified monoclonal antibody. Secondary HRP-anti-mouse was used for signal visualization with chemiluminescence. Mouse IgG1 33AT1045 Purified Hu, Ms ChIP, E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

PRDM2 antibody

Immunocytochemical analysis of Prdm2 in adenovirus-transduced tumor cells. Established HCT116 xenograft tumors at day 2 after infection of AdRIZ1, Adnull, or buffer alone were processed for RIZ1 in situ detection ( TUNEL ) analysis. Rabbit Purified Hu, Ms, Rt E, ICC/IF, IP, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

PRDM2 antibody

Immunohistochemistry-Paraffin: RIZ1 Antibody [NBP1-89644] - Immunohistochemical staining of human hippocampus shows strong nuclear positivity in neuronal cells. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PRDM2 (transcript variant 4)

PRDM2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PRDM2

PRDM2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PRDM2

PRDM2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PRDM2 overexpression lysate

PRDM2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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