PREX1 antibody

Principal name

PREX1 antibody

Alternative names for PREX1 antibody

P-Rex1, KIAA1415, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, PtdIns(3,4,5)-dependent Rac exchanger 1

SwissProt ID

Q69ZK0 (Mouse), Q8TCU6 (Human), Q9P2D2 (Human)

Gene ID

57580 (PREX1)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PREX1 antibody

The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.

General readings

1. Qin J, Xie Y, Wang B, Hoshino M, Wolff DW, Zhao J, Scofield MA, Dowd FJ, Lin MF, Tu Y.
Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis.Oncogene 2009 Apr 28 (16): 1853-63.
PMID: 19305425

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PREX1 antibody

(1ug/ml) staining of Human Temporal Cortex lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PREX1 (1514-1526) antibody

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Hst, Hu, L, Mky, Ms, Op, Prim, Rt, Tr E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PREX1 (Center) antibody

Western blot analysis of PREX1 Antibody (Center) (Cat. #AP53440PU-N) in MCF-7 cell line lysates (35µg/lane). PREX1 (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PREX1 (C-term) antibody

PREX1 Antibody (C-term) (Cat. #AP53441PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PREX1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu, P WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PREX1 antibody

PREX1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

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