PRKAA2 antibody

Principal name

PRKAA2 antibody

Alternative names for PRKAA2 antibody

AMPK2, AMPK alpha-2 chain, 5'-AMP-activated protein kinase catalytic subunit alpha-2

SwissProt ID

P54646 (Human), Q09137 (Rat), Q28948 (Pig), Q8BRK8 (Mouse)

Gene ID

5563 (PRKAA2), 78975 (Prkaa2)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Por (Porcine), Rt (Rat), Eq (Equine), Rb (Rabbit), Sh (Sheep), Ze (Zebrafish)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of PRKAA2 antibody

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kise (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and ictivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008].

General readings

1. Dong Y, Zhang M, Liang B, Xie Z, Zhao Z, Asfa S, Choi HC, Zou MH, Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo. Circulation 2010 Feb 121 (6): 792-803.
PMID: 20124121

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PRKAA2 antibody

  Rabbit Polyclonal antibody to AMPK alpha 2 (protein kinase, AMP-activated, alpha 2 catalytic subunit)  
Sample (30 ug of whole cell lysate). . A:NIH-3T3. 7.5% SDS PAGE. . TA308756 diluted at 1:1000. Rabbit IgG Aff - Purified Hu, Ms ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PRKAA2 antibody

  Rabbit anti-PRKAA2 (AMPK1/AMPK2, Phospho-Ser485/Ser491) polyclonal antibody(Phospho-specific)  
Western blot analysis of extracts from HeLa cells untreated or treated with heat shock (30min), using AMPK1/AMPK2 (phospho-Ser485/Ser491) antibody. Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PRKAA2 antibody

  Goat Anti-PRKAA2 Antibody  
(1ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PRKAA2 antibody

  Anti-PRKAA2 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human liver and thyroid cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human liver cancer tissue using PRKAA2 antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

PRKAA2 antibody

  Anti-PRKAA2 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human liver and lung cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human liver cancer tissue using PRKAA2 antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

PRKAA2 antibody

  Rabbit Polyclonal Anti-PRKAA2 Antibody - middle region  
WB Suggested Anti-PRKAA2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Por, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PRKAA2 (C-term) antibody

Western blot analysis of anti-AMPK alpha2 C-term Pab (AP13880PU-N) in mouse heart tissue lysate. AMPK alpha2 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PRKAA2 (C-term) antibody

Formalin-fixed and paraffin-embedded human skeletal muscle reacted with PRKAA2 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PRKAA2 (Center)/(Thr172) antibody

PRKAA2 (Thr172) antibody (Center) (Cat. #AP53442PU-N) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the PRKAA2 (Thr172) antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

PRKAA2 overexpression lysate

PRKAA2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Prkaa2 (GFP-tagged ORF) - Rat protein kinase, AMP-activated, alpha 2 catalytic subunit (Prkaa2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Prkaa2 (GFP-tagged ORF) - Rat protein kinase, AMP-activated, alpha 2 catalytic subunit (Prkaa2), 200 uL, >10^7 TU/mL  
200 µl / €1,190.00
  OriGene Technologies, Inc.

Lenti ORF particles, Prkaa2 (Myc-DDK-tagged ORF) - Rat protein kinase, AMP-activated, alpha 2 catalytic subunit (Prkaa2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Prkaa2 (Myc-DDK-tagged ORF) - Rat protein kinase, AMP-activated, alpha 2 catalytic subunit (Prkaa2), 200 uL, >10^7 TU/mL  
200 µl / €1,064.00
  OriGene Technologies, Inc.

12 Item(s)

per page
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