PRKAR2A antibody

Principal name

PRKAR2A antibody

Alternative names for PRKAR2A antibody

PRKAR2, PKR2, protein kinase A RII-alpha, PKA RII, PKA R2, cAMP-dependent protein kinase type II-alpha regulatory subunit

SwissProt ID

O49196 (Arath), P00515 (Bovin), P05207 (Pig), P12367 (Mouse), P12368 (Rat), P13861 (Human)

Gene ID

100139910 (PRKAR2A), 5576, 29699 (Prkar2a)

Available reactivities

Bov (Bovine), Hu (Human), Por (Porcine), Ms (Mouse), Can (Canine), Mky (Monkey), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Functional assay (FN), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Flow Cytometry (F)

Background of PRKAR2A antibody

The second messenger cyclic AMP (cAMP) mediates diverse cellular responses to external signals such as proliferation, ion transport, regulation of metabolism and gene transcription by activation of the cAMP-dependent protein kinase (cAPK or PKA). Activation of PKA occurs when cAMP binds to the two regulatory subunits of the tetrameric PKA holoenzyme resulting in release of active catalytic subunits. Three catalytic (C) subunits have been identified, designated Cα, Cβ and Cγ, that each represent specific gene products. Cα and Cβ are closely related (93% amino acid sequence similarity), where as Cγ displays 83% and 79% similarity to Cα and Cβ, respectively. Activation of transcription upon elevation of cAMP levels results from translocation of PKA to the nucleus where it phosphorylates the transcription factor cAMP response element binding protein (CREB) on serine 133 which in turn leads to TFIIB binding to TATA-box-binding protein TBP1, thus linking phospho-CREB to the pol II transcription initiation complex.

General readings

Yang H., et al. (2013) J. Biol. Chem. 288 (12), 8737-8749

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PRKAR2A antibody

Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-PRKAR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501195, Dilution 1:50) Mouse IgG1 OTI5F1 Purified Can, Hu, Mky, Rt F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

PRKAR2A antibody

Immunohistochemical staining of paraffin-embedded prostate tissue within the normal limits using anti-PRKAR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501104, Dilution 1:50) Mouse IgG1 OTI1G7 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PRKAR2A antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of prostate tissue using anti-PRKAR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501106, Dilution 1:50) Mouse IgG1 OTI1C4 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PRKAR2A antibody

Immunohistochemical staining of paraffin-embedded pancreas tissue within the normal limits using anti-PRKAR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501129, Dilution 1:50) Mouse IgG1 OTI1A7 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PRKAR2A antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-PRKAR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501143, Dilution 1:50) Mouse IgG1 OTI1B4 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PRKAR2A antibody

Immunohistochemical staining of paraffin-embedded Kidney tissue within the normal limits using anti-PRKAR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501144, Dilution 1:50) Mouse IgG1 OTI4A3 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PRKAR2A antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-PRKAR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501145, Dilution 1:50) Mouse IgG1 OTI4H8 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PRKAR2A antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-PRKAR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501146) Mouse IgG1 OTI1F8 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PRKAR2A antibody

Immunoperoxidase of monoclonal antibody to PRKAR2A on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml] Mouse IgG1 6A9 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PRKAR2A antibody

Western blot (WB) analysis of PKA IIα reg antibody (Cat.-No.: AP06667PU-N) in extracts from 293 cells. Rabbit Aff - Purified Hu ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PRKAR2A antibody

PRKAR2A Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

PRKAR2A antibody

PRKAR2A MaxPab polyclonal antibody. Western Blot analysis of PRKAR2A expression in human colon. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

PRKAR2A antibody

PRKAR2A Mouse IgG1 3C7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PRKAR2A antibody

Western blot analysis of PRKAR2A polyclonal antibody ( Cat # PAB4582 ) in mouse brain tissue lysate . PRKAR2A ( arrow ) was detected using purified PRKAR2A polyclonal antibody ( Cat # PAB4582 ) . Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence . Rabbit Hu, Ms E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

PRKAR2A antibody

Western blot analysis of extracts from 293/HepG2 cells, using KAP2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

PRKAR2A antibody

Western blot analysis of extracts from 293/HepG2 cells, using KAP2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

PRKAR2A (Center) antibody

Human Fetal Kidney; WB Suggested Anti-PRKAR2A Antibody. . Titration: 1.0 ug/ml. . Positive Control: Fetal Kidney; PRKAR2A antibody - middle region (ARP61563_P050) in Human Fetal Kidney cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

PRKAR2A antibody

PRKAR2A Mouse IgG1 RS-6 Purified Bov, Hu, Por E, FN, ICC/IF
1 mg / €310.00
  HyTest Ltd.

PRKAR2A antibody

PRKAR2A Mouse IgG2a RS-17 Purified Bov, Hu, Por E, ICC/IF
1 mg / €310.00
  HyTest Ltd.

PRKAR2A antibody

PRKAR2A Mouse IgG2a RS-30 Purified Bov, Hu, Por E, FN, ICC/IF
1 mg / €310.00
  HyTest Ltd.

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