PRKAR2B antibody

Principal name

PRKAR2B antibody

Alternative names for PRKAR2B antibody

PRKAR2, cAMP-dependent protein kinase type II-beta regulatory subunit

SwissProt ID

P12369 (Rat), P31322 (Bovin), P31323 (Human), P31324 (Mouse)

Gene ID

5577 (PRKAR2B), 282463, 19088 (Prkar2b), 24679

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of PRKAR2B antibody

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity. The studies also suggest that this subunit may mediate the gene induction and cataleptic behavior induced by haloperidol. [provided by RefSeq].

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PRKAR2B antibody

  Rabbit polyclonal PKA-R2beta (Ab-113) antibody  
Western blot analysis of extracts from HepG2 cells and K562 cells, using PKA-R2ß (Ab-113) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PRKAR2B antibody

  Rabbit polyclonal PKA-R2beta (Ser113) antibody(Phospho-specific)  
PRKAR2B Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PRKAR2B antibody

Immunohistochemistry (IHC) analyzes of PKA IIβ reg antibody (Cat.-No.: AP01453PU-N) in paraffin-embedded human cervix carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PRKAR2B (N-term) antibody

Western blot analysis of anti-PRKAR2B Pab in mouse brain tissue lysate. PRKAR2B (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PRKAR2B (Center) antibody

Western blot analysis of PRKAR2B (arrow) using rabbit polyclonal PRKAR2B Antibody (Center) (Cat. #AP53444PU-N). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PRKAR2B gene. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PRKAR2B pSer113 antibody

Western blot analysis of extracts from COS-7 cells treated with PMA using PKA-R2β (Phospho-Ser113) Antibody AP55723PU-N.The lane on the right is treated with the antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €340.00
  Acris Antibodies GmbH

PRKAR2B pSer113 antibody

Western blot analysis of extracts from COS-7 cells treated with PMA using PKA-R2β (Phospho-Ser113) Antibody AP55723PU-N.The lane on the right is treated with the antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µl / €270.00
  Acris Antibodies GmbH

PRKAR2B pSer113 antibody

Western blot analysis of extracts from COS7 cells treated with PMA 125ng/ml 30', using PKA-R2 beta (Phospho-Ser113) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

PRKAR2B pSer113 antibody

Western blot analysis of extracts from COS7 cells treated with PMA 125ng/ml 30', using PKA-R2 beta (Phospho-Ser113) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

PRKAR2B antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using PKA-R2 beta (Ab-113) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

PRKAR2B antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using PKA-R2 beta (Ab-113) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

PRKAR2B - human gene knockout kit via CRISPR

PRKAR2B - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PRKAR2B - human gene knockout kit via CRISPR

PRKAR2B - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PRKAR2B - human gene knockout kit via CRISPR

PRKAR2B - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PRKAR2B - human gene knockout kit via CRISPR

PRKAR2B - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Prkar2b - mouse gene knockout kit via CRISPR

Prkar2b - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PRKAR2B

  Recombinant protein of human protein kinase, cAMP-dependent, regulatory, type II, beta (PRKAR2B)  
PRKAR2B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PRKAR2B (mGFP-tagged) - Human protein kinase, cAMP-dependent, regulatory, type II, beta (PRKAR2B), 200 uL, >10^7 TU/mL

Lenti ORF particles, PRKAR2B (mGFP-tagged) - Human protein kinase, cAMP-dependent, regulatory, type II, beta (PRKAR2B), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, PRKAR2B (Myc-DDK tagged) - Human protein kinase, cAMP-dependent, regulatory, type II, beta (PRKAR2B) , 200 uL, >10^7 TU/mL

Lenti ORF particles, PRKAR2B (Myc-DDK tagged) - Human protein kinase, cAMP-dependent, regulatory, type II, beta (PRKAR2B) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Prkar2b (GFP-tagged) - Mouse protein kinase, cAMP dependent regulatory, type II beta (Prkar2b), 200 uL, >10^7 TU/mL

Lenti ORF particles, Prkar2b (GFP-tagged) - Mouse protein kinase, cAMP dependent regulatory, type II beta (Prkar2b), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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