PRKCZ antibody

Principal name

PRKCZ antibody

Alternative names for PRKCZ antibody

nPKC-zeta, PKC-zeta, PKC zeta, PKC2, Protein kinase C zeta type

SwissProt ID

O19111 (Rabit), P09217 (Rat), Q02956 (Mouse), Q05513 (Human)

Gene ID

25522 (Prkcz), 5590 (PRKCZ)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Rb (Rabbit), Mky (Monkey), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), EPair for Elisa (EPair), ELISA (detection) (E(detection)), Frozen Sections (C), Flow Cytometry (F)

Background of PRKCZ antibody

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC.Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.

General readings

Xie,Z., (2006) J. Biol. Chem. 281 (10), 6366-6375

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PRKCZ antibody

Western blot analysis of PKC zeta expression in PMA treated COS7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PRKCZ antibody

Western blot analysis of extracts of HeLa cell line, using PKCz antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

PRKCZ antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PRKCZ (RC202472, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PRKCZ. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PRKCZ antibody

Western blot of PKC-Z Anti-PKC-Z (DB 011): Lane 1: 50ng of recombinant Human PKC-Z (N-term GST PKC-Z; BML-SE443-0005), Lane 2: Mouse brain crude protein lysate
(100 μg), Lane 3: Rat brain crude protein lysate (100 μg) Rabbit R14-K Aff - Purified Hu, Ms, Rt E, IP, WB
0.1 ml / €420.00
  DB Biotech, spol. s r.o.

Sample sizes available

PRKCZ antibody

Western blot of PKC-Z Anti-PKC-Z (DB 011): Lane 1: 50ng of recombinant Human PKC-Z (N-term GST PKC-Z; BML-SE443-0005), Lane 2: Mouse brain crude protein lysate
(100 μg), Lane 3: Rat brain crude protein lysate (100 μg) Rabbit R14-K Aff - Purified Hu, Ms, Rt E, IP, WB
50 µl / €280.00
  DB Biotech, spol. s r.o.

Sample sizes available

PRKCZ antibody

PRKCZ Rabbit IgG S19-V FITC Hu F
100 Tests / €540.00
  DB Biotech, spol. s r.o.

Sample sizes available

PRKCZ pThr410 antibody

Immunohistochemistry (IHC) analysis of PKCZ pThr410 antibody (Cat.-No.: AP01667PU-N) in paraffin-embedded human lungcarcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PRKCZ antibody

Immunohistochemistry (IHC) analyzes of PKC ζ antibody (Cat.-No.: AP06286PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PRKCZ antibody

Immunohistochemistry (IHC) analyzes of PKC ζ  antibody (Cat.-No.: AP06565PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PRKCZ (N-term) antibody

Brain, cerebellum: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Mky, Ms, Prim, Rb, Rt E, P
50 µg / €470.00
  Acris Antibodies GmbH

PRKCZ (1st Cytopl. Dom.) antibody

Testis, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Bear, Can, Elephant, Eq, Hu, Mky, Prim, Rt E, P
50 µg / €470.00
  Acris Antibodies GmbH

PRKCZ pThr560 antibody

Western blot analysis of extracts from COS7 cells treated with PMA using Phospho-PKC zeta (Thr560) antibody AP55910PU-N.The lane on the right is treated with the antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €340.00
  Acris Antibodies GmbH

PRKCZ pThr560 antibody

Western blot analysis of extracts from COS7 cells treated with PMA using Phospho-PKC zeta (Thr560) antibody AP55910PU-N.The lane on the right is treated with the antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µl / €270.00
  Acris Antibodies GmbH

PRKCZ antibody

Western Blot analysis of PRKCZ expression in transfected 293T cell line (H00005590-T01) by PRKCZ MaxPab polyclonal antibody.

Lane 1: PRKCZ transfected lysate(65.12 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

PRKCZ antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between PRKCZ and AKT3. HeLa cells were stained with anti-PRKCZ rabbit purified polyclonal 1:1200 and anti-AKT3 mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PRKCZ antibody

Detection limit for recombinant GST tagged PRKCZ is approximately 0.1ng/ml as a capture antibody. Mouse IgG2b 2D1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PRKCZ antibody

Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using PRKCZ polyclonal antibody ( Cat # PAB5521 ) . Rabbit Hu, Ms, Rt P
0.1 mg / €390.00
  Abnova Taiwan Corp.

PRKCZ antibody

PRKCZ polyclonal antibody ( Cat # PAB10165 ) staining of formallin fixed paraffin embedded human brain (cerebellum) tissue at a dilution of 3 µg/ml. Antigen retrieval using a citrate bufferand steam/heat was utilized. Hu
50 µg / €640.00
  Abnova Taiwan Corp.

PRKCZ (579-592) antibody

PRKCZ Rabbit Rt C, E, ICC/IF, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

PRKCZ pThr410 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using PKC zeta (Phospho-Thr410) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

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