PRKD2 / PKD2 antibody

Principal name

PRKD2 / PKD2 antibody

Alternative names for PRKD2 / PKD2 antibody

PKC-D2, nPKC-D2, HSPC187, Serine/threonine-protein kinase D2

SwissProt ID

Q5XIS9 (Rat), Q8BZ03 (Mouse), Q9BZL6 (Human)

Gene ID

25865 (PRKD2), 101540 (Prkd2), 292658

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Mky (Monkey)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PRKD2 / PKD2 antibody

PKD2, a member of the polycystin family, functions as a calcium permeable cation channel. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. PKD2 interacts with PKD1, potentially through the C-terminal region. PKD1 requires the presence of PKD2 for stable expression. PKD2 also interacts with CD2AP. This protein is strongly expressed in ovary, fetal and adult kidney, testis, and small intestine, but is not detected in peripheral leukocytes. Defects in PKD2 are the cause of autosomal dominant polycystic kidney disease type II (ADPKD-2) which represent approximately 15% of cases of autosomal dominant polycystic kidney disease, a common autosomal dominant genetic disease affecting about 1 out 1000 individuals. ADPKD is characterized by progressive formation and enlargement of cysts in both kidneys, typically leading to end-stage renal disease in adult life. Cysts also occurs in the liver and other organs. All mutations, scattered between exons 1 and 11, result in a truncated PKD2 that lacks both the calcium-binding EF-hand domain and the two cytoplasmic domains required for the interaction of PKD2 with PKD1 and with itself. ADPKD type II is clinically milder than ADPKD type I, but it has a deleterious impact on overall life expectancy.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PRKD2 / PKD2 antibody

  Rabbit Polyclonal antibody to PKD2 (protein kinase D2)  
Sample (30 ug of whole cell lysate). A: Molt-4 . 7.5% SDS PAGE. TA308724 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PRKD2 / PKD2 antibody

  anti-PRKD2 (Protein Kinase D2) mouse monoclonal antibody, clone OTI3F7 (formerly 3F7)  
Anti-PRKD2 mouse monoclonal antibody (TA501647) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PRKD2(RC215335). Mouse IgG1 OTI3F7 Purified Can, Hu, Mky, Rt F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PRKD2 / PKD2 antibody

  PRKD2 (Protein Kinase D2) mouse monoclonal antibody, clone OTI5A3 (formerly 5A3)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-PRKD2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501648) Mouse IgG2b OTI5A3 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PRKD2 / PKD2 antibody

  anti-PRKD2 (Protein Kinase D2) mouse monoclonal antibody, clone OTI5G1 (formerly 5G1)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-PRKD2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501672, Dilution 1:50) Mouse IgG2b OTI5G1 Purified Can, Hu, Mky, Rt F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PRKD2 / PKD2 antibody

  anti-PRKD2 (Protein Kinase D2) mouse monoclonal antibody, clone OTI4F1 (formerly 4F1)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-PRKD2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501684, Dilution 1:50) Mouse IgG2a OTI4F1 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PRKD2 / PKD2 antibody

  PRKD2 (Protein Kinase D2) mouse monoclonal antibody, clone OTI3B12 (formerly 3B12)  
Anti-PRKD2 mouse monoclonal antibody (TA501775) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PRKD2(RC215335). Mouse IgG1 OTI3B12 Purified Can, Hu, Mky, Rt F, ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

PRKD2 / PKD2 (C-term) antibody

Human Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PRKD2 / PKD2 antibody

  Rabbit polyclonal PKD2 (Ab-876) antibody  
Western blot analysis of extracts from NIH/3T3 cells, treated with PMA (250ng/ml, 15mins), using PKD2 (Ab-876) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PRKD2 / PKD2 antibody

  Rabbit Polyclonal Anti-PRKD2 Antibody (Internal)  
PRKD2 / PKD2 Rabbit Purified Hu
50 µg / €400.00
  OriGene Technologies, Inc.

PRKD2 / PKD2 antibody

  anti-PRKD2 (Protein Kinase D2) mouse monoclonal antibody, clone OTI2E2 (formerly 2E2)  
Anti-PRKD2 mouse monoclonal antibody (TA501625) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PRKD2(RC215335). Mouse IgG2a OTI2E2 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PRKD2 / PKD2 antibody

  PRKD2 (Protein Kinase D2) mouse monoclonal antibody, clone OTI3A1 (formerly 3A1)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PRKD2 (RC215335, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PRKD2. Mouse IgG2b OTI3A1 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PRKD2 / PKD2 antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2b 2E4 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

PRKD2 / PKD2 antibody

Western blot analysis of PKD2 Antibody (Cat.-No AP06570PU-N) in extracts from NIH/3T3 cells treated with PMA 250ng/ml 15'. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PRKD2 / PKD2 (C-term) antibody

AP14814PU-N PKD2 antibody staining of Formalin-Fixed, Paraffin-Embedded Human cancer tissue. This primary antibody was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PRKD2 / PKD2 pSer876 antibody

Western blot analysis of extracts from NIH-3T3 cells treated with PMA 250ng/ml 15', using PKD2 (Phospho-Ser876) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

PRKD2 / PKD2 pSer876 antibody

Western blot analysis of extracts from NIH-3T3 cells treated with PMA 250ng/ml 15', using PKD2 (Phospho-Ser876) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

PRKD2 / PKD2 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PKD2 (Ab-876) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

PRKD2 / PKD2 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PKD2 (Ab-876) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

PRKD2 - human gene knockout kit via CRISPR

PRKD2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PRKD2 - human gene knockout kit via CRISPR

PRKD2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Items 1 to 20 of 39 total

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