PRMT6 / HRMT1L6 antibody

Principal name

PRMT6 / HRMT1L6 antibody

Alternative names for PRMT6 / HRMT1L6 antibody

Protein arginine N-methyltransferase 6, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6, Histone-arginine N-methyltransferase PRMT6

SwissProt ID

Q5E9L5 (Bovin), Q6NZB1 (Mouse), Q96LA8 (Human)

Gene ID

55170 (PRMT6)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat), Mky (Monkey), Por (Porcine), Eq (Equine), GP (Guinea Pig)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of PRMT6 / HRMT1L6 antibody

Arginine methyltransferase that can catalyze the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA), with a strong preference for the formation of aDMA. Preferentially methylates arginyl residues present in a glycine and arginine-rich domain and displays preference for monomethylated substrates. Specifically mediates the asymmetric dimethylation of histone H3 'Arg-2' to form H3R2me2a. H3R2me2a represents a specific tag for epigenetic transcriptional repression and is mutually exclusive with methylation on histone H3 'Lys-4' (H3K4me2 and H3K4me3). Acts as a transcriptional repressor of various genes such as HOXA2, THBS1 and TP53. Repression of TP53 blocks cellular senescence (By similarity). Also methylates histone H2A and H4 'Arg-3' (H2AR3me and H4R3me, respectively). Acts as a regulator of DNA base excision during DNA repair by mediating the methylation of DNA polymerase beta (POLB), leading to the stimulation of its polymerase activity by enhancing DNA binding and processivity. Methylates HMGA1. Regulates alternative splicing events. Acts as a transcriptional coactivator of a number of steroid hormone receptors including ESR1, ESR2, PGR and NR3C1. Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator. May play a role in innate immunity against HIV-1 in case of infection by methylating and impairing the function of various HIV-1 proteins such as Tat, Rev and Nucleocapsid protein p7 (NC).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PRMT6 / HRMT1L6 antibody

(0.5ug/ml) staining of MCF7 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Por, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PRMT6 / HRMT1L6 antibody

Western blot analysis of PRMT6 using Jurkat cell lysate (Lane1 & 2). Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PRMT6 / HRMT1L6 antibody

Western Blot: PRMT6 Antibody [TA336434] - Analysis of PRMT6 in HeLa lysate using PRMT6 antibody at 1:500 dilution. Rabbit Purified Hu, Ms WB
0.2 ml / €325.00
  OriGene Technologies, Inc.

PRMT6 / HRMT1L6 antibody

WB Suggested Anti-PRMT6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: 293T cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

PRMT6 / HRMT1L6 antibody

Western blot detection of PRMT6 in Hel and 293T cell lysates using PRMT6 mouse mAb (1:1000 diluted).Predicted band size: 42KDa.Observed band size: 42KDa. Mouse IgG1 2C3-F1-G1 Purified ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PRMT6 / HRMT1L6 antibody

Western blot analysis using PRMT6 mouse mAb against A431 (1), Hela (2), A549 (3) and HEK293 (4) cell lysate. Mouse IgG1 4G2 Ascites Hu, Mky E, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

PRMT6 / HRMT1L6 (23-43) antibody

Formalin-Fixed, Paraffin-Embedded Human Breast tissue stained with PRMT6 Antibody Cat.-No AP07178PU-N at 1/100 dilution after heat-induced antigen retrieval. Rabbit IgG Purified Elephant, Eq, Hu, Mky, Ms, Prim ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

PRMT6 / HRMT1L6 (N-term) antibody

Figure 2. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PRMT6 / HRMT1L6 antibody

PRMT6 / HRMT1L6 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

PRMT6 / HRMT1L6 antibody

PRMT6 / HRMT1L6 Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

PRMT6 / HRMT1L6 antibody

PRMT6 / HRMT1L6 Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

PRMT6 / HRMT1L6 antibody

PRMT6 / HRMT1L6 Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PRMT6 / HRMT1L6 antibody

PRMT6 / HRMT1L6 Mouse IgG2a 3C3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PRMT6 / HRMT1L6 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

PRMT6 / HRMT1L6 antibody

Human 293T; WB Suggested Anti-PRMT6 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: 293T cell lysate; PRMT6 antibody - middle region (ARP40190_P050) in Human 293T cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

PRMT6 / HRMT1L6 antibody

Western Blot: PRMT6 Antibody [NB110-40712] - Detection of Human PRMT6 Immunoprecipitates.  Whole cell lysate (1 mg for IP,  20% of IP loaded) from HeLa cells.  Antibodies: anti-PRMT6 antibody NB110-40712 used for IP at 3 ug/mg  lysate. Rabbit Aff - Purified Hu IP
0.1 mg / €440.00
  Novus Biologicals Inc.

PRMT6 / HRMT1L6 antibody

Immunohistochemistry-Paraffin: PRMT6 Antibody [NB110-40713] - See Notes, IHC Caption A Rabbit Aff - Purified Hu P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

PRMT6 / HRMT1L6 antibody

Immunohistochemistry: PRMT6 Antibody [NBP1-41112]-FFPE section of human colon carcinoma. Affinity purified rabbit anti-PRMT6 used_x000d_
at a dilution of 1:250. Rabbit Hu, Ms P
0.1 ml / €500.00
  Novus Biologicals Inc.

PRMT6 / HRMT1L6 antibody

Western Blot: PRMT6 Antibody (4G2) [NBP1-51597] - Western blot analysis using PRMT6 mouse mAb against A431 (1), Hela (2), A549 (3) and HEK293 (4) cell lysate. Mouse IgG1 4G2 Purified Hu, Mky E, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PRMT6 / HRMT1L6

PRMT6 / HRMT1L6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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