PROK1 antibody

Principal name

PROK1 antibody

Alternative names for PROK1 antibody

Prokineticin-1, Prokineticin 1, Mambakine, EG-VEGF, Endocrine-gland-derived vascular endothelial growth factor

SwissProt ID

P58294 (Human), Q8R414 (Rat)

Gene ID

84432 (PROK1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Flow Cytometry (F), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of PROK1 antibody

Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) induces proliferation, migration, and fenestration in capillary endothelial cells derived from endocrine glands. EG-VEGF possesses an HIF-1 binding site; its expression is induced by hypoxia and restricted to the steroidogenic glands (ovary, testis, adrenal and placenta). Expression of EG-VEGF is often complementary to the expression of VEGF, suggesting that these molecules function in a coordinated manner. EG-VEGF is an example of a class of highly specific mitogens that act to regulate proliferation and differentiation of the vascular endothelium in a tissue-specific manner. It is expressed primarily in one type of tissue and acts selectively on one type of endothelium. EG-VEGF, possibly through binding to a G protein-coupled receptor, results in the activation of MAPK p44/42 and phosphatidylinositol 3-kinase signaling pathways, leading to proliferation, migration and survival of responsive endothelial cells .

General readings

Brouillet S, Hoffmann P, Chauvet S, Salomon A, Chamboredon S, Sergent F, Benharouga M, Feige JJ, Alfaidy N. Revisiting the role of hCG: new regulation of the angiogenic factor EG-VEGF and its receptors. Cell Mol Life Sci. 2011 Dec 3.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PROK1 antibody

Western blot analysis using recombinant human EG-VEGF. Rabbit Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PROK1 antibody

To detect hEG-VEGF by direct ELISA (using 100 ul/well antibody solution) a concentration of 0.25-1.0 ug/ml of this antibody is required.  This biotinylated polyclonal antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2-0.4 ng/well of recombinant hEG-VEGF. Goat IgG Purified Hu E, WB
50 µg / €325.00
  OriGene Technologies, Inc.

PROK1 antibody

To detect hEG-VEGF by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.5 - 2.0 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Human EG-VEGF (TA328295) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hEG-VEGF. Goat IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PROK1 antibody

A: chondric villi at 9 weeks of gestation immunostained (brown staining) with anti-PK1/EG-VEGF antibody 0,33 µg/ml.
B: negativ control treated preimmune serum. All sections were vounterstained with heamatoxylin. Cytotrophoblast (Cyt), Hobfauer cells (Ho), Ectravillous trophoblast (EVT), Syncytiotrophoblast (St)
C: Sensitivity of PK1/EG-VEGF antibody tested by Western Blot on indicated quantities of recombinant human OK1/EG-VEGF.
The specificity was tested in the presence of 9,6 µg/ml antigenic peptide. Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

PROK1 antibody

PROK1 Goat Biotin Hu E, WB
25 µg / €230.00
  Acris Antibodies GmbH

PROK1 antibody

PROK1 Goat Biotin Hu E, WB
50 µg / €340.00
  Acris Antibodies GmbH

PROK1 antibody

PROK1 Goat Aff - Purified Hu E, WB
50 µg / €220.00
  Acris Antibodies GmbH

PROK1 antibody

PROK1 Goat Aff - Purified Hu E, WB
0.1 mg / €330.00
  Acris Antibodies GmbH

PROK1 antibody

Immunofluorescence of purified MaxPab antibody to PROK1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

PROK1 antibody

Western Blot analysis of PROK1 expression in transfected 293T cell line (H00084432-T02) by PROK1 MaxPab polyclonal antibody.

Lane 1: PROK1 transfected lysate(11.55 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

PROK1 antibody

Western Blot analysis of PROK1 expression in transfected 293T cell line (H00084432-T02) by PROK1 MaxPab polyclonal antibody.

Lane 1: PROK1 transfected lysate(11.55 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

PROK1 antibody

PROK1 Mouse IgG2b 3C3 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

PROK1 antibody

Western blot analysis of EG-VEGF expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

PROK1 antibody

Western blot analysis of EG-VEGF expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

PROK1 antibody

Western blot analysis of EG-VEGF expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

PROK1 antibody

Prokineticin 1 Antibody [NB100-2901] - : Polyclonal Antibody to Prokineticin 1 (PK1)/(EG-VEGF)  From rabbit.   IMMUNOGEN: Synthetic peptide derived from N terminal region of Human prokinectin 1. Also known as endocrine gland-derived VEGF (EG-VEGF). SPECIFICITY: Reacts with human prokinectin 1.   APPLICATION: FACS, IHC, WB.  (IHC: Chorionic villi at 9 weeks of gestation stained with PAb to Prokineticin 1 (human) (NT). Cytotrophoblast (Ct), Hobfauer cells (Ho), Extravillous trophoblast (EVT), Syncytiotrophoblast (St)).  Hoffmann.P, Feige.JJ, Alfaidy.N.Expression and oxygen regulation of endocrine gland-derived vascular endothelial growth factor/prokineticin-1 and its receptors in human placenta during early pregnancy.Endocrinology. 2006 Apr;147(4):1675-84. Rabbit Serum Hu, Ms E, F, P, WB
0.2 ml / €400.00
  Novus Biologicals Inc.

PROK1 antibody

Immunohistochemistry-Paraffin: Prokineticin 1 Antibody (MM0043-2L13) [NB110-93514] - Formalin fixed and paraffin embedded normal human placenta tissue is subjected to mouse anti human EG-VEGF. Mouse IgG2 MM0043-2L13 Purified Hu, Ms, Rt E, WB
0.1 mg / €450.00
  Novus Biologicals Inc.

PROK1 antibody

Immunohistochemistry-Paraffin: Prokineticin 1 Antibody [NBP1-84885] - Immunohistochemical staining of human rectum shows strong cytoplasmic and nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PROK1

PROK1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 20 µg / €199.00

Special Price: 20 µg / €139.00

  OriGene Technologies, Inc.

PROK1

PROK1 Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

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