Prolactin receptor antibody

Principal name

Prolactin receptor antibody

Alternative names for Prolactin receptor antibody

PRLR, PRL-R

SwissProt ID

O46561 (Sheep), P05710 (Rat), P14787 (Rabit), P16471 (Human), Q04594 (Chick), Q08501 (Mouse), Q28172 (Bovin), Q6JTA8 (Pig), Q9UHJ5 (Human)

Gene ID

5618 (PRLR), 24684 (Prlr), 19116

Available reactivities

Eq (Equine), Hu (Human), Por (Porcine), Rb (Rabbit), Rt (Rat), Ms (Mouse)

Available hosts

Mouse, Sheep, Rabbit

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Neutralisation (NEUT)

Background of Prolactin receptor antibody

Prolactin (PRL) is a hormone involved in a variety of important functions including ion transport and osmoregulation, stimulation of milk, protein synthesis as well as the regulation of numerous reproductive functions. PRL exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane PRL receptor. Immunoreactive PRL receptor, a member of the cytokine receptor family, varies in size (short and long forms) with tissue source and species, from ~40 kDa to 100 kDa.
The PRL receptor consists of at least three separate domains: an extracellular region with 5 cysteines which contains the prolactin binding site, a single transmembrane domain and a cytoplasmic region, the length of which appears to influence ligand binding and regulate cellular function.

General readings

Elberg G et al. Mitogenic and binding properties of monoclonal antibodies to the prolactin receptor in Nb2 rat lymphoma cells. Selective enhancement by anti-mouse IgG. J Biol Chem 265:14770-6 (1990). Endo., 124(5): 2499-2508, 1989.
Endo., 134(5): 2108-2114, 1994.
Endo., 135(4): 1299-1306, 1994.
J. Biol. Chem., 266(25): 16472-16477, 1991.
J. Immunol., 150(12): 5673-5681, 1993.
Dardenne M et al. Prolactin receptor expression in human hematopoietic tissues analyzed by flow cytofluorometry. Endocrinology 134:2108-14 (1994).
Rui H et al. JAK2 activation and cell proliferation induced by antibody-mediated prolactin receptor dimerization. Endocrinology 135:1299-306 (1994).
Gagnerault MC et al. Expression of prolactin receptors in murine lymphoid cells in normal and autoimmune situations. J Immunol 150:5673-81 (1993).
Dardenne M et al. Identification and functional activity of prolactin receptors in thymic epithelial cells. Proc Natl Acad Sci U S A 88:9700-4 (1991).
Rozakis-Adcock M & Kelly PA Mutational analysis of the ligand-binding domain of the prolactin receptor. J Biol Chem 266:16472-7 (1991).
Okamura H et al. Characterization and applications of monoclonal antibodies to the prolactin receptor. Endocrinology 124:2499-508 (1989).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Prolactin receptor antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-PRLR rabbit polyclonal antibody. (TA590773) Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Prolactin receptor antibody

Prolactin receptor Mouse IgG1 B6.2 Purified Hu C, F, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Prolactin receptor Mouse IgG1 B6.2 Purified Hu C, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Prolactin receptor Mouse IgG1 B6.2 Purified Hu C, F, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Prolactin receptor Mouse IgG1 PRLR742 Purified Hu C, F, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Prolactin receptor Mouse IgG1 PRLR742 Purified Hu C, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Prolactin receptor Mouse IgG1 PRLR742 Purified Hu C, F, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Prolactin receptor Mouse IgG1 B6.2+PRLR742 Purified Hu C, F, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Prolactin receptor Mouse IgG1 B6.2+PRLR742 Purified Hu C, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Prolactin receptor Mouse IgG1 B6.2+PRLR742 Purified Hu C, F, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Prolactin receptor Mouse IgG1 SPM213 Purified Hu C, F, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Prolactin receptor Mouse IgG1 SPM213 Purified Hu C, F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Prolactin receptor Mouse IgG1 SPM213 Purified Hu C, F, ICC/IF, IP, P, WB
20 µg / €160.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Sample (30 ug of whole cell lysate). A: 293T. B: HeLa. 7.5% SDS PAGE. TA308409 diluted at 1:1000. Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Prolactin receptor antibody

PRLR Antibody (Center) (Cat. #TA328160) western blot analysis in MCF-7 cell line and human placenta tissue lysates (35ug/lane).This demonstrates the PRLR antibody detected the PRLR protein (arrow). Rabbit Purified Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Prolactin receptor (25-29) antibody

Western blot analysis of extracts from 293T cells expressing human PRLR protein using PRLR Antibody AP26068PU-N. Rabbit Aff - Purified Hu WB
0.1 ml / €270.00
  Acris Antibodies GmbH

Prolactin receptor (25-29) antibody

Western blot analysis of extracts from 293T cells expressing human PRLR protein using PRLR Antibody AP26068PU-N. Rabbit Aff - Purified Hu WB
50 µl / €230.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Prolactin receptor Sheep Purified Hu, Ms, Rt E, WB
1 ml / €300.00
  Acris Antibodies GmbH

Prolactin receptor antibody

Western Blot analysis of PRLR expression in transfected 293T cell line (H00005618-T01) by PRLR MaxPab polyclonal antibody.

Lane 1: PRLR transfected lysate(68.42 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Prolactin receptor antibody

Western Blot analysis of PRLR expression in transfected 293T cell line (H00005618-T02) by PRLR MaxPab polyclonal antibody.

Lane 1: PRLR transfected lysate(69.50 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

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