Prostasin / PRSS8 antibody

Principal name

Prostasin / PRSS8 antibody

Alternative names for Prostasin / PRSS8 antibody

Serine protease 8

SwissProt ID

Q16651 (Human), Q9ES87 (Rat), Q9ESD1 (Mouse)

Gene ID

5652 (PRSS8), 192107 (Prss8)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of Prostasin / PRSS8 antibody

Prostasin is a protein that in humans is encoded by the PRSS8 gene. It is a single-copy gene and mapped to 16p11.2. Prostasin is likely to be the more physiologically relevant protease. This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. Coexpression of Prostasin with either Xenopus or rat ENaC in Xenopus oocytes resulted in a 60% to 80% increase in amiloride-sensitive sodium currents, and that the addition of aprotinin, a serine protease inhibitor, completely prevented this activation. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.

General readings

Chen M, Fu YY, Lin CY, et al. (2007). "Prostasin induces protease-dependent and independent molecular changes in the human prostate carcinoma cell line PC-3.". Biochim. Biophys. Acta 1773 (7): 1133–40.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Prostasin / PRSS8 (Center) antibody

  Rabbit polyclonal Anti-PRSS8 Antibody  
WB Suggested Anti-PRSS8 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Jurkat cell lysate Rabbit Aff - Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Prostasin / PRSS8 antibody

  Rabbit Polyclonal Anti-PRSS8 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using (PRSS8 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Prostasin / PRSS8 antibody

PRSS8 polyclonal antibody (A01), Lot # 060529JCS1. Western Blot analysis of PRSS8 expression in human ovary cancer. Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Prostasin / PRSS8 antibody

Western Blot analysis of PRSS8 expression in transfected 293T cell line (H00005652-T01) by PRSS8 MaxPab polyclonal antibody.

Lane 1: PRSS8 transfected lysate(37.73 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Prostasin / PRSS8 antibody

Western Blot analysis of PRSS8 expression in transfected 293T cell line (H00005652-T01) by PRSS8 MaxPab polyclonal antibody.

Lane 1: PRSS8 transfected lysate(36.40 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Prostasin / PRSS8 antibody

Prostasin / PRSS8 Mouse IgM 3C4 Ascites Hu, Ms, Rt E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

Prostasin / PRSS8 (Center) antibody

Human Jurkat; WB Suggested Anti-PRSS8 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Jurkat cell lysate; PRSS8 antibody - middle region (ARP56449_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

PRSS8 - human gene knockout kit via CRISPR

PRSS8 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PRSS8 - human gene knockout kit via CRISPR

PRSS8 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PRSS8 - human gene knockout kit via CRISPR

PRSS8 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PRSS8 - human gene knockout kit via CRISPR

PRSS8 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Prostasin / PRSS8

Prostasin / PRSS8 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Prostasin / PRSS8

Prostasin / PRSS8 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Prostasin / PRSS8

Prostasin / PRSS8 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Prostasin / PRSS8

Prostasin / PRSS8 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

PRSS8 (Human) IP-WB Antibody Pair

PRSS8 (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

ELISA Kits

Catalog No.    

Human Prostasin ELISA Kit

Human Prostasin ELISA Kit  
1 kit / €389.00
  OriGene Technologies, Inc.

Human Prostasin ELISA Kit

Representative Standard Curve  
96 Tests / €450.00
  Cohesion Biosciences Ltd.

Mouse Prostasin ELISA Kit

Representative Standard Curve  
96 Tests / €450.00
  Cohesion Biosciences Ltd.

Lysates

Catalog No.    

PRSS8 293T Cell Transient Overexpression Lysate(Denatured)

PRSS8 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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