Prostasin / PRSS8 antibody

Principal name

Prostasin / PRSS8 antibody

Alternative names for Prostasin / PRSS8 antibody

Serine protease 8

SwissProt ID

Q16651 (Human), Q9ES87 (Rat), Q9ESD1 (Mouse)

Gene ID

5652 (PRSS8), 192107 (Prss8)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of Prostasin / PRSS8 antibody

Prostasin is a protein that in humans is encoded by the PRSS8 gene. It is a single-copy gene and mapped to 16p11.2. Prostasin is likely to be the more physiologically relevant protease. This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. Coexpression of Prostasin with either Xenopus or rat ENaC in Xenopus oocytes resulted in a 60% to 80% increase in amiloride-sensitive sodium currents, and that the addition of aprotinin, a serine protease inhibitor, completely prevented this activation. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.

General readings

Chen M, Fu YY, Lin CY, et al. (2007). "Prostasin induces protease-dependent and independent molecular changes in the human prostate carcinoma cell line PC-3.". Biochim. Biophys. Acta 1773 (7): 1133–40.

11 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Prostasin / PRSS8 (Center) antibody

  Rabbit polyclonal Anti-PRSS8 Antibody  
WB Suggested Anti-PRSS8 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Jurkat cell lysate Rabbit Aff - Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Prostasin / PRSS8 antibody

  Rabbit Polyclonal Anti-PRSS8 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using (PRSS8 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

PRSS8 - human gene knockout kit via CRISPR

PRSS8 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PRSS8 - human gene knockout kit via CRISPR

PRSS8 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PRSS8 - human gene knockout kit via CRISPR

PRSS8 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PRSS8 - human gene knockout kit via CRISPR

PRSS8 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

ELISA Kits

Catalog No.    

Human Prostasin ELISA Kit

Human Prostasin ELISA Kit  
1 kit / €389.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PRSS8 (mGFP-tagged)-Human protease, serine, 8 (PRSS8), 200 uL, >10^7 TU/mL

Lenti ORF particles, PRSS8 (mGFP-tagged)-Human protease, serine, 8 (PRSS8), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, PRSS8 (Myc-DDK-tagged)-Human protease, serine, 8 (PRSS8), 200 uL, >10^7 TU/mL

Lenti ORF particles, PRSS8 (Myc-DDK-tagged)-Human protease, serine, 8 (PRSS8), 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Prss8 (GFP-tagged ORF) - Rat protease, serine, 8 (prostasin) (Prss8), 200 uL, >10^7 TU/mL

Lenti ORF particles, Prss8 (GFP-tagged ORF) - Rat protease, serine, 8 (prostasin) (Prss8), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Prss8 (Myc-DDK-tagged ORF) - Rat protease, serine, 8 (prostasin) (Prss8), 200 uL, >10^7 TU/mL

Lenti ORF particles, Prss8 (Myc-DDK-tagged ORF) - Rat protease, serine, 8 (prostasin) (Prss8), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

11 Item(s)

per page
  • LinkedIn