Protachykinin-1 (TAC1) antibody

Principal name

Protachykinin-1 (TAC1) antibody

Alternative names for Protachykinin-1 (TAC1) antibody

NKA, NKNA, TAC2, PPT

SwissProt ID

P01289 (Bovin), P06767 (Rat), P20366 (Human), P41539 (Mouse), P41540 (Rabit)

Gene ID

6863 (TAC1), 21333 (Tac1)

Available reactivities

Hu (Human), Mam (Mammalia), Ms (Mouse), Rt (Rat), Fi (Fish), Rb (Rabbit), Por (Porcine), Can (Canine), Chk (Chicken), Fe (Feline), GP (Guinea Pig), Bov (Bovine), Mky (Monkey), Eq (Equine), Sh (Sheep), Ye (Yeast)

Available hosts

Mouse, Rabbit, Guinea Pig, Rat, Chicken

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Paraffin Sections (P), Flow Cytometry (F), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Radioimmunoassay (R)

Background of Protachykinin-1 (TAC1) antibody

Substance P (SP) is currently thought to be one of the most important neurotransmitters and neurotransmitters in the brain. It is an undecapeptide belonging to the tachykinin family, which consists of excitatory neuropeptides synthesized in neuronal and glial cells of the human central and peripheral nervous system. Substance P, Neurokinin A, Neuropeptide K, and Neuropeptide gamma are all generated by post-translation cleavage of the precursor Protachykinin-1. Substance P forms the major endogenous ligand for Neurokinin 1 Receptor. The pharmacology of Substance P has been associated with a number of neurological and psychiatric disorders, namely nociception, migraine, asthma, nausea, inflammatory bowel syndrome, urinary incontinence, anxiety and depression. It has also been linked to obesity. This antibody reacts with substance P, a bioactive peptide secreted from neurons both in the gut and central nervous system. Can be used for the localisation of Substance P in cells and tissues.

General readings

Advenier C. et al. (1997) Eur Respir J. 10:1892-1906.Bannon MJ. et al. (1992) Brain Res Mol Brain Res. 12:225-231.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Neurokinin A antibody

Neurokinin A Rabbit Serum Fi, Hu, Por, Rt C, ICC/IF, P
50 µl / €540.00
  Acris Antibodies GmbH

Protachykinin-1 (TAC1) antibody

Predicted cell location: Cytoplasm. Positive control: Human esophagus cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human esophagus cancer tissue using TAC1 antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Protachykinin-1 (TAC1) antibody

WB Suggested Anti-TAC1 Antibody; Titration: 1.0 ug/ml; Positive Control: 721_B Whole Cell Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ye WB
50 µg / €325.00
  OriGene Technologies, Inc.

Protachykinin-1 (TAC1) antibody

Western Blot analysis of TAC1 expression in transfected 293T cell line (H00006863-T04) by TAC1 MaxPab polyclonal antibody.

Lane 1: TAC1 transfected lysate(15.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Protachykinin-1 (TAC1) antibody

Protachykinin-1 (TAC1) Rabbit Hu E, R
0.4 mg / €390.00
  Abnova Taiwan Corp.

Protachykinin-1 (TAC1) antibody

Protachykinin-1 (TAC1) Rabbit Aff - Purified Hu
50 µg / €350.00
  AVIVA Systems Biology

Protachykinin-1 (TAC1) antibody

Western blot analysis of Protachykinin 1 expression in HEK293T (A); SP2/0 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rb, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Protachykinin-1 (TAC1) antibody

Western blot analysis of Protachykinin 1 expression in HEK293T (A); SP2/0 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rb, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Protachykinin-1 (TAC1) antibody

Western blot analysis of Protachykinin 1 expression in HEK293T (A); SP2/0 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rb, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Protachykinin-1 (TAC1) antibody

Immunofluorescence: Substance P Antibody [NB300-187] - Detection of Substance P in rat spinal cord dorsal horn (red fluorescence).  DAPI (blue) was used as counter stain. Guinea Pig Purified Hu, Ms, Rt C, ICC/IF, P
50 µl / €340.00
  Novus Biologicals Inc.

Substance P antibody

Substance P Rat IgG2a NC1/34 Supernatant Hu C, ICC/IF, P
0.1 ml / €480.00
  Acris Antibodies GmbH

Substance P antibody

Figure 1. Immunofluorescence of Substance P staining in Vibratome section of Rat spinal cord. The section was incubated with AM02226PU at 1/500 for 48h, followed by an appropriate secondary antibody coupled to Cyanine 5. This antibody stains SP-Positive nerve (blue) in the close vicinity of Neurons expressing Neurokinin 1 receptor (Green) and 5-Alpha Reductase (Red) in the dorsal horn laminal. Scal bar - 20µm.
Patte-Mensch C et al. (2005) Proc Natl. Acad. Sci. USA 102 (25):9044-9. Mouse IgG1 SP-DE4-21 Purified GP, Hu, Ms, Rt C, E, ICC/IF
0.1 mg / €350.00
  Acris Antibodies GmbH

Substance P antibody

Figure 1. Immunofluorescence of Substance P staining in Vibratome section of Rat spinal cord. The section was incubated with AM02226PU at 1/500 for 48h, followed by an appropriate secondary antibody coupled to Cyanine 5. This antibody stains SP-Positive nerve (blue) in the close vicinity of Neurons expressing Neurokinin 1 receptor (Green) and 5-Alpha Reductase (Red) in the dorsal horn laminal. Scal bar - 20µm.
Patte-Mensch C et al. (2005) Proc Natl. Acad. Sci. USA 102 (25):9044-9. Mouse IgG1 SP-DE4-21 Purified GP, Hu, Ms, Rt C, E, ICC/IF
10 µg / €120.00
  Acris Antibodies GmbH

Substance P antibody

Substance P Mouse IgG1 SMPS59/1 Purified Hu E, ICC/IF
0.1 mg / €570.00
  Acris Antibodies GmbH

Substance P antibody

Staining of paraffin embedded human appendix with rabbit anti Substance P (BP823). Rabbit Purified Can, Chk, Fe, Hu, Ms C, ICC/IF, P
0.5 ml / €330.00
  Acris Antibodies GmbH

Substance P antibody

Substance P Guinea Pig Serum Fi, Hu, Rb, Rt C, F
50 µl / €340.00
  Acris Antibodies GmbH

Substance P antibody

Staining with Substance P antibody Rabbit Serum Mam C, ICC/IF
0.1 ml / €390.00
  ImmunoStar Inc.

Substance P (1-11) antibody

Substance P Guinea Pig IgG Serum Hu, Ms, Rt C, ICC/IF
50 µl / €210.00
  Neuromics Antibodies

Substance P (1-11) antibody

Substance P Guinea Pig IgG Serum Hu, Ms, Rt C, ICC/IF
0.15 ml / €390.00
  Neuromics Antibodies

Substance P (1-11) antibody

Immuofluorescent detection of Affinity Purified Substance P in rat spinal cord dorsal horn (red fluorescence).   Guinea Pig IgG Aff - Purified C, ICC/IF, P
0.1 ml / €350.00
  Neuromics Antibodies

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