Protein aurora borealis antibody

Principal name

Protein aurora borealis antibody

Alternative names for Protein aurora borealis antibody

HsBora, BORA, C13orf34, FLJ22624

SwissProt ID

Q5M864 (Rat), Q6DJL7 (Xenla), Q6PGQ7 (Human), Q8BS90 (Mouse)

Gene ID

79866 (BORA)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of Protein aurora borealis antibody

Bora (Protein aurora borealis) is a key activator of Aurora Related Protein Kinase A (ARK-1), which is a centrosome-associated serine/threonine kinase that regulates centrosome maturation, bipolar spindle assembly and chromosome segregation during mitosis. Bora is localized to the nucleus until mitosis is initiated, then translocates to the cytoplasm in a Cdc2 dependent manner. Activation of Cdc2 initiates the release of Bora into the cytoplasm where it can bind and activate ARK-1. PLK1 (polo-like kinase-1) interacts with Bora to control the accessibility of its activation loop for phosphorylation and activation by ARK-1. Bora and ARK-1 cooperatively activate PLK1 and control mitotic entry. Bora mutants result in multipolar spindles in mitosis identical to those observed when ARK-1 function is blocked. Thus, the ARK1-Bora-PLK1 regulatory circuit in mammalian cells elucidates a key mechanism in cell cycle regulation. At least three isoforms of Bora are known to exist.

11 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Protein aurora borealis (C-term) antibody

Western blot analysis of Bora in mouse brain tissue lysate with Bora antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Protein aurora borealis (N-term) antibody

Western blot analysis of Bora in Jurkat cell lysate with Bora antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Protein aurora borealis (N-term) antibody

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Protein aurora borealis Control Peptide

Protein aurora borealis
50 µg / €160.00
  Acris Antibodies GmbH

Protein aurora borealis Control Peptide

Protein aurora borealis
50 µg / €160.00
  Acris Antibodies GmbH

Protein aurora borealis antibody

Protein aurora borealis Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Protein aurora borealis antibody

Protein aurora borealis Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €480.00
  Novus Biologicals Inc.

Protein aurora borealis antibody

Immunohistochemistry-Paraffin: Bora Antibody [NBP1-77013] - Mouse brain tissue with Bora antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Protein aurora borealis antibody

Immunohistochemistry-Paraffin: Bora Antibody [NBP1-77346] - Mouse brain tissue with Bora antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Protein aurora borealis

Protein aurora borealis Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Protein aurora borealis

Protein aurora borealis Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

11 Item(s)

per page
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