Protein aurora borealis antibody

Principal name

Protein aurora borealis antibody

Alternative names for Protein aurora borealis antibody

HsBora, BORA, C13orf34, FLJ22624

SwissProt ID

Q5M864 (Rat), Q6DJL7 (Xenla), Q6PGQ7 (Human), Q8BS90 (Mouse)

Gene ID

79866 (BORA), 77744 (6720463M24Rik), 306102 (Bora)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of Protein aurora borealis antibody

Bora (Protein aurora borealis) is a key activator of Aurora Related Protein Kinase A (ARK-1), which is a centrosome-associated serine/threonine kinase that regulates centrosome maturation, bipolar spindle assembly and chromosome segregation during mitosis. Bora is localized to the nucleus until mitosis is initiated, then translocates to the cytoplasm in a Cdc2 dependent manner. Activation of Cdc2 initiates the release of Bora into the cytoplasm where it can bind and activate ARK-1. PLK1 (polo-like kinase-1) interacts with Bora to control the accessibility of its activation loop for phosphorylation and activation by ARK-1. Bora and ARK-1 cooperatively activate PLK1 and control mitotic entry. Bora mutants result in multipolar spindles in mitosis identical to those observed when ARK-1 function is blocked. Thus, the ARK1-Bora-PLK1 regulatory circuit in mammalian cells elucidates a key mechanism in cell cycle regulation. At least three isoforms of Bora are known to exist.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Protein aurora borealis (C-term) antibody

  Rabbit Polyclonal Bora Antibody  
Western blot analysis of Bora in mouse brain tissue lysate with Bora antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Protein aurora borealis (N-term) antibody

  Rabbit Polyclonal Bora Antibody  
Western blot analysis of Bora in Jurkat cell lysate with Bora antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Protein aurora borealis (N-term) antibody

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

BORA - human gene knockout kit via CRISPR

BORA - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

BORA - human gene knockout kit via CRISPR

BORA - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

BORA - human gene knockout kit via CRISPR

BORA - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

BORA - human gene knockout kit via CRISPR

BORA - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bora - mouse gene knockout kit via CRISPR

Bora - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Bora - mouse gene knockout kit via CRISPR

Bora - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bora - mouse gene knockout kit via CRISPR

Bora - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bora - mouse gene knockout kit via CRISPR

Bora - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, BORA (mGFP-tagged) - Human chromosome 13 open reading frame 34 (C13orf34), 200 uL, >10^7 TU/mL

Lenti ORF particles, BORA (mGFP-tagged) - Human chromosome 13 open reading frame 34 (C13orf34), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, BORA (Myc-DDK tagged) - Human chromosome 13 open reading frame 34 (C13orf34) , 200 uL, >10^7 TU/mL

Lenti ORF particles, BORA (Myc-DDK tagged) - Human chromosome 13 open reading frame 34 (C13orf34) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, 6720463M24Rik (GFP-tagged) - Mouse RIKEN cDNA 6720463M24 gene (cDNA clone MGC:59525 IMAGE:6336038), 200 uL, >10^7 TU/mL

Lenti ORF particles, 6720463M24Rik (GFP-tagged) - Mouse RIKEN cDNA 6720463M24 gene (cDNA clone MGC:59525 IMAGE:6336038), 200 uL, >10^7 TU/mL  
200 µl / €1,170.00
  OriGene Technologies, Inc.

Lenti ORF particles, 6720463M24Rik (Myc-DDK-tagged) - Mouse RIKEN cDNA 6720463M24 gene (cDNA clone MGC:59525 IMAGE:6336038), 200 uL, >10^7 TU/mL

Lenti ORF particles, 6720463M24Rik (Myc-DDK-tagged) - Mouse RIKEN cDNA 6720463M24 gene (cDNA clone MGC:59525 IMAGE:6336038), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Bora (GFP-tagged ORF) - Rat similar to hypothetical protein FLJ22624 (RGD1309522), 200 uL, >10^7 TU/mL

Lenti ORF particles, Bora (GFP-tagged ORF) - Rat similar to hypothetical protein FLJ22624 (RGD1309522), 200 uL, >10^7 TU/mL  
200 µl / €1,160.00
  OriGene Technologies, Inc.

Lenti ORF particles, Bora (Myc-DDK-tagged ORF) - Rat similar to hypothetical protein FLJ22624 (RGD1309522), 200 uL, >10^7 TU/mL

Lenti ORF particles, Bora (Myc-DDK-tagged ORF) - Rat similar to hypothetical protein FLJ22624 (RGD1309522), 200 uL, >10^7 TU/mL  
200 µl / €1,042.00
  OriGene Technologies, Inc.

17 Item(s)

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