Protein disulfide-isomerase / PDI antibody

Principal name

Protein disulfide-isomerase / PDI antibody

Alternative names for Protein disulfide-isomerase / PDI antibody

PDI1, MFP1, TRG1, Thioredoxin-related glycoprotein 1

SwissProt ID

P17967 (Yeast)

Gene ID

850314 (PDI1)

Ncbi ID

NP_009887

Available reactivities

Ye (Yeast)

Available hosts

Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB)

Background of Protein disulfide-isomerase / PDI antibody

The three dimensional structure of many extracellular proteins is stabilized by the formation of disulphide bonds. Studies suggest that a microsomal enzyme known as Protein Disulphide Isomerase (PDI) is involved in disulphide-bond formation and isomerization, as well as the reduction of disulphide bonds in proteins. PDI, which catalyses disulphide interchange between thiols and protein dilsulphides, has also been referred to as thiol:protein-disulphide oxidoreductase and as glutathione:insulin transhydrogenase because of its role in reduction of disulphide bonds. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the carboxy-terminus of PDI and other soluble endoplasmic reticulum (ER) resident proteins including the 78 and 94 kDa glucose regulated proteins (GRP78 and GRP94 respectively). The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Protein disulfide-isomerase / PDI antibody

Protein disulfide-isomerase / PDI Mouse IgG1 PDI-38H8 Ye ICC/IF, WB
0.2 ml / €340.00
  Acris Antibodies GmbH

Protein disulfide-isomerase / PDI antibody

Protein disulfide-isomerase / PDI Mouse IgG1 38H8 Ye ICC/IF, WB
0.2 ml / €560.00
  Abnova Taiwan Corp.

Protein disulfide-isomerase / PDI antibody

Western Blot: Pdi1p Antibody (38H8) [NBP1-05391] - Western Blot analysis of whole yeast protein extracts detected Pdi1p.  Molecular weight detected is 58.2 kDa. Mouse IgG1 38H8 Purified Ye ICC/IF, WB
0.5 ml / €360.00
  Novus Biologicals Inc.

3 Item(s)

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