Protein phosphatase 1A / PPM1A antibody

Principal name

Protein phosphatase 1A / PPM1A antibody

Alternative names for Protein phosphatase 1A / PPM1A antibody

PPPM1A, Protein phosphatase 2C isoform alpha, PP2C-alpha, Protein phosphatase IA

SwissProt ID

O62829 (Bovin), P20650 (Rat), P35813 (Human), P35814 (Rabit), P49443 (Mouse)

Gene ID

5494 (PPM1A)

Available reactivities

Hu (Human), Ms (Mouse), Mam (Mammalia), Rt (Rat), Bov (Bovine), Rb (Rabbit), Can (Canine), Chk (Chicken), Ze (Zebrafish), African clawed frog, GP (Guinea Pig), Por (Porcine)

Available hosts

Mouse, Goat, Rabbit, Sheep

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection))

Background of Protein phosphatase 1A / PPM1A antibody

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]. Transcript Variant: This variant (1) is the longest transcript and encodes isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Das, A. K. et al. (1996) EMBO J. 15, 6798-6809.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PPM1A/PPM1B antibody

PPM1A/PPM1B Rabbit IgG Bov, Hu, Ms, Rb, Rt IP, WB
0.1 mg / €560.00
  Abnova Taiwan Corp.

Protein phosphatase 1A / PPM1A antibody

WB Suggested Anti-PPM1A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Protein phosphatase 1A / PPM1A antibody

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 4E11 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

Protein phosphatase 1A / PPM1A antibody

Immunoblot analysis Mouse liver cytosol extract was resolved by electrophoresis, transferred to PVDF membrane and probed with anti-PP2C-alpha (1/250). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a DAP detection system. Arrow indicates PP2C-alpha(~43kDa) Mouse IgG2b p6c7 Purified Hu, Ms E, IP, P, WB
0.1 ml / €290.00
  Acris Antibodies GmbH

Protein phosphatase 1A / PPM1A antibody

Immunoblot analysis Mouse liver cytosol extract was resolved by electrophoresis, transferred to PVDF membrane and probed with anti-PP2C-alpha (1/250). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a DAP detection system. Arrow indicates PP2C-alpha(~43kDa) Mouse IgG2b p6c7 Purified Hu, Ms E, IP, P, WB
50 µl / €230.00
  Acris Antibodies GmbH

Protein phosphatase 1A / PPM1A antibody

Protein phosphatase 1A / PPM1A Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Protein phosphatase 1A / PPM1A antibody

Immunoperoxidase of monoclonal antibody to PPM1A on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml] Mouse IgG2a 4E11 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Protein phosphatase 1A / PPM1A antibody

Immunoblot analysis of mouse liver cytosol extract was resolved by electrophoresis , transferred to PVDF membrane and probed with PPM1A monoclonal antibody , clone p6c7 ( 1 : 250 ) ( Cat # MAB1050 ) . Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and a DAP detection system. Arrow indicates PPM1A ( ~ 43 kDa ) . Mouse IgG2b p6c7 Hu, Ms E, IP, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Protein phosphatase 1A / PPM1A antibody

Western blotting of PP2C polyclonal antibody ( Cat # PAB10354 ) in total rat brain extract. Blocked with specific peptide (+). Note: PP2C polyclonal antibodyalso readily detects recombinant PP2C alpha and PP2C beta. Rabbit Bov, Hu, Ms, Rt IP, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Protein phosphatase 1A / PPM1A antibody

Protein phosphatase 1A / PPM1A Sheep Bov, Hu, Ms, Rt IP, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Protein phosphatase 1A / PPM1A antibody

Human Heart; WB Suggested Anti-PPM1A Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human heart; PPM1A antibody - middle region (ARP57765_P050) in Human Heart cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rb, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

Protein phosphatase 1A / PPM1A antibody

Immunohistochemistry: PP2C alpha Antibody (EP1684Y) [NB110-66668] - Immunohistochemical analysis of paraffin-embedded human gastric carcinoma using anti-PP2C-alpha. Rabbit IgG EP1684Y Hu, Ms, Rt F, ICC/IF, IP, P, WB
0.1 ml / €480.00
  Novus Biologicals Inc.

Protein phosphatase 1A / PPM1A antibody

Protein phosphatase 1A / PPM1A Mouse IgG2b p6c7 Purified Hu, Ms E, IP, WB
0.1 ml / €380.00
  Novus Biologicals Inc.

Protein phosphatase 1A / PPM1A antibody

Western Blot:  PPM1A Antibody [NBP1-32751] - (30 ug of whole cell lysate) A: Raji  10% SDS PAGE diluted at 1:1000 Rabbit IgG Hu ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Protein phosphatase 1A / PPM1A (transcript variant 1)

Protein phosphatase 1A / PPM1A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Protein phosphatase 1A / PPM1A (transcript variant 3)

Protein phosphatase 1A / PPM1A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Protein phosphatase 1A / PPM1A (transcript variant 1)

Protein phosphatase 1A / PPM1A Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €299.00
  OriGene Technologies, Inc.

Protein phosphatase 1A / PPM1A (1-382, His-tag)

Protein phosphatase 1A / PPM1A Human Purified > 95 % by SDS-PAGE E. coli
0.1 mg / €230.00
  Acris Antibodies GmbH

Protein phosphatase 1A / PPM1A (1-382, His-tag)

Protein phosphatase 1A / PPM1A Human Purified > 95 % by SDS-PAGE E. coli
0.5 mg / €540.00
  Acris Antibodies GmbH

Protein phosphatase 1A / PPM1A

Protein phosphatase 1A / PPM1A Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

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