Protein phosphatase 1D / PPM1D antibody

Principal name

Protein phosphatase 1D / PPM1D antibody

Alternative names for Protein phosphatase 1D / PPM1D antibody

Protein phosphatase 2C isoform delta, PP2C-delta, WIP1, Protein phosphatase magnesium-dependent 1 delta, p53-induced protein phosphatase 1

SwissProt ID

O15297 (Human), Q9QZ67 (Mouse)

Gene ID

8493 (PPM1D)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of Protein phosphatase 1D / PPM1D antibody

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. The expression of this gene is induced in a p53-dependent manner in response to various environmental stresses. While being induced by tumor suppressor protein TP53/p53, this phosphatase negatively regulates the activity of p38 MAP kinase, MAPK/p38, through which it reduces the phosphorylation of p53, and in turn suppresses p53-mediated transcription and apoptosis. This phosphatase thus mediates a feedback regulation of p38-p53 signaling that contributes to growth inhibition and the suppression of stress induced apoptosis. This gene is located in a chromosomal region known to be amplified in breast cancer. The amplification of this gene has been detected in both breast cancer cell line and primary breast tumors, which suggests a role of this gene in cancer development.

14 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Protein phosphatase 1D / PPM1D antibody

Western blot analysis of extracts of various cell lines, using PPM1D antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Protein phosphatase 1D / PPM1D antibody

Western blot analysis of PPM1D in 3T3 cell lysate with PPM1D antibody at 1 ug/mL. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Protein phosphatase 1D / PPM1D antibody

ELISA: PPM1D Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

Protein phosphatase 1D / PPM1D (C-term) antibody

The anti-PPM1D Pab is used in Western blot to detect PPM1D in 293 cell lysate. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Protein phosphatase 1D / PPM1D antibody

Western Blot analysis of PPM1D expression in transfected 293T cell line by PPM1D monoclonal antibody (M01), clone 4D1.

Lane 1: PPM1D transfected lysate(66.7 KDa).
Lane 2: Non-transfected lysate. Mouse IgG1 4D1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Protein phosphatase 1D / PPM1D antibody

The PPM1D polyclonal antibody ( Cat # PAB2151 ) is used in Western blot to detect PPM1D in 293 cell lysate. Rabbit Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

Protein phosphatase 1D / PPM1D antibody

ELISA: PPM1D Antibody [28930002] Rabbit Hu E
50 µg / €440.00
  Novus Biologicals Inc.

Protein phosphatase 1D / PPM1D antibody

Western Blot and Immunoprecipitation: PPM1D Antibody [NB100-2110] - Detection of Human PPM1D on HeLa whole cell lysate using NB100-2110. PPM1D was also immunoprecipitated by another rabbit anti-PPM1D antibody. Rabbit Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

Protein phosphatase 1D / PPM1D antibody

Immunohistochemistry-Paraffin: PPM1D Antibody [NBP1-87249] Immunohistochemical staining of human liver shows strong nuclear and cytoplasmic positivity in hepatocytes. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Protein phosphatase 1D / PPM1D

Protein phosphatase 1D / PPM1D Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Protein phosphatase 1D / PPM1D

Protein phosphatase 1D / PPM1D Human
2 µg / €300.00
  Abnova Taiwan Corp.

Protein phosphatase 1D / PPM1D

Protein phosphatase 1D / PPM1D Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Protein phosphatase 1D / PPM1D

Protein phosphatase 1D / PPM1D Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PPM1D overexpression lysate

PPM1D overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

14 Item(s)

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