Protein S / PROS1 antibody

Principal name

Protein S / PROS1 antibody

Alternative names for Protein S / PROS1 antibody

PROS, Vitamin K-dependent protein S

SwissProt ID

P07224 (Bovin), P07225 (Human), P29617 (Drome), P53813 (Rat), Q08761 (Mouse)

Gene ID

5627 (PROS1), 19128 (Pros1), 81750

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Por (Porcine), Rb (Rabbit), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig)

Available hosts

Sheep, Mouse, Rabbit, Goat, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunodiffusion (ID), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of Protein S / PROS1 antibody

Protein S is a vitamin K dependent plasma glycoprotein (MW 69,000) which belongs to a group of coagulation inhibitors consisting itself of proteinases. It circulates in the blood in a free active form and in an inactive form bound to C4b binding protein. Protein S is also released by thrombin stimulation from platelet alpha-granules.
Protein S acts a s a cofactor for activated protein C (pCa) enhancing the cleavage of factors Va and VIIIa, producing anticoagulation by decreasing the conversion of prothrombin to thrombin. It also stimulates the fibrinolytic system. Protein S looses much of its coagulant cofactor activity after cleavage by thrombin, a process which is inhibited by thrombomodulin in the presence of free calcium ions.
Plasma concentration of protein S may be significantly reduced below normal adult levels (2.5 mg/ml) in patients with hereditary deficiency of protein S or suffering a combination of deep vein thrombosis, superficial thrombophlebitis and pulmonary embolism. Substances such as bacterial endotoxins, tumour necrosis factor and immune mediator interleukin 1 also reduce the protein S level in plasma. Oral contraceptives also depress pS activity. A reduction in plasma protein S during pregnancy usually returns to normal after parturition.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Protein S / PROS1 antibody

  Rabbit polyclonal antibody to protein S (alpha) (protein S (alpha))  
Sample (30 ug of whole cell lysate). A: 293T. 7.5% SDS PAGE. TA308822 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Protein S / PROS1 antibody

  Anti-PROS1 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human cervical and thyroid cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human cervical cancer tissue using PROS1 antibody at dilution 1/60, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Protein S / PROS1 antibody

  Anti-PROS1 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human thyroid and lung cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human thyroid cancer tissue using PROS1 antibody at dilution 1/40, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Protein S / PROS1 antibody

  Rabbit polyclonal Anti-PROS1 Antibody  
WB Suggested Anti-PROS1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Muscle Rabbit IgG Purified Can, Eq, GP, Hu, Ms P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Protein S / PROS1 antibody

  Rabbit polyclonal Anti-Pros1 Antibody  
WB Suggested Anti-Pros1 Antibody; Titration: 1.0 ug/ml; Positive Control: Rat Muscle Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Protein S / PROS1 antibody

Protein S / PROS1 Rat IgG2a PS7 FITC Hu WB
0.1 mg / €500.00
  Acris Antibodies GmbH

Protein S / PROS1 antibody

Protein S / PROS1 Rat IgG2a PS7 Purified Hu WB
0.1 mg / €400.00
  Acris Antibodies GmbH

Protein S / PROS1 antibody

Protein S / PROS1 Goat Serum Hu ID, IP
1 ml / €440.00
  Acris Antibodies GmbH

Protein S / PROS1 antibody

Protein S / PROS1 Sheep Ig Fraction E, WB
1 ml / €350.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

PROS1 - human gene knockout kit via CRISPR

PROS1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PROS1 - human gene knockout kit via CRISPR

PROS1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PROS1 - human gene knockout kit via CRISPR

PROS1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PROS1 - human gene knockout kit via CRISPR

PROS1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pros1 - mouse gene knockout kit via CRISPR

Pros1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Pros1 - mouse gene knockout kit via CRISPR

Pros1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Pros1 - mouse gene knockout kit via CRISPR

Pros1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Protein S / PROS1

  Recombinant protein of human protein S (alpha) (PROS1)  
Protein S / PROS1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Protein S / PROS1

Protein S / PROS1 Human > 95 % pure by SDS-PAGE.
Single band at 69 kDa on SDS-PAGE gels, and a doublet upon incubation with 2-mercaptoethanol.
Plasma
50 µg / €240.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PROS1 (mGFP-tagged) - Human protein S (alpha) (PROS1), 200 uL, >10^7 TU/mL

Lenti ORF particles, PROS1 (mGFP-tagged) - Human protein S (alpha) (PROS1), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, PROS1 (Myc-DDK tagged) - Human protein S (alpha) (PROS1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, PROS1 (Myc-DDK tagged) - Human protein S (alpha) (PROS1) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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