Proteoglycan 4 antibody

Principal name

Proteoglycan 4 antibody

Alternative names for Proteoglycan 4 antibody

Lubricin, PRG4, MSF, SZP, Megakaryocyte-stimulating factor, Superficial zone proteoglycan

SwissProt ID

Q92954 (Human), Q9JM99 (Mouse)

Gene ID

10216 (PRG4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C)

Background of Proteoglycan 4 antibody

Lubricin, also designated proteoglycan-4 or megakaryocyte stimulating factor, is important for boundary lubrication within articulating joints. It is a disulfide-linked homodimer (between Cysteine 1146 and Cysteine 1403) that is essential for protein cleavage. Lubricin inhibits synovial cell adhesion to the cartilage surface, but also prevents the deposition of proteins from synovial fluid onto cartilage. Lubricin is highly expressed in cartilage, liver and synovial tissue. Defects in the gene encoding for lubricin can cause Jakobs syndrome, also designated camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP). CACP is an autosomal recessive disorder characterized by joint failure associated with noninflammatory synoviocyte hyperplasia and subinitimal fibrosis of the synovial capsule. Lubricin undergoes different levels of glycosylation and may be detected at varying molecular weights.

8 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Proteoglycan 4 antibody

Proteoglycan 4 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

Proteoglycan 4 antibody

Immunofluorescence of monoclonal antibody to PRG4 on HeLa cell . [antibody concentration 10 ug/ml] Mouse IgG2a 2A6 Purified Hu E, ICC/IF
50 µg / €370.00
  Abnova Taiwan Corp.

Proteoglycan 4 antibody

Proteoglycan 4 Mouse IgG2a 2A6 Ascites Hu E
0.2 ml / €370.00
  Abnova Taiwan Corp.

Proteoglycan 4 antibody

Detection limit for recombinant GST tagged PRG4 is approximately 3ng/ml as a capture antibody. Mouse IgG2a 1D5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Proteoglycan 4 antibody

Proteoglycan 4 Goat Hu E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Proteoglycan 4 antibody

Western Blot: Lubricin Antibody [NB100-74453] - Figure 1 shows a Western blot of Lubricin in human recombinant Lubricin using NB100-74453. Rabbit Aff - Purified Hu WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteoglycan 4 antibody

Proteoglycan 4 Rabbit Serum Hu, Ms P, WB
0.2 ml / €400.00
  Novus Biologicals Inc.

Proteoglycan 4 antibody

Immunohistochemistry-Paraffin: Proteoglycan 4 Antibody [NBP1-89984] Immunohistochemical staining of human rectum shows strong cytoplasmic and nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

8 Item(s)

per page
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