PRPF3 antibody

Principal name

PRPF3 antibody

Alternative names for PRPF3 antibody

HPRP3, PRP3, Pre-mRNA-splicing factor 3, U4/U6 snRNP 90 kDa protein, U4/U6 small nuclear ribonucleoprotein Prp3

SwissProt ID

O43395 (Human), Q2KIA6 (Bovin), Q5ZJ85 (Chick), Q922U1 (Mouse)

Gene ID

9129 (PRPF3)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rt (Rat), African clawed frog, Hst (Hamster), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PRPF3 antibody

Retinitis pigmentosa (RP) is an inheritable disease characterized by progressive retinal degeneration and loss of rod photoreceptor cells, leading to total blindness. Recently three genes responsible for autosomal dominant RP (HPRP3, PRPF31, and PRPC8) have been identified as the human orthologues of the yeast genes PRP3, PRP31, and PRP8, respectively. The removal of introns from nuclear pre-mRNAs occurs on spliceosomes, which consist of 4 small nuclear ribonucleoprotein (snRNP) particles and a number of transiently associated splicing factors. All three PRP (pre-mRNA processing factor) genes are involved in the function of the U4/U6,U5 tri-snRNP, the spliceosome component required for the transition to a catalytically active state. In mammals, the 63 kDa HPRP3 is thought to recruit HPRP4 to the U4/U6 snRNP. In yeast, PRP3 and PRP4 genetically interact, and physical interactions between Prp3p and Prp4p proteins are required for association of Prp3p and Prp4p with U4/U6.

General readings

Rual,J.F., (2005) Nature 437 (7062), 1173-1178

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PRPF3 antibody

Western blot analysis of extracts of various cell lines, using PRPF3 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

PRPF3 antibody

WB Suggested Anti-PRPF3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

PRPF3 antibody

Immunocytochemical detection of Prp3 on HEp-Ⅱ cells using AM26502AF-N. Rat IgG2a 4E3 Azide Free Hst, Hu, Ms, Rt ICC/IF, IP, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

PRPF3 antibody

PRPF3 monoclonal antibody (M01), clone 3H6 Western Blot analysis of PRPF3 expression in Hela NE ( Cat # L013V3 ). Mouse IgG3 3H6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PRPF3 antibody

PRPF3 Mouse IgG3 3H6 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

PRPF3 antibody

Human HepG2; WB Suggested Anti-PRPF3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: HepG2 cell lysate; PRPF3 antibody - N-terminal region (ARP40543_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

PRPF3 antibody

Immunohistochemistry-Paraffin: PRPF3 Antibody [NBP1-19114] - See Notes, IHC Caption B Rabbit IgG Aff - Purified Hu IP, P
0.1 ml / €440.00
  Novus Biologicals Inc.

PRPF3 antibody

PRPF3 Rabbit Aff - Purified Can, Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

PRPF3 antibody

Immunohistochemistry-Paraffin: PRPF3 Antibody [NBP1-83219] - Immunohistochemical staining of human skeletal muscle shows strong cytoplasmic positivity in subsets of muscle fibers. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PRPF3

PRPF3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PRPF3

PRPF3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PRPF3 overexpression lysate

PRPF3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

12 Item(s)

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