PRPF8 antibody

Principal name

PRPF8 antibody

Alternative names for PRPF8 antibody

Pre-mRNA-processing-splicing factor 8, PRPC8, Splicing factor Prp8, PRP8 homolog, 220 kDa U5 snRNP-specific protein

SwissProt ID

P33334 (Yeast), P34369 (Caeel), Q6P2Q9 (Human), Q99PV0 (Mouse)

Gene ID

10594 (PRPF8), 192159 (Prpf8)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Dros (Drosophila), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB)

Background of PRPF8 antibody

Pre-mR splicing occurs in 2 sequential transesterification steps. PRPF8 is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mR splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. The gene encoding PRPF8 is a candidate gene for autosomal domint retinitis pigmentosa.Pre-mR splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mR splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal domint retinitis pigmentosa. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

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