PRUNE antibody

Principal name

PRUNE antibody

Alternative names for PRUNE antibody

Protein prune homolog, hPrune, HTcD37, DRES17, DRES-17, Drosophila-related expressed sequence 17

SwissProt ID

Q5E9Y6 (Bovin), Q6AYG3 (Rat), Q86TP1 (Human), Q8BIW1 (Mouse), Q9C071 (Human)

Gene ID

58497 (PRUNE)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P), Flow Cytometry (F)

Background of PRUNE antibody

PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune; h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness.

General readings

Vieira, A.R., et al. Genet. Med. 10(9): 668-674 (2008)
Middelhaufe, S., et al. Biochem. J. 407(2): 199-205 (2007)
Kobayashi, T., et al. Mol. Cell. Biol. 26(3): 898-911 (2006)
Zollo, M., et al. Clin. Cancer Res. 11(1): 199-205 (2005)
Forus, A., et al. Oncogene 20(47): 6881-6890 (2001)
Reymond, A., et al. Oncogene 18(51): 7244-7252 (1999)

  1. Quick-Filters:
  2. Highly Validated (1)

11 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PRUNE antibody

Immunofluorescence of purified MaxPab antibody to PRUNE on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu, Ms E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

PRUNE antibody

Host: Rabbit; Target Name: PRUNE; Sample Tissue: COLO205 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

PRUNE antibody

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 1C11 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

PRUNE (C-term) antibody

Immunohistochemistry analysis in prostate carcinoma (Formalin-fixed, Paraffin-embedded) using PRUNE antibody Cat.-No. AP53474PU-N (C-term), followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PRUNE Antibody (C-term) for IHC; Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PRUNE antibody

PRUNE Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PRUNE antibody

PRUNE Mouse IgG2a 1C11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PRUNE antibody

Immunohistochemistry-Paraffin: PRUNE Antibody [NBP1-84055] - Immunohistochemical staining of human esophagus shows distinct cytoplasmic positivity in squamous epithelial cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PRUNE

PRUNE Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PRUNE

PRUNE Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PRUNE 293T Cell Transient Overexpression Lysate(Denatured)

PRUNE 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

PRUNE overexpression lysate

PRUNE overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

11 Item(s)

per page
  • LinkedIn