PSMA1 antibody

Principal name

PSMA1 antibody

Alternative names for PSMA1 antibody

Proteasome subunit alpha type-1, Proteasome 20S C2, Macropain subunit C2, Proteasome component C2, Proteasome nu chain, HC2, NU, PROS30, PROS-30, PSC2, Multicatalytic endopeptidase complex subunit C2

SwissProt ID

O14250 (Schpo), O42265 (Chick), O44156 (Caeel), P12881 (Drome), P18420 (Rat), P25786 (Human), P40302 (Yeast), Q3T0X5 (Bovin), Q9R1P4 (Mouse)

Gene ID

5682 (PSMA1)

Available reactivities

Can (Canine), Hst (Hamster), Hu (Human), Ms (Mouse), Rt (Rat), Chk (Chicken), Bov (Bovine), Dros (Drosophila), African clawed frog, Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ye (Yeast)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of PSMA1 antibody

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA1 is a member of the peptidase T1A family which is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.

General readings

General / background references:Schwartz AL & Ciechanover A The ubiquitin-proteasome pathway and pathogenesis of human diseases. Annu Rev Med 50:57-74 (1999). PubMed PMID: 10073263
Voges D et al. The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu Rev Biochem 68:1015-68 (1999). PubMed PMID: 10872471
1. Vishnyakova, T. G., Kurlander, R., Bocharov, A. V., et al. (2006) CLA-1 and its splicing variant CLA-2 mediate bacterial adhesion and cytosolic bacterial invasion in mammalian cells, 103, 16888-16893.
2. Laporte D, Salin B, Daignan-Fornier B, et al. Reversible cytoplasmic localization of the proteasome in quiescent yeast cells. J Cell Biol 2008;181(5):737-745.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PSMA1 antibody

Western blot analysis of extracts of various cell lines, using PSMA1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

PSMA1 antibody

Immunofluorescence of monoclonal antibody to PSMA1 on HeLa cell. [antibody concentration 60 ug/ml] Mouse IgG1 1D9-1C7 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PSMA1 antibody

WB Suggested Anti-PSMA1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PSMA1 antibody

WB Suggested Anti-PSMA1 Antibody Titration: 1.25 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PSMA1 antibody

PSMA1 Mouse IgG1 S3 Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

PSMA1 antibody

Detection limit for recombinant GST tagged PSMA1 is approximately 3ng/ml as a capture antibody. Mouse IgG1 3F12-2C9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PSMA1 antibody

Detection limit for recombinant GST tagged PSMA1 is approximately 3ng/ml as a capture antibody. Mouse IgG2a 3D8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PSMA1 antibody

Human Bronchial Epithelial Tissue; Rabbit Anti-PSMA1 Antibody . Catalog Number: ARP40417_P050 . Formalin Fixed Paraffin Embedded Tissue: Human Bronchial Epithelial Tissue . Observed Staining: Cytoplasmic . Primary Antibody Concentration: 1:100 . Secondary Antibody: Donkey anti-Rabbit-Cy3 . Secondary Antibody Concentration: 1:200 . Magnification: 20X . Exposure Time: 0.5 - 2.0 sec .; Rabbit Anti-PSMA1 Antibody (ARP40417_P050) ) in Human Bronchial Epithelial Tissue using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

PSMA1 antibody

Human Jurkat; WB Suggested Anti-PSMA1 Antibody Titration: 1.25ug/ml. Positive Control: Jurkat cell lysate; PSMA1 antibody - N-terminal region (ARP40418_T100) in Human Jurkat cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Dros, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

PSMA1 antibody

Western Blot: Proteasome 20S C2 Antibody [NB300-624] - Figure 1 shows a Western blot of 20S C2 subunit in CHO cell extract using NB300-624. Rabbit Aff - Purified Can, Chk, Hst, Hu, Ms, Rt WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PSMA1 (full length, N-term HIS tag, transcript variant 2)

PSMA1 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

PSMA1 (1-263, His-tag)

PSMA1 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

PSMA1 (1-263, His-tag)

PSMA1 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

PSMA1

PSMA1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PSMA1

PSMA1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PSMA1 overexpression lysate

PSMA1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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