PSMA3 antibody

Principal name

PSMA3 antibody

Alternative names for PSMA3 antibody

Proteasome subunit alpha type-3, Macropain subunit C8, PSC8, HC8, Proteasome component C8, Multicatalytic endopeptidase complex subunit C8

SwissProt ID

O70435 (Mouse), P18422 (Rat), P25788 (Human), P25788-2, Q58DU5 (Bovin)

Gene ID

5684 (PSMA3), 19167 (Psma3), 29670, 408248 (Psma3l)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), African clawed frog, Por (Porcine), Ze (Zebrafish), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of PSMA3 antibody

The proteasome is a multicatalytic proteise complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA3 is a member of the peptidase T1A family, that is a 20S core alpha subunit.The proteasome is a multicatalytic proteise complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two altertive transcripts encoding different isoforms have been identified.

General readings

Kristensen P., et al. (1995) Biochem Biophys Res Commun. 207(3):1059.Wenzel T., et al. (1995) Nat Struct Biol. 2(3):199-204.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PSMA3 antibody

  Rabbit polyclonal antibody to 20S Proteasome alpha3 (proteasome (prosome, macropain) subunit, alpha type, 3)  
Proteasome 20S alpha 3 antibody detects PSMA3 protein by Western blot analysis. A. 30 ug NIH-3T3 whole cell lysate/extract. B. 30 ug JC whole cell lysate/extract. C. 30 ug BCL-1 whole cell lysate/extract. 12 % SDS-PAGE. Proteasome 20S alpha 3 antibody (TA Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PSMA3 antibody

  PSMA3 Rabbit Polyclonal Antibody  
Western blot analysis of extracts from HT-29 cells, treated with heat shock, using Vitamin D Receptor (Phospho-Ser208) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

PSMA3 antibody

  Rabbit Polyclonal Anti-PSMA3 Antibody - middle region  
WB Suggested Anti-PSMA3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: Human brain Rabbit IgG Purified Can, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PSMA3 antibody

  Rabbit Polyclonal Anti-PSMA3 Antibody - middle region  
WB Suggested Anti-PSMA3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: 293T cell lysate Rabbit IgG Purified Can, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PSMA3 pSer250 antibody

Western blot analysis of extracts from NIH-3T3 cells treated with EGF 200ng/ml 30', using Proteasome alpha3 (Phospho-Ser250) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

PSMA3 pSer250 antibody

Western blot analysis of extracts from NIH-3T3 cells treated with EGF 200ng/ml 30', using Proteasome alpha3 (Phospho-Ser250) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

PSMA3 - human gene knockout kit via CRISPR

PSMA3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PSMA3 - human gene knockout kit via CRISPR

PSMA3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PSMA3 - human gene knockout kit via CRISPR

PSMA3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PSMA3 - human gene knockout kit via CRISPR

PSMA3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Psma3 - mouse gene knockout kit via CRISPR

Psma3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Psma3 - mouse gene knockout kit via CRISPR

Psma3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PSMA3 (transcript variant 1)

  Recombinant protein of human proteasome (prosome, macropain) subunit, alpha type, 3 (PSMA3), transcript variant 1  
PSMA3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

PSMA3 (1-255, His-tag)

PSMA3 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

PSMA3 (1-255, His-tag)

PSMA3 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

PSMA3 overexpression lysate

PSMA3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PSMA3 (mGFP-tagged) - Human proteasome (prosome, macropain) subunit, alpha type, 3 (PSMA3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, PSMA3 (mGFP-tagged) - Human proteasome (prosome, macropain) subunit, alpha type, 3 (PSMA3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, PSMA3 (Myc-DDK tagged) - Human proteasome (prosome, macropain) subunit, alpha type, 3 (PSMA3), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, PSMA3 (Myc-DDK tagged) - Human proteasome (prosome, macropain) subunit, alpha type, 3 (PSMA3), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Psma3 (GFP-tagged) - Mouse proteasome (prosome, macropain) subunit, alpha type 3 (Psma3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Psma3 (GFP-tagged) - Mouse proteasome (prosome, macropain) subunit, alpha type 3 (Psma3), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Psma3 (Myc-DDK-tagged) - Mouse proteasome (prosome, macropain) subunit, alpha type 3 (Psma3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Psma3 (Myc-DDK-tagged) - Mouse proteasome (prosome, macropain) subunit, alpha type 3 (Psma3), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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