PSMB11 antibody

Principal name

PSMB11 antibody

Alternative names for PSMB11 antibody

Proteasome subunit beta type-11, Proteasome subunit beta-5t

SwissProt ID

A5LHX3 (Human), Q8BG41 (Mouse)

Gene ID

122706 (PSMB11)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts


Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of PSMB11 antibody

Proteasomes generate peptides that are presented by major histocompatibility complex (MHC) I molecules to other cells of the immune system. Proteolysis is conducted by 20S proteasomes, complexes of 28 subunits arranged as a cylinder in 4 heteroheptameric rings: alpha-1 to -7, beta-1 to -7, beta-1 to -7, and alpha-1 to -7. The catalytic subunits are beta-1 (PSMB6; MIM 600307), beta-2 (PSMB7; MIM 604030), and beta-5 (PSMB5; MIM 600306). Three additional subunits, beta-1i (PSMB9; MIM 177045), beta-2i (PSMB10; MIM 176847), and beta-5i (PSMB8; MIM 177046), are induced by gamma-interferon (IFNG; MIM 147570) and are preferentially incorporated into proteasomes to make immunoproteasomes. PSMB11, or beta-5t, is a catalytic subunit expressed exclusively in cortical thymic epithelial cells (Murata et al., 2007 [PubMed 17540904]).

General readings

Tomaru, U., et al. Blood 113(21):5186-5191 (2009).
Murata, S., et al. Science 316(5829):1349-1353 (2007).

2 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PSMB11 antibody

PSMB11 Rabbit IgG Purified Hu, Rt WB
  OriGene Technologies, Inc.

PSMB11 (C-term) antibody

PSMB11 Rabbit Ig Aff - Purified Hu WB
  Acris Antibodies GmbH

2 Item(s)

per page
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