PSMB8 antibody

Principal name

PSMB8 antibody

Alternative names for PSMB8 antibody

Proteasome subunit beta type-8, Proteasome 20S LMP7, Macropain subunit C13, Proteasome component C13, Proteasome subunit beta-5i, LMP7, PSMB5i, RING10, Low molecular mass protein 7, Multicatalytic endopeptidase complex subunit C13, Really interesting new gene 10 protein, Y2

SwissProt ID

P28062 (Human), P28063 (Mouse), P28064 (Rat), Q29576 (Pig), Q3T112 (Bovin), Q5W416 (Canfa)

Gene ID

5696 (PSMB8), 16913 (Psmb8), 24968

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of PSMB8 antibody

The proteasome is a multicatalytic proteise complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two altertive transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit. [provided by RefSeq, Jul 2008].

General readings

Deshpande A, Wheeler CM, Hunt WC, Peyton CL, White PS, Valdez YE, Nolan JP.
Variation in HLA class I antigen-processing genes and susceptibility to human papillomavirus type 16-associated cervical cancer.
The Journal of Infectious Diseases 2008 Feb 197 (3): 371-81.
PMID: 18248301

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PSMB8 antibody

  Rabbit polyclonal antibody to PSMB8 (proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7))  
Sample (30 ug of whole cell lysate). A: Raji. 12% SDS PAGE. TA308731 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PSMB8 antibody

Immunohistochemical analysis of paraffin-embedded intima cancer tissues using PSMB8 mouse mAb with DAB staining. Mouse IgG1 1A5 Ascites Hu, Rt E, ICC/IF, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

PSMB8 (C-term) antibody

  Goat Anti-LMP7 Antibody  
TA305716 (0.01ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PSMB8 antibody

  Rabbit Polyclonal Anti-PSMB8 Antibody  
Host: Rabbit; Target Name: PSMB8; Sample Tissue: Hela Whole Cell lysates; Antibody Dilution: 1.0 ug/ml.PSMB8 is supported by BioGPS gene expression data to be expressed in HeLa Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

PSMB8 antibody

  Rabbit Polyclonal Anti-PSMB8 rabbit polyclonal antibody  
Gel: 8%SDS-PAGE,Lysate: 40 ug,Lane 1-6: 231 cells, A431 cells, Mouse liver tissue, Human placenta tissue, Jurkat cells, Raji cells,Primary antibody: (PSMB8 Antibody) at dilution 1/350 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 10 seconds Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

PSMB8 - human gene knockout kit via CRISPR

PSMB8 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PSMB8 - human gene knockout kit via CRISPR

PSMB8 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PSMB8 - human gene knockout kit via CRISPR

PSMB8 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PSMB8 - human gene knockout kit via CRISPR

PSMB8 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PSMB8 (transcript variant 1)

  Recombinant protein of human proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (PSMB8), transcript variant 1  
PSMB8 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PSMB8 (transcript variant 2)

  Recombinant protein of human proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (PSMB8), transcript variant 2  
PSMB8 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

PSMB8 (73-276, His-tag)

PSMB8 Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

PSMB8 (73-276, His-tag)

PSMB8 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

PSMB8 overexpression lysate

PSMB8 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PSMB8 (mGFP-tagged) - Human proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (PSMB8), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, PSMB8 (mGFP-tagged) - Human proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (PSMB8), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, PSMB8 (Myc-DDK tagged) - Human proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (PSMB8), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, PSMB8 (Myc-DDK tagged) - Human proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (PSMB8), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Psmb8 (GFP-tagged) - Mouse proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) (Psmb8), 200 uL, >10^7 TU/mL

Lenti ORF particles, Psmb8 (GFP-tagged) - Mouse proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) (Psmb8), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Psmb8 (Myc-DDK-tagged) - Mouse proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) (Psmb8), 200 uL, >10^7 TU/mL

Lenti ORF particles, Psmb8 (Myc-DDK-tagged) - Mouse proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) (Psmb8), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Psmb8 (GFP-tagged ORF) - Rat proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) (Psmb8), 200 uL, >10^7 TU/mL

Lenti ORF particles, Psmb8 (GFP-tagged ORF) - Rat proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) (Psmb8), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Psmb8 (Myc-DDK-tagged ORF) - Rat proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) (Psmb8), 200 uL, >10^7 TU/mL

Lenti ORF particles, Psmb8 (Myc-DDK-tagged ORF) - Rat proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) (Psmb8), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

20 Item(s)

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