PSMB8 antibody

Principal name

PSMB8 antibody

Alternative names for PSMB8 antibody

Proteasome subunit beta type-8, Proteasome 20S LMP7, Macropain subunit C13, Proteasome component C13, Proteasome subunit beta-5i, LMP7, PSMB5i, RING10, Low molecular mass protein 7, Multicatalytic endopeptidase complex subunit C13, Really interesting new gene 10 protein, Y2

SwissProt ID

P28062 (Human), P28063 (Mouse), P28064 (Rat), Q29576 (Pig), Q3T112 (Bovin), Q5W416 (Canfa)

Gene ID

5696 (PSMB8)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Por (Porcine), Rt (Rat), Xen (Xenopus), Ze (Zebrafish)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), Flow Cytometry (F), Immunoprecipitation (IP), Frozen Sections (C)

Background of PSMB8 antibody

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit. [provided by RefSeq]. Transcript Variant: This variant (2) differs in the 5' UTR and contains an alternate in-frame exon in the 5' coding region, compared to variant 1. Isoform E2 has a distinct N-terminus, compared to isoform E1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

General / background references:Schwartz AL & Ciechanover A The ubiquitin-proteasome pathway and pathogenesis of human diseases. Annu Rev Med 50:57-74 (1999). PubMed PMID: 10073263
Voges D et al. The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu Rev Biochem 68:1015-68 (1999). PubMed PMID: 10872471
Rechsteiner M Ubiquitin-mediated pathways for intracellular proteolysis. Annu Rev Cell Biol 3:1-30 (1987). PubMed PMID: 2825735

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PSMB8 antibody

Sample (30 ug of whole cell lysate). A: Raji. 12% SDS PAGE. TA308731 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PSMB8 antibody

Immunohistochemical analysis of paraffin-embedded intima cancer tissues using PSMB8 mouse mAb with DAB staining. Mouse IgG1 1A5 Ascites Hu, Rt E, ICC/IF, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

PSMB8 antibody

PSMB8 MaxPab rabbit polyclonal antibody. Western Blot analysis of PSMB8 expression in mouse liver. Rabbit Serum Hu, Ms E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

PSMB8 (C-term) antibody

TA305716 (0.01ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PSMB8 antibody

Host: Rabbit; Target Name: PSMB8; Sample Tissue: Hela Whole Cell lysates; Antibody Dilution: 1.0 ug/ml.PSMB8 is supported by BioGPS gene expression data to be expressed in HeLa Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

PSMB8 antibody

Immunofluorescence of purified MaxPab antibody to PSMB8 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

PSMB8 antibody

PSMB8 MaxPab rabbit polyclonal antibody. Western Blot analysis of PSMB8 expression in mouse liver. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PSMB8 antibody

Immunoperoxidase of monoclonal antibody to PSMB8 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3ug/ml] Mouse IgG2a 1B3 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PSMB8 antibody

PSMB8 Mouse IgG2a 1G7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PSMB8 antibody

PSMB8 Mouse IgG2a 2F4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PSMB8 antibody

PSMB8 Mouse IgG2a 4E4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PSMB8 antibody

Western Blot: Proteasome 20S LMP7 Antibody [NB120-3329] - Figure 1 shows a Western blot of proteasome 20S LMP7 from HeLa cell extract using NB120-3329. Rabbit IgG Aff - Purified Hu WB
0.1 mg / €400.00
  Novus Biologicals Inc.

PSMB8 antibody

Immunohistochemistry: Proteasome 20S LMP7 Antibody [NBP1-33540] - Immunohistochemical analysis of Proteasome 20S LMP7 on paraffin-embedded CaI27 xenograft, using NBP1-33540. Rabbit IgG Hu ICC/IF, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

PSMB8 antibody

PSMB8 Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PSMB8 (transcript variant 1)

PSMB8 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PSMB8 (transcript variant 2)

PSMB8 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

PSMB8 (73-276, His-tag)

PSMB8 Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

PSMB8 (73-276, His-tag)

PSMB8 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

PSMB8

PSMB8 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

PSMB8

PSMB8 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

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