PSMC3 / TBP1 antibody

Principal name

PSMC3 / TBP1 antibody

Alternative names for PSMC3 / TBP1 antibody

26S protease regulatory subunit 6A, Proteasome 26S subunit ATPase 3, Proteasome subunit P50, Tat-binding protein 1, TBP-1

SwissProt ID

O14126 (Schpo), O88685 (Mouse), P17980 (Human), P33297 (Yeast), Q63569 (Rat)

Gene ID

5702 (PSMC3)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Mky (Monkey), Xen (Xenopus)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Frozen Sections (C)

Background of PSMC3 / TBP1 antibody

PSMC3 is a subunit of the 26S proteasome. 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Thompson,H.G., et al., (2004) Int. J. Cancer 111 (3), 338-347

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PSMC3 / TBP1 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-PSMC3mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500922, Dilution 1:50) Mouse IgG1 OTI9F3 Purified Can, Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

Immunohistochemical staining of paraffin-embedded Kidney tissue within the normal limits using anti-PSMC3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500923, Dilution 1:50) Mouse IgG2b OTI6E10 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

Anti-PSMC3 mouse monoclonal antibody (TA500924) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PSMC3(RC201790). Mouse IgG2a OTI1G4 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-PSMC3mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500925, Dilution 1:50) Mouse IgG2b OTI8G10 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-PSMC3mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500926, Dilution 1:50) Mouse IgG1 OTI8D6 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-PSMC3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500928, Dilution 1:50) Mouse IgG2a OTI1C10 Purified Can, Hu, Mky, Rt ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

Immunohistochemical staining of paraffin-embedded Kidney tissue within the normal limits using anti-PSMC3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500930, Dilution 1:50) Mouse IgG2b OTI7D1 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-PSMC3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500931, Dilution 1:50) Mouse IgG1 OTI7B10 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of liver tissue using anti-PSMC3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500932, Dilution 1:50) Mouse IgG1 OTI9C11 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-PSMC3mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500933, Dilution 1:50) Mouse IgG2b OTI10D12 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

Sample (30 ug of whole cell lysate). A: MOLT4 . 10% SDS PAGE. TA308441 diluted at 1:5000 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PSMC3 / TBP1 antibody

Western blot analysis of extracts of various cell lines, using PSMC3 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

PSMC3 / TBP1 antibody

Anti-PSMC3 mouse monoclonal antibody (TA500929) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PSMC3(RC201790). Mouse IgG1 OTI9G5 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

Human kidney; PSMC3 antibody - middle region (AP42156PU-N) in Human kidney cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze P, WB
0.1 mg / €310.00
  Acris Antibodies GmbH

PSMC3 / TBP1 antibody

PSMC3 MaxPab polyclonal antibody. Western Blot analysis of PSMC3 expression in rat brain. Mouse Purified Hu, Rt E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

PSMC3 / TBP1 antibody

Western Blot analysis of PSMC3 expression in transfected 293T cell line (H00005702-T01) by PSMC3 MaxPab polyclonal antibody.

Lane 1: PSMC3 transfected lysate(49.20 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PSMC3 / TBP1 antibody

PSMC3 monoclonal antibody (M01), clone 1B9 Western Blot analysis of PSMC3 expression in HeLa ( Cat # L013V1 ). Mouse IgG1 1B9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PSMC3 / TBP1 antibody

Western blot analysis of extracts from K562/HT-29 cells, using PRS6A Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

PSMC3 / TBP1 antibody

Western blot analysis of extracts from K562/HT-29 cells, using PRS6A Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

PSMC3 / TBP1 antibody

Human kidney; PSMC3 antibody - middle region (ARP32929_T100) in Human kidney cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

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