PSMC3 / TBP1 antibody

Principal name

PSMC3 / TBP1 antibody

Alternative names for PSMC3 / TBP1 antibody

26S protease regulatory subunit 6A, Proteasome 26S subunit ATPase 3, Proteasome subunit P50, Tat-binding protein 1, TBP-1

SwissProt ID

O14126 (Schpo), O88685 (Mouse), P17980 (Human), P33297 (Yeast), Q63569 (Rat)

Gene ID

5702 (PSMC3), 29677 (Psmc3)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Mky (Monkey)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PSMC3 / TBP1 antibody

PSMC3 is a subunit of the 26S proteasome. 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Thompson,H.G., et al., (2004) Int. J. Cancer 111 (3), 338-347

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PSMC3 / TBP1 antibody

  anti-PSMC3 mouse monoclonal antibody, clone OTI9F3 (formerly 9F3)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-PSMC3mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500922, Dilution 1:50) Mouse IgG1 OTI9F3 Purified Can, Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

  anti-PSMC3 mouse monoclonal antibody, clone OTI6E10 (formerly 6E10)  
Immunohistochemical staining of paraffin-embedded Kidney tissue within the normal limits using anti-PSMC3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500923, Dilution 1:50) Mouse IgG2b OTI6E10 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

  PSMC3 mouse monoclonal antibody, clone OTI1G4 (formerly 1G4)  
Anti-PSMC3 mouse monoclonal antibody (TA500924) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PSMC3(RC201790). Mouse IgG2a OTI1G4 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

  anti-PSMC3 mouse monoclonal antibody, clone OTI8G10 (formerly 8G10)  
Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-PSMC3mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500925, Dilution 1:50) Mouse IgG2b OTI8G10 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

  anti-PSMC3 mouse monoclonal antibody, clone OTI8D6 (formerly 8D6)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-PSMC3mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500926, Dilution 1:50) Mouse IgG1 OTI8D6 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

  anti-PSMC3 mouse monoclonal antibody, clone OTI1C10 (formerly 1C10)  
Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-PSMC3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500928, Dilution 1:50) Mouse IgG2a OTI1C10 Purified Can, Hu, Mky, Rt ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

  anti-PSMC3 mouse monoclonal antibody, clone OTI7D1 (formerly 7D1)  
Immunohistochemical staining of paraffin-embedded Kidney tissue within the normal limits using anti-PSMC3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500930, Dilution 1:50) Mouse IgG2b OTI7D1 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

  anti-PSMC3 mouse monoclonal antibody, clone OTI7B10 (formerly 7B10)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-PSMC3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500931, Dilution 1:50) Mouse IgG1 OTI7B10 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

  anti-PSMC3 mouse monoclonal antibody, clone OTI9C11 (formerly 9C11)  
Immunohistochemical staining of paraffin-embedded Carcinoma of liver tissue using anti-PSMC3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500932, Dilution 1:50) Mouse IgG1 OTI9C11 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

  anti-PSMC3 mouse monoclonal antibody, clone OTI10D12 (formerly 10D12)  
Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-PSMC3mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500933, Dilution 1:50) Mouse IgG2b OTI10D12 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

  Rabbit polyclonal antibody to PSMC3 (proteasome (prosome, macropain) 26S subunit, ATPase, 3)  
Sample (30 ug of whole cell lysate). A: MOLT4 . 10% SDS PAGE. TA308441 diluted at 1:5000 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PSMC3 / TBP1 antibody

  Rabbit anti-PSMC3 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using PSMC3 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

PSMC3 / TBP1 antibody

  anti-PSMC3 mouse monoclonal antibody, clone OTI9G5 (formerly 9G5)  
Anti-PSMC3 mouse monoclonal antibody (TA500929) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PSMC3(RC201790). Mouse IgG1 OTI9G5 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PSMC3 / TBP1 antibody

Human kidney; PSMC3 antibody - middle region (AP42156PU-N) in Human kidney cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze P, WB
0.1 mg / €310.00
  Acris Antibodies GmbH

PSMC3 / TBP1 antibody

Western blot analysis of extracts from K562/HT-29 cells, using PRS6A Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

PSMC3 / TBP1 antibody

Western blot analysis of extracts from K562/HT-29 cells, using PRS6A Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

PSMC3 - human gene knockout kit via CRISPR

PSMC3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PSMC3 - human gene knockout kit via CRISPR

PSMC3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PSMC3 / TBP1

  Recombinant protein of human proteasome (prosome, macropain) 26S subunit, ATPase, 3 (PSMC3)  
PSMC3 / TBP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Psmc3 (GFP-tagged ORF) - Rat proteasome (prosome, macropain) 26S subunit, ATPase 3 (Psmc3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Psmc3 (GFP-tagged ORF) - Rat proteasome (prosome, macropain) 26S subunit, ATPase 3 (Psmc3), 200 uL, >10^7 TU/mL  
200 µl / €1,040.00
  OriGene Technologies, Inc.

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