PSMD5 antibody

Principal name

PSMD5 antibody

Alternative names for PSMD5 antibody

26S proteasome non-ATPase regulatory subunit 5, Proteasome 19S S5B, 26S protease subunit S5 basic, 26S proteasome subunit S5B, KIAA0072

SwissProt ID

Q0P5A6 (Bovin), Q16401 (Human), Q8BJY1 (Mouse)

Gene ID

5711 (PSMD5)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunoprecipitation (IP), ELISA (detection) (E(detection))

Background of PSMD5 antibody

Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes, and the endoplasmic reticulum.
The 26S proteasome is an ATP-dependent, multisubunit (~31), barrel-shaped molecular machine with an apparent molecular weight of ~2.5 MDa. It consists of a 20S proteolytic core complex which is crowned at one or both ends by 19S regulatory subunit complexes. The 19S regulatory subunits recognize ubiquitinated proteins and play an essential role in unfolding and translocating targets into the lumen of the 20S subunit. An enzymatic cascade is responsible for the attachment of multiple ubiquitin molecules to lysine residues of proteins targeted for degradation. Several genetic diseases are associated with defects in the ubiquitin-proteasome pathway. Some examples of affected proteins include those linked to cystic fibrosis, Angelman's syndrome, and Liddle syndrome.

General readings

General / background references:Schwartz AL & Ciechanover A The ubiquitin-proteasome pathway and pathogenesis of human diseases. Annu Rev Med 50:57-74 (1999). PubMed PMID: 10073263
Voges D et al. The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu Rev Biochem 68:1015-68 (1999). PubMed PMID: 10872471
Rechsteiner M Ubiquitin-mediated pathways for intracellular proteolysis. Annu Rev Cell Biol 3:1-30 (1987). PubMed PMID: 2825735

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PSMD5 antibody

Predicted band size: 56 kDa . Positive control: A431 cell and human fetal liver cancer tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lane1: A431 cell lysate Lane2: Human fetal liver cancer tissue lysate Lysates: 40 ug per lane Primary antibody: 1/150 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PSMD5 antibody

Predicted band size: 56 kDa . Positive control: Human fetal liver and muscle tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lane1: Human fetal liver tissue lysate Lane2: Human fetal muscle tissue lysate Lysates: 40 ug per lane Primary antibody: 1/150 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PSMD5 antibody

Host: Rabbit; Target Name: PSMD5; Sample Tissue: OVCAR-3 Whole Cell lysates; Antibody Dilution: 1.0ug/mlPSMD5 is strongly supported by BioGPS gene expression data to be expressed in Human OVCAR3 cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

PSMD5 antibody

PSMD5 MaxPab polyclonal antibody. Western Blot analysis of PSMD5 expression in human spleen. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

PSMD5 antibody

PSMD5 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

PSMD5 antibody

PSMD5 Rabbit Serum Hu, Ms, Rt E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

PSMD5 antibody

Western Blot analysis of PSMD5 expression in transfected 293T cell line (H00005711-T01) by PSMD5 MaxPab polyclonal antibody.

Lane 1: PSMD5 transfected lysate(56.20 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu, Ms, Rt E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PSMD5 antibody

Immunoperoxidase of monoclonal antibody to PSMD5 on formalin-fixed paraffin-embedded human prostate. [antibody concentration 3 ug/ml] Mouse IgG1 3E2 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PSMD5 antibody

PSMD5 Mouse IgG1 1H7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

PSMD5 antibody

Western Blot: Proteasome 19S Subunit S5b Antibody [NB120-3319] - Figure 1 shows a Western blot of proteasome 19S subunit S5b on purified 26S proteasome using NB120-3319. Rabbit IgG Aff - Purified Hu WB
0.1 mg / €400.00
  Novus Biologicals Inc.

PSMD5 antibody

Immunohistochemistry-Paraffin: Proteasome 26S S5 Antibody [NBP1-87800] - Immunohistochemical staining of human prostate shows strong nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PSMD5

PSMD5 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

PSMD5

PSMD5 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

PSMD5

PSMD5 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

PSMD5

PSMD5 Human Purified
10 µg / €380.00
  Abnova Taiwan Corp.

PSMD5

PSMD5 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

PSMD5

PSMD5 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

PSMD5

PSMD5 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

PSMD5

PSMD5 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

PSMD5 (Human) IP-WB Antibody Pair

PSMD5 (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

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