PTAFR / PAFR antibody

Principal name

PTAFR / PAFR antibody

Alternative names for PTAFR / PAFR antibody

PAF-R, Platelet-activating factor receptor

SwissProt ID

P21556 (Cavpo), P25105 (Human), P46002 (Rat), Q62035 (Mouse), Q9TTY5 (Bovin), Q9XSD4 (Pig)

Gene ID

5724 (PTAFR)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of PTAFR / PAFR antibody

This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation; tumor growth; angiogenesis; metastasis; and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous sigl transduction pathways including phospholipase C; D; A2; mitogen-activated protein kises (MAPKs); and the phosphatidylinositol-calcium second messenger system. Following PAFR activation; cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation; interlization; and down-regulation. Altertive splicing results in multiple transcript variants.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTAFR / PAFR antibody

Predicted cell location: Cytoplasm. Positive control: Human gastric cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human gastric cancer tissue using PTAFR antibody at dilution 1/70, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

PTAFR / PAFR antibody

PTAFR / PAFR Mouse Hu, Ms WB
50 µg / €370.00
  Abnova Taiwan Corp.

PTAFR / PAFR antibody

Immunofluorescence analysis of LOVO cells, using PTAFR Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
50 µg / €205.00
  Assay Biotech

PTAFR / PAFR antibody

Immunofluorescence analysis of LOVO cells, using PTAFR Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
0.1 mg / €310.00
  Assay Biotech

PTAFR / PAFR antibody

Immunohistochemistry-Paraffin: Platelet Activating Factor Receptor Antibody [NBP1-90346] - Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTAFR / PAFR

PTAFR / PAFR Human
2 µg / €450.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PTAFR overexpression lysate

PTAFR overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

PTAFR overexpression lysate

PTAFR overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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