PTCH1 antibody

Principal name

PTCH1 antibody

Alternative names for PTCH1 antibody

PTCH, PTC1, PTC, Patched 1, Protein patched homolog 1

SwissProt ID

O42335 (Cynpy), Q09614 (Caeel), Q13635 (Human), Q61115 (Mouse), Q90693 (Chick), Q98864 (Danre)

Gene ID

5727 (PTCH1), 30181 (ptch2), 19206 (Ptch1)

Available reactivities

Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Can (Canine), Bov (Bovine), Por (Porcine), Xen (Xenopus), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Mouse, Goat, Rat

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of PTCH1 antibody

This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq]. Transcript Variant: This variant (1b) encodes the longest isoform (L). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Nagao K, Togawa N, Fujii K, Uchikawa H, Kohno Y, Yamada M, Miyashita T. Detecting tissue-specific alternative splicing and disease-associated aberrant splicing of the PTCH gene with exon junction microarrays. Hum Mol Genet. 2005 Nov 15;14(22):3379-88. Epub 2005 Oct 3. PMID: 16203740

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTCH1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-PTCH1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500123) Mouse IgG2b OTI5C7 Purified Hu ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

PTCH1 (C-term) antibody

AP22448PU-N PTCH1 antibody staining of Paraffin Embedded Human Colon at 3.8 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €340.00
  Acris Antibodies GmbH

PTCH1 antibody

Immunohistochemistry: Patched 1 Antibody - With exception of malignant gliomas, malignant tissues such as in colo-rectal cancer showed in general a moderate to strong cytoplasmic and membranous positivity.  Image was provided courtesy of the Swedish Human Proteome Resource (HPR) Center. Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PTCH1 antibody

Immunohistochemistry: Patched 1 Antibody [21130002] - With exception of malignant gliomas, malignant tissues such as in colo-rectal cancer showed in general a moderate to strong cytoplasmic and membranous positivity.  Image was provided courtesy of the Swedish Human Proteome Resource (HPR) Center. Rabbit Hu E, P, WB
50 µg / €440.00
  Novus Biologicals Inc.

PTCH1 antibody

Immunohistochemistry-Paraffin: Patched 1 Antibody (5c7) [NBP1-47945] - Immunohistochemical staining of paraffin-embedded Carcinoma of pancreas using anti-PTCH1 mouse monoclonal antibody. Mouse 5c7 Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €620.00
  Novus Biologicals Inc.

PTCH1 (266-280) antibody

Staining of Mouse fetal Kidney lysate using PTCH1 Antibody Cat.-No AP32805PU-N at 2 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

PTCH1 antibody

TA303124 (1µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PTCH1 antibody

Western Blot: Patched 1 Antibody -Analysis of Human PTCH1 in Fetal brain Lysate with anti huPTCH1 at a 1:500 dilution. Rabbit Purified Chk, Hu, Ms, Rt C, E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PTCH1 antibody

Predicted band size: 161kDa. Positive control: Hela cell and mouse lung tissue lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lane1: Hela cel lysate Lane2: Mouse lung tissue lysate Lysates: 40 ug per lane Primary antibody: 1/900 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PTCH1 antibody

Predicted band size: 161kDa. Positive control: Hela cell lysate. Recommended dilution: 1/200-1000. (Gel: 8%SDS-PAGE Lysate: 40 ug Primary antibody: 1/650 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PTCH1 antibody

WB Suggested Anti-PTCH1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

PTCH1 antibody

Western blot analysis on mouse muscle cell lysate using Patched Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PTCH1 antibody

Anti-Patched1 mouse monoclonal antibody (TA500122) immunofluorescent staining of HeLa cells transiently transfected by  pCMV6-ENTRY PTCH1(RC201597) Mouse IgG2b OTI3c2 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PTCH1 antibody

Human recombinant protein fragment corresponding to amino acids 770-1027 of human PTCH1 (NP_000255) produced in E.coli. Mouse IgG1 OTI1H10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PTCH1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTCH1 (RC216999, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PTCH1. Mouse IgG1 OTI1H8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PTCH1 antibody

Human recombinant protein fragment corresponding to amino acids 770-1027 of human PTCH1 (NP_000255) produced in E.coli. Mouse IgG1 OTI5G9 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PTCH1 antibody

Human recombinant protein fragment corresponding to amino acids 770-1027 of human PTCH1 (NP_000255) produced in E.coli. Mouse IgG1 OTI6C10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

PTCH1 antibody

Immunohistochemistry (IHC) analysis of Patched antibody (Cat.-No.: AP06278PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PTCH1 antibody

PTCH1 Goat Aff - Purified Ze E, ICC/IF
0.1 mg / €340.00
  Acris Antibodies GmbH

PTCH1 (1431-1442) antibody

Immunohistochemistry Image: Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Hst, Hu, L, Mky, Ms, Op, Prim, Rb, Rt E, P
50 µg / €470.00
  Acris Antibodies GmbH

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