PTCHD2 antibody

Principal name

PTCHD2 antibody

Alternative names for PTCHD2 antibody

DISP3, KIAA1337, Patched domain-containing protein 2, Protein dispatched homolog 3

SwissProt ID

A3KFU9 (Mouse), Q9P2K9 (Human)

Gene ID

57540 (PTCHD2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Flow Cytometry (F)

Background of PTCHD2 antibody

PTCHD2 Antibody: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in sigling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retil ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism.

General readings

Peart, M.J., et al. Proc. Natl. Acad. Sci. U.S.A. 102(10):3697-3702 (2005).
Katoh, Y., et al. Int. J. Oncol. 26(2):551-556 (2005).
Venter, J.C., et al. Science 291(5507):1304-1351 (2001).

7 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTCHD2 (Center) antibody

Western blot analysis of PTCHD2 in mouse kidney tissue lysate with PTCHD2 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PTCHD2 (C-term) antibody

Immunohistochemistry of PTCHD2 in human testis tissue with PTCHD2 antibody at 5 ug/mL. Rabbit IgG Aff - Purified Hu E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

PTCHD2 (N-term) antibody

Immunohistochemistry of PTCHD2 in human testis tissue with PTCHD2 antibody at 5 ug/mL. Rabbit IgG Aff - Purified Hu E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

PTCHD2 (N-term) antibody

Western blot analysis of PTHD2 Antibody (N-term) Cat.-No AP53502PU-N in NCI-H292 cell line lysates (35ug/lane). This demonstrates the PTHD2 antibody detected the PTHD2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PTCHD2 (Center) Control Peptide

PTCHD2
50 µg / €160.00
  Acris Antibodies GmbH

PTCHD2 (C-term) Control Peptide

PTCHD2
50 µg / €160.00
  Acris Antibodies GmbH

PTCHD2 (N-term) Control Peptide

PTCHD2
50 µg / €160.00
  Acris Antibodies GmbH

7 Item(s)

per page
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