PTGER4 antibody

Principal name

PTGER4 antibody

Alternative names for PTGER4 antibody

PTGER-4, PTGER2, PTGER-2, Prostaglandin E2 receptor EP4 subtype, PGE receptor, EP4 subtype, Prostanoid EP4 receptor

SwissProt ID

P32240 (Mouse), P35408 (Human), P43114 (Rat), Q28691 (Rabit), Q8MJ08 (Bovin)

Gene ID

5734 (PTGER4), 19219 (Ptger4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Mky (Monkey), Bov (Bovine), Chimp (Chimpanzee), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Gorilla

Available hosts

Rabbit, Mouse, Goat

Available applications

Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))

Background of PTGER4 antibody

Prostaglandin E2, a member of the autacoid family of lipid mediators, is a major renal cyclooxygenase product of arachidonic acid metabolism. Prostaglandin E2 binds to four G protein-coupled E-prostanoid receptors, designated EP1, EP2, EP3 and EP4. The expression and function of the prostaglandin E2 receptors have been highly characterized in kidney. EP1, which is predominantly expressed in the collecting duct, couples to Gq proteins to inhibit sodium absorption and increase in intracellular calcium, which act as second messengers. EP2 is coupled to Gs proteins, which stimulate adenylyl cyclase.EP2 has the lowest expression in kidney, but EP2 knockout mice exhibit saltsensitive hypertension, which suggests a role for EP2 in salt excretion. EP3, which is expressed in renal vessels, thick ascending limb and collecting duct, has at least six alternative splice variants that couple to Gi proteins to inhibit cAMP, which subsequently inhibit sodium and water transport. In uterus, EP3 induces the contraction of uterine smooth muscles. EP4 is expressed in glomerulus and collecting duct. It couples to Gs proteins, which stimulate adenylyl cyclase and regulate glomerular tone and renal renin release.

General readings

Echeverria V, Clerman A, Dore S. Stimulation of PGE receptors EP2 and EP4 protects cultured neurons against oxidative stress and cell death following beta-amyloid exposure. Eur J Neurosci. 2005 Nov;22(9):2199-206. PMID: 16262658

  1. Quick-Filters:
  2. Cited (1)
  3. Highly Validated (1)

Items 1 to 20 of 25 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTGER4 (N-Term, Extracell. Dom.) antibody

Anti-PTGER4 / EP4 antibody IHC of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Mky, Prim ICC/IF, P
50 µg / €345.00
  OriGene Technologies, Inc.

PTGER4 (C-term) antibody

Anti-PTGER4 / EP4 antibody IHC of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, GP, Hst, Hu, Mky, Ms, Op, Prim, Rb, Rt, Ze P
50 µg / €345.00
  OriGene Technologies, Inc.

PTGER4 antibody

TA302476 (0.1µg/ml) staining of Human Testes lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PTGER4 antibody

Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane: LoVo cells, Primary antibody: PTGER4 Antibody at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PTGER4 antibody

PTGER4 Antibody (Center) (Cat. #TA325166) western blot analysis in HL-60,K562 cell line and mouse brain lysates (35ug/lane).This demonstrates the PTGER4 antibody detected the PTGER4 protein (arrow). Rabbit IgG Purified Bov, Hu, Ms, Rb, Rt WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

PTGER4 antibody

Western blot (WB) analysis of EP4 antibody (Cat.-No.: AP01202PU-N) in extracts from COLO205 cells. Rabbit Aff - Purified Hu ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PTGER4 (C-term) antibody

Cells expressing vector only - immunostained with target antibody Rabbit Aff - Purified Bear, Can, Eq, Hu, Mky, Ms, Prim, Rt ICC/IF, P
50 µg / €470.00
  Acris Antibodies GmbH

PTGER4 antibody

PTGER4 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

PTGER4 antibody

Western Blot analysis of PTGER4 expression in transfected 293T cell line (H00005734-T04) by PTGER4 MaxPab polyclonal antibody.

Lane 1: PTGER4 transfected lysate(53.10 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

PTGER4 antibody

PTGER4 polyclonal antibody ( Cat # PAB6969 ) ( 0.1 µg/ml ) staining of human testis lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

PTGER4 antibody

Immunofluorescence analysis of MCF7 cells, using PE2R4 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

PTGER4 antibody

Immunofluorescence analysis of MCF7 cells, using PE2R4 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

PTGER4 antibody

Western blot analysis of EP4 expression in Ramos (A); HeLa (B) whole cell lysates. Rabbit Aff - Purified Hu, Mky WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

PTGER4 antibody

Western blot analysis of EP4 expression in Ramos (A); HeLa (B) whole cell lysates. Rabbit Aff - Purified Hu, Mky WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

PTGER4 antibody

Western blot analysis of EP4 expression in Ramos (A); HeLa (B) whole cell lysates. Rabbit Aff - Purified Hu, Mky WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

PTGER4 antibody

Western Blot: EP4 prostaglandin receptor Antibody [NB100-2801] - NB100-2801 (0.1ug/ml) staining of Human Testes lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

PTGER4 antibody

Western Blot: EP4 Antibody [NBP1-00811] - Western blot (WB) analysis of EP4 (H362) antibody in extracts from COLO205 cells. Rabbit Aff - Purified Hu ICC/IF, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

PTGER4 antibody

Immunohistochemistry-Paraffin: Prostaglandin E Receptor EP4 Antibody [NBP1-84833] - Immunohistochemical staining of human small intestine shows strong cytoplasmic and membranous positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

PTGER4 antibody

Immunohistochemistry-Paraffin: Prostaglandin E Receptor EP4 Antibody [NBP1-84834] - Immunohistochemical staining of human kidney shows strong cytoplasmic and membranous positivity in cells in tubules. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTGER4

PTGER4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Items 1 to 20 of 25 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn