PTGER4 antibody

Principal name

PTGER4 antibody

Alternative names for PTGER4 antibody

PTGER-4, PTGER2, PTGER-2, Prostaglandin E2 receptor EP4 subtype, PGE receptor, EP4 subtype, Prostanoid EP4 receptor

SwissProt ID

P32240 (Mouse), P35408 (Human), P43114 (Rat), Q28691 (Rabit), Q8MJ08 (Bovin)

Gene ID

5734 (PTGER4), 19219 (Ptger4)

Available reactivities

Can (Canine), Eq (Equine), Hu (Human), Mky (Monkey), Ms (Mouse), Prim (Primate), Rt (Rat), Bear, Bt (Bat), Bov (Bovine), GP (Guinea Pig), Hst (Hamster), Op (Opossum), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse, Goat

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))

Background of PTGER4 antibody

Prostaglandin E2, a member of the autacoid family of lipid mediators, is a major renal cyclooxygenase product of arachidonic acid metabolism. Prostaglandin E2 binds to four G protein-coupled E-prostanoid receptors, designated EP1, EP2, EP3 and EP4. The expression and function of the prostaglandin E2 receptors have been highly characterized in kidney. EP1, which is predominantly expressed in the collecting duct, couples to Gq proteins to inhibit sodium absorption and increase in intracellular calcium, which act as second messengers. EP2 is coupled to Gs proteins, which stimulate adenylyl cyclase.EP2 has the lowest expression in kidney, but EP2 knockout mice exhibit saltsensitive hypertension, which suggests a role for EP2 in salt excretion. EP3, which is expressed in renal vessels, thick ascending limb and collecting duct, has at least six alternative splice variants that couple to Gi proteins to inhibit cAMP, which subsequently inhibit sodium and water transport. In uterus, EP3 induces the contraction of uterine smooth muscles. EP4 is expressed in glomerulus and collecting duct. It couples to Gs proteins, which stimulate adenylyl cyclase and regulate glomerular tone and renal renin release.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTGER4 (N-Term, Extracell. Dom.) antibody

  PTGER4 / EP4 Rabbit Polyclonal (N-Terminus) Antibody  
Anti-PTGER4 / EP4 antibody IHC of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Mky, Prim ICC/IF, P
50 µg / €400.00
  OriGene Technologies, Inc.

PTGER4 (C-term) antibody

  PTGER4 / EP4 Rabbit Polyclonal (C-Terminus) Antibody  
Anti-PTGER4 / EP4 antibody IHC of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, GP, Hst, Hu, Mky, Ms, Op, Prim, Rb, Rt, Ze P
50 µg / €400.00
  OriGene Technologies, Inc.

PTGER4 antibody

  Goat Polyclonal Antibody against EP4 prostaglandin receptor  
TA302476 (0.1µg/ml) staining of Human Testes lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

PTGER4 antibody

  Anti-PTGER4 Rabbit Polyclonal Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane: LoVo cells, Primary antibody: PTGER4 Antibody at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PTGER4 antibody

  Rabbit polyclonal PTGER4 Antibody (Center)  
PTGER4 Antibody (Center) (Cat. #TA325166) western blot analysis in HL-60,K562 cell line and mouse brain lysates (35ug/lane).This demonstrates the PTGER4 antibody detected the PTGER4 protein (arrow). Rabbit IgG Purified Bov, Hu, Ms, Rb, Rt WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

PTGER4 antibody

Western blot (WB) analysis of EP4 antibody (Cat.-No.: AP01202PU-N) in extracts from COLO205 cells. Rabbit Aff - Purified Hu ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

PTGER4 (C-term) antibody

Cells expressing vector only - immunostained with target antibody Rabbit Aff - Purified Bear, Can, Eq, Hu, Mky, Ms, Prim, Rt ICC/IF, P
50 µg / €470.00
  Acris Antibodies GmbH

PTGER4 antibody

Immunofluorescence analysis of MCF7 cells, using PE2R4 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

PTGER4 antibody

Immunofluorescence analysis of MCF7 cells, using PE2R4 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

PTGER4 - human gene knockout kit via CRISPR

PTGER4 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

PTGER4 - human gene knockout kit via CRISPR

PTGER4 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PTGER4 - human gene knockout kit via CRISPR

PTGER4 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PTGER4 - human gene knockout kit via CRISPR

PTGER4 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ptger4 - mouse gene knockout kit via CRISPR

Ptger4 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Ptger4 - mouse gene knockout kit via CRISPR

Ptger4 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ptger4 - mouse gene knockout kit via CRISPR

Ptger4 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ptger4 - mouse gene knockout kit via CRISPR

Ptger4 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTGER4

  Recombinant protein of human prostaglandin E receptor 4 (subtype EP4) (PTGER4)  
PTGER4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PTGER4 (mGFP-tagged) - Human prostaglandin E receptor 4 (subtype EP4) (PTGER4), 200 uL, >10^7 TU/mL

Lenti ORF particles, PTGER4 (mGFP-tagged) - Human prostaglandin E receptor 4 (subtype EP4) (PTGER4), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, PTGER4 (Myc-DDK tagged) - Human prostaglandin E receptor 4 (subtype EP4) (PTGER4) , 200 uL, >10^7 TU/mL

Lenti ORF particles, PTGER4 (Myc-DDK tagged) - Human prostaglandin E receptor 4 (subtype EP4) (PTGER4) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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