PTGIS antibody

Principal name

PTGIS antibody

Alternative names for PTGIS antibody

Prostacyclin Synthase, CYP8, CYP8A1, Prostaglandin I2 Synthase

SwissProt ID

O35074 (Mouse), Q16647 (Human), Q29626 (Bovin), Q62969 (Rat)

Gene ID

5740 (PTGIS), 282021, 19223 (Ptgis), 25527

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), GP (Guinea Pig), Rb (Rabbit), Rt (Rat), Sh (Sheep), Por (Porcine), Ze (Zebrafish), Can (Canine), Eq (Equine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Frozen Sections (C), Immunoprecipitation (IP)

Background of PTGIS antibody

PTGIS is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygeses which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functiol similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygeses which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functiol similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

17 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTGIS antibody

  Rabbit polyclonal anti-PTGIS antibody  
Western blot analysis of extracts from K562 cells, using PTGIS antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

PTGIS antibody

  Rabbit Polyclonal Anti-PTGIS Antibody  
WB Suggested Anti-PTGIS Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

PTGIS (N-term) antibody

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CYP8A1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

PTGIS (C-term) antibody

Formalin-fixed and paraffin-embedded human prostate carcinoma reacted withPTGIS Antibody (C-term) Cat.-No AP17980PU-N, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

PTGIS - human gene knockout kit via CRISPR

PTGIS - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ptgis - mouse gene knockout kit via CRISPR

Ptgis - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Ptgis - mouse gene knockout kit via CRISPR

Ptgis - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ptgis - mouse gene knockout kit via CRISPR

Ptgis - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ptgis - mouse gene knockout kit via CRISPR

Ptgis - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTGIS

  Recombinant protein of human prostaglandin I2 (prostacyclin) synthase (PTGIS)  
PTGIS Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PTGIS overexpression lysate

PTGIS overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PTGIS (mGFP-tagged) - Human prostaglandin I2 (prostacyclin) synthase (PTGIS), 200 uL, >10^7 TU/mL

Lenti ORF particles, PTGIS (mGFP-tagged) - Human prostaglandin I2 (prostacyclin) synthase (PTGIS), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, PTGIS (Myc-DDK tagged) - Human prostaglandin I2 (prostacyclin) synthase (PTGIS) , 200 uL, >10^7 TU/mL

Lenti ORF particles, PTGIS (Myc-DDK tagged) - Human prostaglandin I2 (prostacyclin) synthase (PTGIS) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ptgis (GFP-tagged) - Mouse prostaglandin I2 (prostacyclin) synthase (Ptgis), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ptgis (GFP-tagged) - Mouse prostaglandin I2 (prostacyclin) synthase (Ptgis), 200 uL, >10^7 TU/mL  
200 µl / €1,120.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ptgis (Myc-DDK-tagged) - Mouse prostaglandin I2 (prostacyclin) synthase (Ptgis), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ptgis (Myc-DDK-tagged) - Mouse prostaglandin I2 (prostacyclin) synthase (Ptgis), 200 uL, >10^7 TU/mL  
200 µl / €1,000.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ptgis (GFP-tagged ORF) - Rat prostaglandin I2 (prostacyclin) synthase (Ptgis), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ptgis (GFP-tagged ORF) - Rat prostaglandin I2 (prostacyclin) synthase (Ptgis), 200 uL, >10^7 TU/mL  
200 µl / €1,120.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ptgis (Myc-DDK-tagged ORF) - Rat prostaglandin I2 (prostacyclin) synthase (Ptgis), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ptgis (Myc-DDK-tagged ORF) - Rat prostaglandin I2 (prostacyclin) synthase (Ptgis), 200 uL, >10^7 TU/mL  
200 µl / €1,002.00
  OriGene Technologies, Inc.

17 Item(s)

per page
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